Potential for the 2G single nucleotide polymorphism in the promoter of matrix metalloproteinase to enhance gene expression in normal stromal cells

Cancer Research

Volumn 62, Issue 24, 2002, Pages 7200-7202

  Wyatt, Colby A ^a   Coon, Charles I ^a   Gibson, Jennifer J ^b   Brinckerhoff, Constance E ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DNA; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; GUANINE NUCLEOTIDE; INTERLEUKIN 1; INTERSTITIAL COLLAGENASE; LACTALBUMIN; MESSENGER RNA;

ARTICLE; CANCER GROWTH; CANCER INVASION; CONTROLLED STUDY; DNA POLYMORPHISM; EXTRACELLULAR MATRIX; FIBROBLAST; GENE EXPRESSION REGULATION; GENOTYPE; HUMAN; HUMAN CELL; PREPUCE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; STROMA CELL;

ALLELES; CELLS, CULTURED; DIPLOIDY; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENOTYPE; HUMANS; MATRIX METALLOPROTEINASE 1; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STROMAL CELLS;

EID: 0037115612     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Brinckerhoff, C. E., and Matrisian, L. M. Matrix metalloproteinases: A tail of a frog that became a prince. Nat. Rev. Mol. Cell. Biol., 3: 207-214, 2002.
2. Brinckerhoff, C. E., Rutter, J. L., and Benbow, U. Interstitial collagenases as markers of tumor progression. Clin. Cancer Res., 6: 4823-4830, 2000.
3. Rutter, J. L., Mitchell, T. I., Buttice, G., Meyers, J., Gusella, J. F., Ozelius, L. J., and Brinckerhoff, C. E. A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter creates an Ets binding site and augments transcription. Cancer Res., 58: 5321-5325, 1998.
4. Vincenti, M. P., White, L. A., Schroen, D. J., Benbow, U., and Brinckerhoff, C. E. Regulating expression of the gene for matrix metalloproteinase-1 (collagenase): Mechanisms that control enzyme activity, transcription, and mRNA stability. Crit. Rev. Eukaryot. Gene Expr., 6: 391-411, 1996.
5. Zhu, Y., Spitz, M. R., Lei, L., Mills, G. B., and Wu, X. A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances lung cancer susceptibility. Cancer Res., 61: 7825-7829, 2001.
6. Kanamori, Y., Matsushima, M., Minaguchi, T., Kobayashi, K., Sagae, S., Kudo, R., Terakawa, N., and Nakamura, Y. Correlation between expression of the matrix metalloproteinase-1 gene in ovarian cancers and an insertion/deletion polymorphism in its promoter region; Cancer Res., 59: 4225-4227, 1999.
7. Nishioka, Y., Kobayashi, K., Sagae, S., Ishioka, S., Nishikawa, A., Matsushima, M., Kanamori, Y., Minaguchi, T., Nakamura, Y., Tokino, T., and Kudo, R. A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter in endometrial carcinomas. Jpn. J. Cancer Res., 91: 612-615, 2000.
8. Ye, S., Dhillon, S., Turner, S. J., Bateman, A. C., Theaker, J. M., Pickering, R. M., Day, I., and Howell, W. M. Invasiveness of cutaneous malignant melanoma is influenced by matrix metalloproteinase 1 gene polymorphism. Cancer Res., 61: 1296-1298, 2001.
9. Ghilardi, G., Biondi, M. L., Mangoni, J., Leviti, S., DeMonti, M., Guagnellini, E., and Scorza, R. Matrix metalloproteinase-1 promoter polymorphism 1G/2G is correlated with colorectal cancer invasiveness. Clin Cancer Res., 7: 2344-2346, 2001.
10. Wiseman, B. S., and Werb, Z. Stromal effects on mammary gland development and breast cancer. Science (Wash. DC), 296: 1046-1049, 2002.
11. Singer, C. F., Kronsteiner, N., Marton, E., Kubista, M., Cullen, K. J., Hirtenlehner, K., Seifert, M., and Kubista, E. MMP-2 and MMP-9 expression in breast cancer-derived human fibroblasts is differentially regulated by stromal-epithelial interactions. Breast Cancer Res. Treat., 72: 69-77, 2002.
12. Liotta, L. A., and Kohn, E. C. The microenvironment of the tumour-host interface. Nature (Lond.), 411: 375-379, 2001.
13. Vincenti, M. P., Coon, C. I., and Brinckerhoff, C. E. Nuclear factor κB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1,β-stimulated synovial fibroblasts. Arthritis Rheum., 41: 1987-1994, 1998.
14. Fujimoto, T., Parry, S., Urbanek, M., Sammel, M., Macones, G., Kuivaniemi, H., Romero, R., and Strauss, J. F., III. A single nucleotide polymorphism in the matrix metalloproteinase-1 (MMP-1) promoter influences amnion cell MMP-1 expression and risk for preterm premature rupture of the fetal membranes. J Biol Chem., 277: 6296-6302, 2002.
15. Yan, H., Yuan, W., Velculescu, V. E., Vogelstein, B., and Kinzler, K. W. Allelic variation in human gene expression. Science (Wash. DC), 297: 1143, 2002.
16. Wandel, E., Grasshoff, A., Mittag, M., Haustein, U. F., and Saalbach, A. Fibroblasts surrounding melanoma express elevated levels of matrix metalloproteinase-1 (MMP-1) and intercellular adhesion molecule-1 (ICAM-1) in vitro. Exp. Dermatol., 9: 34-41, 2000.