Pyrrolomorphinans as δ opioid receptor antagonists. The role of steric hindrance in conferring selectivity

Journal of Medicinal Chemistry

Volumn 40, Issue 13, 1997, Pages 1977-1981

  Farouz Grant, F ^a   Portoghese, P S ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DELTA OPIATE RECEPTOR ANTAGONIST; MORPHINAN DERIVATIVE; NALTRINDOLE; OPIATE RECEPTOR; PYRROLOMORPHINAN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG POTENCY; DRUG SYNTHESIS; RECEPTOR AFFINITY; RECEPTOR BINDING; SMOOTH MUSCLE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ELECTRIC STIMULATION; ENKEPHALIN, LEUCINE-2-ALANINE; ETHYLKETOCYCLAZOCINE; GUINEA PIGS; MALE; MICE; MODELS, CHEMICAL; MORPHINANS; MORPHINE; MUSCLE, SMOOTH; PYRROLES; RECEPTORS, OPIOID, DELTA; STEREOISOMERISM;

EID: 0030917995     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970189y     Document Type: Article

References (14)

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