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Volumn 186, Issue 12, 2002, Pages 1761-1769

Participation of Ras and extracellular regulated kinase in the hyperplastic response of middle-ear mucosa during bacterial otitis media

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; PROTEIN FARNESYLTRANSFERASE INHIBITOR; RAS PROTEIN;

EID: 0037114939     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/345798     Document Type: Article
Times cited : (12)

References (60)
  • 2
    • 0028269563 scopus 로고
    • Acidic and basic FGF mRNA expression in the middle ear mucosa during experimental acute and chronic otitis media
    • Koutnouyan HA, Baird A, Ryan AF. Acidic and basic FGF mRNA expression in the middle ear mucosa during experimental acute and chronic otitis media. Laryngoscope 1994;104:350-8.
    • (1994) Laryngoscope , vol.104 , pp. 350-358
    • Koutnouyan, H.A.1    Baird, A.2    Ryan, A.F.3
  • 3
    • 0027524158 scopus 로고
    • Growth factors during proliferation of the middle ear mucosa
    • Ryan AF. A Baird. Growth factors during proliferation of the middle ear mucosa. Acta Otolaryngol 1993;113:68-74.
    • (1993) Acta Otolaryngol , vol.113 , pp. 68-74
    • Ryan, A.F.1    Baird, A.2
  • 4
    • 0015178350 scopus 로고
    • Ultrastructural pathology of the middle ear mucosa in serous otitis media
    • Lim D, Birck H. Ultrastructural pathology of the middle ear mucosa in serous otitis media. Ann Otol Rhinol Laryngol 1971;80:838-53.
    • (1971) Ann Otol Rhinol Laryngol , vol.80 , pp. 838-853
    • Lim, D.1    Birck, H.2
  • 6
    • 0018426543 scopus 로고
    • Willart ECT The effect of experimental tubal obstruction on the middle ear
    • Kuijpers W. van der Beck JMH. Willart ECT The effect of experimental tubal obstruction on the middle ear. Acta Otolaryngol 1979;87:345-52.
    • (1979) Acta Otolaryngol , vol.87 , pp. 345-352
    • Kuijpers, W.1    Van der Beck, J.M.H.2
  • 7
    • 0018962008 scopus 로고
    • Experimental otitis media following middle ear inoculation of nonviable streptococcus pneumoniae
    • Lowell S, Juhn SK, Giebink GS. Experimental otitis media following middle ear inoculation of nonviable streptococcus pneumoniae. Ann Otol Rhinol Laryngol 1980;89:479-82.
    • (1980) Ann Otol Rhinol Laryngol , vol.89 , pp. 479-482
    • Lowell, S.1    Juhn, S.K.2    Giebink, G.S.3
  • 8
    • 0031005923 scopus 로고    scopus 로고
    • The tympanic membrane and middle ear mucosa during non-typeable Haemophilus influenzae and Haemophilus influenzae type b acute otitis media: A study in the rat
    • Magnuson K, Hermansson A, Melhus A, Hellstrom S. The tympanic membrane and middle ear mucosa during non-typeable Haemophilus influenzae and Haemophilus influenzae type b acute otitis media: A study in the rat. Acta Otolaryngol 1997;117:396-405.
    • (1997) Acta Otolaryngol , vol.117 , pp. 396-405
    • Magnuson, K.1    Hermansson, A.2    Melhus, A.3    Hellstrom, S.4
  • 10
    • 0029906793 scopus 로고    scopus 로고
    • Growth factors during endotoxin-induced experimental otitis media
    • DeMaria TF, Billy JM, Danahey DG. Growth factors during endotoxin-induced experimental otitis media. Acta Otolaryngol 1996;116:854-6.
    • (1996) Acta Otolaryngol , vol.116 , pp. 854-856
    • DeMaria, T.F.1    Billy, J.M.2    Danahey, D.G.3
  • 11
    • 0022624881 scopus 로고
    • Secondary immune response in the middle ear: Physiological, anatomical and immunological observations
    • Ryan AF, Catanzaro A, Wasserman S. Harris JP. Secondary immune response in the middle ear: Physiological, anatomical and immunological observations. Ann Otol Rhinol Laryngol 1986;95:242-9.
    • (1986) Ann Otol Rhinol Laryngol , vol.95 , pp. 242-249
    • Ryan, A.F.1    Catanzaro, A.2    Wasserman, S.3    Harris, J.P.4
  • 12
    • 0025966918 scopus 로고
    • The response to human rIL-1, rIL-2 and rTNF in the middle ear of guinea pigs
    • Catanzaro A, Ryan AF, Butcher S. The response to human rIL-1, rIL-2 and rTNF in the middle ear of guinea pigs. Laryngoscope 1991;101:271.
    • (1991) Laryngoscope , vol.101 , pp. 271
    • Catanzaro, A.1    Ryan, A.F.2    Butcher, S.3
  • 13
    • 84971721053 scopus 로고
    • Tympanic effusions in children: Long-term results of treatment by myringotomy, aspiration, and indwelling tubes
    • Mawson S, Fagan P. Tympanic effusions in children: Long-term results of treatment by myringotomy, aspiration, and indwelling tubes. J Laryngol Otol 1972;86:105-19.
    • (1972) J Laryngol Otol , vol.86 , pp. 105-119
    • Mawson, S.1    Fagan, P.2
  • 14
    • 0017550126 scopus 로고
    • Tympanosclerosis
    • Morgan W Jr. Tympanosclerosis. Laryngoscope 1977;87:1821-5.
    • (1977) Laryngoscope , vol.87 , pp. 1821-1825
    • Morgan W., Jr.1
  • 15
    • 0015399541 scopus 로고
    • Grommets and glue ears: Two-year results
    • Kilby D, Richards S, Hart G. Grommets and glue ears: Two-year results. J Laryngol Otol 1972;86:881-8.
    • (1972) J Laryngol Otol , vol.86 , pp. 881-888
    • Kilby, D.1    Richards, S.2    Hart, G.3
  • 16
    • 0007363245 scopus 로고
    • Pathogenesis of attic cholesteatoma: The metaplasia theory
    • McCabe BF, Sade J, Abramson M, eds. Birmingham, AL: Aesculapius
    • Sade J. Pathogenesis of attic cholesteatoma: the metaplasia theory. In: McCabe BF, Sade J, Abramson M, eds. Cholesteatoma: First International Conference. Birmingham, AL: Aesculapius, 1978;212-32.
    • (1978) Cholesteatoma: First International Conference , pp. 212-232
    • Sade, J.1
  • 17
    • 0001125811 scopus 로고
    • Chronic adhesive otitis
    • Cawthorne T. Chronic adhesive otitis. J Laryngol Otol 1956;70:559-64.
    • (1956) J Laryngol Otol , vol.70 , pp. 559-564
    • Cawthorne, T.1
  • 18
    • 0017660347 scopus 로고
    • Cholesteatoma surgery: Residual and recurrent disease - A review of 1,024 cases
    • Sheehy J, Brackmann D, Graham M. Cholesteatoma surgery: residual and recurrent disease - a review of 1,024 cases. Ann Otol Rhinol Laryngol 1977;86:451-62.
    • (1977) Ann Otol Rhinol Laryngol , vol.86 , pp. 451-462
    • Sheehy, J.1    Brackmann, D.2    Graham, M.3
  • 20
    • 0024594301 scopus 로고
    • Fibroblast growth factors
    • Baird A, Walicke PA. Fibroblast growth factors. Br Med Bull 1989;45:438-52.
    • (1989) Br Med Bull , vol.45 , pp. 438-452
    • Baird, A.1    Walicke, P.A.2
  • 21
    • 0025039910 scopus 로고
    • Fibroblast growth factor - Chemical structure and biological function
    • Gospodarowicz D. Fibroblast growth factor - Chemical structure and biological function. Clin Orthop 1990;257:231-48.
    • (1990) Clin Orthop , vol.257 , pp. 231-248
    • Gospodarowicz, D.1
  • 23
    • 0028104202 scopus 로고
    • Regulation of signal transduction and signal diversity by receptor oligomerization
    • Lemmon MA, Schlessinger J. Regulation of signal transduction and signal diversity by receptor oligomerization. Trends Biochem Sci 1994;19:459-63.
    • (1994) Trends Biochem Sci , vol.19 , pp. 459-463
    • Lemmon, M.A.1    Schlessinger, J.2
  • 24
    • 0033996413 scopus 로고    scopus 로고
    • Ras protein signaling
    • Olson M, Marais R. Ras protein signaling. Semin Immunol 2000;12:63-73.
    • (2000) Semin Immunol , vol.12 , pp. 63-73
    • Olson, M.1    Marais, R.2
  • 25
    • 0032522849 scopus 로고    scopus 로고
    • Inhibiting ras prenylation increases the radiosensitivity of human tumor cell lines with activating mutations of ras oncogenes
    • Berhard E, McKenna W, Hamilton A, et al. Inhibiting ras prenylation increases the radiosensitivity of human tumor cell lines with activating mutations of ras oncogenes. Cancer Res 1998;58:1754-61.
    • (1998) Cancer Res , vol.58 , pp. 1754-1761
    • Berhard, E.1    McKenna, W.2    Hamilton, A.3
  • 26
    • 0030865773 scopus 로고    scopus 로고
    • Ras farnesyltransferase: A new therapeutic target
    • Leonard D. Ras farnesyltransferase: A new therapeutic target. J Med Chem 1997;40:19.
    • (1997) J Med Chem , vol.40 , pp. 19
    • Leonard, D.1
  • 27
    • 0027422247 scopus 로고
    • The pathways to signal achievement
    • Egan S, Weinberg R. The pathways to signal achievement. Nature 1993;365, 781-6.
    • (1993) Nature , vol.365 , pp. 781-786
    • Egan, S.1    Weinberg, R.2
  • 28
    • 0032493812 scopus 로고    scopus 로고
    • Increasing complexity of the Ras signaling pathway
    • Vojtek A, Der CJ. Increasing complexity of the Ras signaling pathway. J Biol Chem 1998;273:19925-8.
    • (1998) J Biol Chem , vol.273 , pp. 19925-19928
    • Vojtek, A.1    Der, C.J.2
  • 29
    • 0026908231 scopus 로고
    • Prenoids and palmitate: Lipids that control the biological activity of Ras proteins
    • Kato K, Der CJ, Buss J. Prenoids and palmitate: Lipids that control the biological activity of Ras proteins. Semin Cancer Biol 1992;3:179-88.
    • (1992) Semin Cancer Biol , vol.3 , pp. 179-188
    • Kato, K.1    Der, C.J.2    Buss, J.3
  • 30
    • 0029966304 scopus 로고    scopus 로고
    • Protein prenyltransferases
    • Casey P. Protein prenyltransferases. J Biol Chem 1996;271:5289-92.
    • (1996) J Biol Chem , vol.271 , pp. 5289-5292
    • Casey, P.1
  • 31
    • 0028973293 scopus 로고
    • Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes
    • Lerner E, Qian Y, Blaskovich M, et al. Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes. J Biol Chem 1995;270:26802-6.
    • (1995) J Biol Chem , vol.270 , pp. 26802-26806
    • Lerner, E.1    Qian, Y.2    Blaskovich, M.3
  • 32
    • 0029817122 scopus 로고    scopus 로고
    • Mediation of signal tranasduction in keratinocytes of human middle ear cholesteatoma by ras protein
    • Huang C, Chen C, Huang T, Shinoda H. Mediation of signal tranasduction in keratinocytes of human middle ear cholesteatoma by ras protein. Eur Arch Otorhinolaryngol 1996;253:385-9.
    • (1996) Eur Arch Otorhinolaryngol , vol.253 , pp. 385-389
    • Huang, C.1    Chen, C.2    Huang, T.3    Shinoda, H.4
  • 33
  • 34
    • 0028789009 scopus 로고
    • Experimental recurrent otitis media induced by Haemophilus influenzae: Protection and serum antibodies
    • Melhus A, Hermansson A, Akkoyunlu M, Forsgren A, Prellner K. Experimental recurrent otitis media induced by Haemophilus influenzae: Protection and serum antibodies. Am J Otolaryngol 1995;16:383-90.
    • (1995) Am J Otolaryngol , vol.16 , pp. 383-390
    • Melhus, A.1    Hermansson, A.2    Akkoyunlu, M.3    Forsgren, A.4    Prellner, K.5
  • 35
    • 0028340471 scopus 로고
    • Nontypeable and encapsulated Haemophilus influenzae yield different clinical courses of experimental otitis media
    • Melhus A, Hermansson A, Prellner K. Nontypeable and encapsulated Haemophilus influenzae yield different clinical courses of experimental otitis media. Acta Otolaryngol 1994;114:289-94.
    • (1994) Acta Otolaryngol , vol.114 , pp. 289-294
    • Melhus, A.1    Hermansson, A.2    Prellner, K.3
  • 36
    • 84961004698 scopus 로고
    • The comparative pathology of otitis media - Experimental and human. II. The histopathology of experimental otitis of the guinea pig with particular reference to experimental cholesteatoma
    • Friedmann I. The comparative pathology of otitis media - Experimental and human. II. The histopathology of experimental otitis of the guinea pig with particular reference to experimental cholesteatoma. J Laryngol 1955;69: 588-601.
    • (1955) J Laryngol , vol.69 , pp. 588-601
    • Friedmann, I.1
  • 38
    • 0033628672 scopus 로고    scopus 로고
    • Relationship between ras pathways and cell cycle control
    • Ewen M. Relationship between ras pathways and cell cycle control. Prog Cell Cycle Res 2000;4:1-17.
    • (2000) Prog Cell Cycle Res , vol.4 , pp. 1-17
    • Ewen, M.1
  • 39
    • 0032541625 scopus 로고    scopus 로고
    • Non-Ras targets of farnesyltransferase inhibitors: Focus on Rho
    • Du W, Lebowitz P, Prendergast G. Non-Ras targets of farnesyltransferase inhibitors: Focus on Rho. Oncogene 1998;17:1439-45.
    • (1998) Oncogene , vol.17 , pp. 1439-1445
    • Du, W.1    Lebowitz, P.2    Prendergast, G.3
  • 40
    • 0028331522 scopus 로고
    • Expression of myc, fos and Ha-ras associated with chemically induced cell proliferation in the rat liver
    • Goldsworthy T, Goldsworthy S, Sprankle C, Butterworth B. Expression of myc, fos and Ha-ras associated with chemically induced cell proliferation in the rat liver. Cell Prolif 1994;27:269-78.
    • (1994) Cell Prolif , vol.27 , pp. 269-278
    • Goldsworthy, T.1    Goldsworthy, S.2    Sprankle, C.3    Butterworth, B.4
  • 41
    • 0032859475 scopus 로고    scopus 로고
    • Inhibition of human tumor cell growth in vitro and in vivo by a specific inhibitor of human farnesyltransferase: BIM-46068
    • Prevost G, Pradines A, Viossat I, et al. Inhibition of human tumor cell growth in vitro and in vivo by a specific inhibitor of human farnesyltransferase: BIM-46068. Int J Cancer 1999;83:283-7.
    • (1999) Int J Cancer , vol.83 , pp. 283-287
    • Prevost, G.1    Pradines, A.2    Viossat, I.3
  • 43
    • 0030952552 scopus 로고    scopus 로고
    • Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines
    • Lerner E, Zhang T, Knowles D, Qian Y, Hamilton A, Sevti S. Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines. Oncogene 1997;15:1283-8.
    • (1997) Oncogene , vol.15 , pp. 1283-1288
    • Lerner, E.1    Zhang, T.2    Knowles, D.3    Qian, Y.4    Hamilton, A.5    Sevti, S.6
  • 44
    • 0031575908 scopus 로고    scopus 로고
    • ERK and p38 MAP kinase pathways are mediators of intestinal epithelial wound-induced signal transduction
    • Dieckgraefe B, Weems D, Santoro S, Alpers D. ERK and p38 MAP kinase pathways are mediators of intestinal epithelial wound-induced signal transduction. Biochem Biophys Res Commun 1997;233:389-94.
    • (1997) Biochem Biophys Res Commun , vol.233 , pp. 389-394
    • Dieckgraefe, B.1    Weems, D.2    Santoro, S.3    Alpers, D.4
  • 45
    • 0032578702 scopus 로고    scopus 로고
    • Suppression of Erk activation and in vivo growth in esophageal cancer cells by the dominant negative Ras mutant, N116Y
    • Senmaru N, Shichinohe T, Takeuchi M, et al. Suppression of Erk activation and in vivo growth in esophageal cancer cells by the dominant negative Ras mutant, N116Y. Int J Cancer 1998;78:366-71.
    • (1998) Int J Cancer , vol.78 , pp. 366-371
    • Senmaru, N.1    Shichinohe, T.2    Takeuchi, M.3
  • 46
    • 0026733002 scopus 로고
    • PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity
    • Qui M, Green S. PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity. Neuron 1992;9:705-17.
    • (1992) Neuron , vol.9 , pp. 705-717
    • Qui, M.1    Green, S.2
  • 47
    • 0033545565 scopus 로고    scopus 로고
    • Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells
    • Plattner R, Gupta S, Khosravi-Far R, et al. Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells. Oncogene 1999;18:1807-17.
    • (1999) Oncogene , vol.18 , pp. 1807-1817
    • Plattner, R.1    Gupta, S.2    Khosravi-Far, R.3
  • 48
    • 0033173291 scopus 로고    scopus 로고
    • Lack of elevated MAP kinase (Erk) activity in pancreatic carcinomas despite oncogenic K-ras expression
    • Yip-Schneider M, Lin A, Barnard D, Sweeney C, Marshall M. Lack of elevated MAP kinase (Erk) activity in pancreatic carcinomas despite oncogenic K-ras expression. Int J Oncol 1999;15:271-9.
    • (1999) Int J Oncol , vol.15 , pp. 271-279
    • Yip-Schneider, M.1    Lin, A.2    Barnard, D.3    Sweeney, C.4    Marshall, M.5
  • 50
    • 0030296550 scopus 로고    scopus 로고
    • Evidence for a Ras/Ral signaling cascade
    • Feig L, Urano T, Cantor S. Evidence for a Ras/Ral signaling cascade. Trends Biochem Sci 1996;21:438-41.
    • (1996) Trends Biochem Sci , vol.21 , pp. 438-441
    • Feig, L.1    Urano, T.2    Cantor, S.3
  • 52
    • 13344281006 scopus 로고    scopus 로고
    • Identification of AF-6 and canoe as putative targets for Ras
    • Kuriyama M, Harada N, Kuroda S, et al. Identification of AF-6 and canoe as putative targets for Ras. J Biol Chem 1996;27:607-10.
    • (1996) J Biol Chem , vol.27 , pp. 607-610
    • Kuriyama, M.1    Harada, N.2    Kuroda, S.3
  • 53
    • 0028859266 scopus 로고
    • A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1
    • Han L, Colicelli J. A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1. Mol Cell Biol 1995;15:1318-23.
    • (1995) Mol Cell Biol , vol.15 , pp. 1318-1323
    • Han, L.1    Colicelli, J.2
  • 54
    • 0033553558 scopus 로고    scopus 로고
    • Platelet-derived growth factor activates p38 mitogen-activated protein kinase through a Ras-dependent pathway that is important for actin reorganization and cell migration
    • Matsumoto T, Yokote K, Tamura K, et al. Platelet-derived growth factor activates p38 mitogen-activated protein kinase through a Ras-dependent pathway that is important for actin reorganization and cell migration. J Biol Chem 1999;274:13954-60.
    • (1999) J Biol Chem , vol.274 , pp. 13954-13960
    • Matsumoto, T.1    Yokote, K.2    Tamura, K.3
  • 55
    • 0028074316 scopus 로고
    • Phosphatidylinositol-3-OH kinase as a direct target of Ras
    • Rodriguez-Viciana P, Warne P, Dhand R, et al. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 1994;370:527-32.
    • (1994) Nature , vol.370 , pp. 527-532
    • Rodriguez-Viciana, P.1    Warne, P.2    Dhand, R.3
  • 56
    • 0034194348 scopus 로고    scopus 로고
    • Pancreatic cancer cell proliferation is phosphatidylinositol 3-kinase dependent
    • Perugini R, McDade T, Vittimberga F, Callery M. Pancreatic cancer cell proliferation is phosphatidylinositol 3-kinase dependent. J Surg Res 2000;90:39-40.
    • (2000) J Surg Res , vol.90 , pp. 39-40
    • Perugini, R.1    McDade, T.2    Vittimberga, F.3    Callery, M.4
  • 57
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic Ras provokes premature cell senescence associated with accumulation of p53 and p161NK4a
    • Serrano M, Lin A, McCurrach M, Beach D, Lowe S. Oncogenic Ras provokes premature cell senescence associated with accumulation of p53 and p161NK4a. Cell 1997;88:593-602.
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.2    McCurrach, M.3    Beach, D.4    Lowe, S.5
  • 58
    • 0030871667 scopus 로고    scopus 로고
    • Land. High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1
    • Sewing B, Wiseman A, Lloyd H, Land. High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1. Mol Cell Biol 1997;17:5588-97.
    • (1997) Mol Cell Biol , vol.17 , pp. 5588-5597
    • Sewing, B.1    Wiseman, A.2    Lloyd, H.3
  • 59
    • 0032537819 scopus 로고    scopus 로고
    • Signals from Ras and Rho GTPases interact to regulate expression of p21 Waf1/Cip1
    • Olson M, Paterson H. Marshall C. Signals from Ras and Rho GTPases interact to regulate expression of p21 Waf1/Cip1. Nature 1998;394:295-9.
    • (1998) Nature , vol.394 , pp. 295-299
    • Olson, M.1    Paterson, H.2    Marshall, C.3
  • 60
    • 0031028730 scopus 로고    scopus 로고
    • Suppression of c-Myc-induced apoptosis by ras signaling through PI(3)K and PKB
    • Kauffmann-Zeh A, Rodrigues-Viciana P, Ulrich E, et al. Suppression of c-Myc-induced apoptosis by ras signaling through PI(3)K and PKB. Nature 1997;385:544.
    • (1997) Nature , vol.385 , pp. 544
    • Kauffmann-Zeh, A.1    Rodrigues-Viciana, P.2    Ulrich, E.3


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