Nucleophilic addition of nitrones to ketones: Development of a new catalytic asymmetric nitrone-aldol reaction

Chemistry - A European Journal

Volumn 8, Issue 24, 2002, Pages 5652-5661

  Bøgevig, Anders ^a   Gothelf, Kurt V ^a   Jørgensen, Karl Anker ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Aldol reaction; Amines; Asymmetric catalysis; Enantioselectivity; Nitrones

Indexed keywords

ADDITION REACTIONS; AMINES; CARBONYLATION; CATALYSIS;

NUCLEOPHILIC ADDITION;

KETONES;

1 PHENYL 1,2 PROPANEDIONE; 1,9 DECADIEN 5,6 DIONE; 2,3 BUTANEDIONE; ACRYLIC ACID METHYL ESTER; ALPHA KETOESTER; AMINE; CARBON; CARBONYL DERIVATIVE; DIETHYL KETOMALONATE; DIKETONE; ESTER DERIVATIVE; KETONE; LEUCINE; N BENZYL C METHYLNITRONE; N BENZYLNITRONE; N TERT BUTYL C METHYLNITRONE; NITRONE; NITRONE DERIVATIVE; PROLINE; PYRROLIDINE DERIVATIVE; TRIFLUOROACETOPHENONE; UNCLASSIFIED DRUG;

ADDITION REACTION; ALDOL REACTION; ARTICLE; CATALYSIS; CELL NUCLEUS; CHEMICAL BOND; CHEMICAL REACTION; CHIRALITY; ELECTRON; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0037122183     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3765(20021216)8:24<5652::AID-CHEM5652>3.0.CO;2-J     Document Type: Article

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25. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
26. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
27. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
28. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
29. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
30. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
31. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
32. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
33. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
34. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
35. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
36. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
37. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
38. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
39. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
40. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
41. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
42. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
43. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
44. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew.
45. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
46. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
47. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
48. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
49. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
50. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
51. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
52. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
53. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
54. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
55. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
56. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
57. For selected recent developments in organo-catalyzed reactions see: aldol reactions: a) B. List, W. Notz, J. Am. Chem. Soc. 2000, 122, 7386; b) A. Cordova, W. Notz, C. F. Barbas III, J. Org. Chem. 2002, 67, 301; c) K. Sakthivel, W. Notz, T. Bui, C. F. Barbas III, J. Am. Chem. Soc. 2001, 123, 5260; d) B. List, P. Pojarliev, C. Castello, Org. Lett. 2001, 3, 573; e) B. List, R. A. Lerner, C. F. Barbas III, J. Am. Chem. Soc. 2000, 122, 2395; f) A. Bøgevig, N. Kumaragurubaran, K. A. Jørgensen, Chem. Commun. 2002, 620; g) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 6798; Mannich reactions: h) W. Notz, K. Sakthivel, T. Bui, G. Zhong, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 199; i) B. List, P. Pojarliev, W. T. Biller, H. J. Martin, J. Am. Chem. Soc. 2002, 124, 827; j) B. List, J. Am. Chem. Soc. 2000, 122, 9336; k) A. Cordova, S. Watanabe, F. Tanaka, W. Notz, C. F. Barbas III, C. F. J. Am. Chem. Soc. 2002, 124, 1866; l) A. Cordova, W. Notz, G. Zhong, J. M. Betancort, C. F. Barbas III, J. Am. Chem. Soc. 2002, 124, 1842; Robinson annulation reactions: m) T. Bui, C. F. Barbas III, Tetrahedron Lett. 2000, 41, 6951; aminations reactions: n) A. Bøgevig, K. Juhl, N. Kumaragubaran, W. Zhuang, K. A. Jørgensen, Angew. Chem. 2002, 114, 1868; Angew. Chem. Int. Ed. 2002, 45, 1790; o) B. List, J. Am. Chem. Soc. 2002, 124, 5656; p) N. Kumaragubaran, K. Juhl, W. Zhuang, A. Bøgevig, K. A. Jørgensen, J. Am. Chem. Soc. 2002, 124, 6254; Michael addition reactions: q) J. M. Betancort, C. F. Barbas III, Org. Lett. 2001, 3, 3737; r) J. M. Betancort, K. Sakthivel, R. Thayumanavan, C. F. Barbas III, Tetrahedron Lett. 2001, 42, 4441; Diels-Alder reactions: s) K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 4243; t) A. B. Northrup, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 2458; 1,3-dipolar cycloaddition reactions: u) W. S. Jen, J. J. M. Wiener, D. W. C. MacMillan, J. Am. Chem. Soc. 2000, 122, 9874; v) S. Karlsson, H.-E. Högsberg, Tetrahedron: Asymmetry 2002, 13, 923; Friedel-Crafts rections: w) N. A. Paras, D. W. C. MacMillan, J. Am. Chem. Soc. 2001, 123, 4370; x) J. F. Austin, D. W. C. MacMillan, J. Am. Chem. Soc. 2002, 124, 1172; conjugate additions: y) V. Pham, S. Hanessian, Org. Lett. 2000, 2, 2975; z) T. E. Horstmann, D. J. Guerin, S. J. Miller, Angew. Chem. 2000, 112, 3781; Angew. Chem. Int. Ed. 2000, 39, 3635; Baylis-Hillmann reactions: aa) Y. Iwabuchi, M. Nakatani, N. Yokoyama, S. Hatakeyama, J. Am. Chem. Soc. 1999, 121, 10219; ab) B. List, Tetrahedron 2002, 58, 5573; ac) H. Gröger, J. Wilken, Angew. Chem. 2001, 113, 545; Angew. Chem. Int. Ed. 2001, 44, 529; ad) P. I. Dalko, L. Moisan, Angew. Chem. 2001, 113, 3840; Angew. Chem. Int. Ed. 2001, 44, 3726.
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