CD45 tyrosine phosphatase inhibits erythroid differentiation of umbilical cord blood CD34+ cells associated with selective inactivation of Lyn

Blood

Volumn 100, Issue 13, 2002, Pages 4440-4445

  Harashima, Akira ^a   Suzuki, Motoyuki ^a   Okochi, Ayumi ^a   Yamamoto, Mayuko ^a   Matsuo, Yoshinobu ^a   Motoda, Ryuichi ^a   Yoshioka, Tamotsu ^a   Orita, Kunzo ^a  

^a HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CD45 ANTIGEN; ERYTHROPOIETIN; INTERLEUKIN 3; JANUS KINASE; PHOSPHATASE; PROTEIN KINASE LYN; PROTEIN TYROSINE KINASE; TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL ASSAY; CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELL STIMULATION; CELL STRUCTURE; CONTROLLED STUDY; ENZYME INACTIVATION; ERYTHROBLAST; ERYTHROID CELL; ERYTHROPOIESIS; HEMATOPOIESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STROMA; STRUCTURE ANALYSIS; UMBILICAL CORD BLOOD;

EID: 0037114749     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-03-0864     Document Type: Article

References (33)

1. Thomas ML. The leukocyte common antigen family. Annu Rev Immunol. 1989;7:339-369.
2. Trowbridge IS. CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu Rev Immunol. 1994;12:85-116.
3. Thomas ML, Brown EJ. Positive and negative regulation of Src-family membrane kinases by CD45. Immunol Today. 1999;20:406-411.
4. Koretzky GA, Picus J, Thomas ML, Weiss A. Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway. Nature. 1990;346:66-68.
5. Justement LB, Campbell KS, Chien NC, Cambier JC. Regulation of B cell receptor signal transduction and phosphorylation by CD45. Science. 1991;252:1839-1842.
6. Cahir McFarland ED, Hurley TR, Pingel JT, Sefton BM, Shaw A, Thomas ML. Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor. Proc Natl Acad Sci U S A. 1993;90:1402-1406.
7. - B cells. J Immunol. 1997;158:2663-2669.
8. Katagiri T, Ogimoto M, Hasegawa K, et al. CD45 negatively regulates Lyn activity by dephosphorylating both positive and negative regulatory tyrosine residues in immature B cells. J Immunol. 1999;163:1321-1326.
9. Katagiri T, Ogimoto M, Hasegawa K, Mizuno K, Yakura H. Selective regulation of Lyn tyrosine kinase by CD45 in immature B cells. J Biol Chem. 1995;270:27987-27990.
10. D'Oro U, Ashwell JD. The CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes. J Immunol. 1999;162:1879-1883.
11. Berger SA, Mak TW, Paige CJ. Leukocyte common antigen (CD45) is required for immunoglobulin E-mediated degranulation of mast cells. J Exp Med. 1994;180:471-476.
12. Roach T, Slater S, Koval M, et al. CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion. Curr Biol. 1997;7:408-417.
13. Irie-Sasaki J, Sasaki T, Matsumoto W, et al. CD45 is a JAK phosphatase and negatively regulates cytokine receptor signaling. Nature. 2001;409:349-354.
14. Penninger JM, Irie-Sasaki J, Sasaki T, Oliveirados-Santos AJ. CD45: New jobs for an old acquaintance. Nat Immunol. 2001;2:389-396.
15. Ihle JN. Cytokine receptor signaling. Nature. 1995;377:591-594.
16. Corey SJ, Anderson SM. Src-related protein tyrosine kinases in hematopoiesis. Blood. 1999;93:1-14.
17. Wojchowski DM, Gregory RC, Miller CP, Pandit AK, Pircher TJ. Signal transduction in the erythropoietin receptor system. Exp Cell Res. 1999;253:143-156.
18. Tilbrook PA, Ingley E, Williams JH, Hibbs ML, Klinken SP. Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells. EMBO J. 1997;16:1610-1619.
19. Tilbrook PA, Palmer GA, Bittorf T, et al. Maturation of erythroid cells and erythroleukemia development are affected by the kinase activity of Lyn. Cancer Res. 2001;61:2453-2458.
20. Chin H, Arai A, Wakao H, Kamiyama R, Miyasaka N, Miura O. Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway. Blood. 1998;91:3734-3745.
21. Itoh K, Tezuka H, Sakoda H, et al. Reproducible establishment of hematopoietic supportive stromal cell lines from murine bone marrow. Exp Hematol. 1989;17:145-153.
22. Schwinzer R. Cluster report: CD45/CD45R. In: Knapp W, Dorken B, Gilks WR, et al. eds. Leukocyte Typing IV. New York, NY: Oxford University Press; 1989:628-634.
23. Callus BA, Busfield SJ, Klinken SP. Diaminofluorene is more sensitive than benzidine for detecting hemoglobin in erythropoietin responsive J2E cells. Hemoglobin. 1995;19:7-19.
24. Okumura N, Tsuji K, Nakahata T. Changes in cell surface antigen expressions during proliferation and differentiation of human erythroid progenitors. Blood. 1992;80:642-650.
25. Nakahata T, Okumura N. Cell surface antigen expression in human erythroid progenitors: Erythroid and megakaryocytic markers. Leuk Lymphoma. 1994;13:401-409.
26. Adachi T, Pazdrak K, Stafford S, Alam R. The mapping of the Lyn kinase binding site of the common beta subunit of IL-3/granulocyte-macrophage colony-stimulating factor/IL-5 receptor. J Immunol. 1999;162:1496-1501.
27. Anderson SM, Jorgensen B. Activation of src-related tyrosine kinases by IL-3. J Immunol. 1995;155:1660-1670.
28. Hibbs ML, Tarlinton DM, Armes J, et al. Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease. Cell. 1995;83:301-311.
29. Craig W, Poppema S, Little MT, Dragowska W, Lansdorp PM. CD45 isoform expression on human haemopoietic cells at different stages of development. Br J Haematol. 1994;88:24-30.
30. Blank N, Kriegel M, Hieronymus T, et al. CD45 tyrosine phosphatase controls common gamma-chain cytokine-mediated STAT and extracellular signal-related kinase phosphorylation in activated human lymphoblasts: Inhibition of proliferation without induction of apoptosis. J Immunol. 2001;166:6034-6040.
31. Broxmeyer HE, Lu L, Hangoc G, et al. CD45 cell surface antigens are linked to stimulation of early human myeloid progenitor cells by interleukin 3 (IL-3), granulocyte/macrophage colony-stimulating factor (GM-CSF), a GM-CSF/IL-3 fusion protein, and mast cell growth factor (a c-kit ligand). J Exp Med. 1991;174:447-458.
32. Sgroi D, Varki A, Braesch-Andersen S, Stamenkovic I. CD22, a B cell-specific immunoglobulin superfamily member, is a sialic acid-binding lectin. J Biol Chem. 1993;268:7011-7018.
33. Symons A, Cooper DN, Barclay AN. Characterization of the interaction between galectin-1 and lymphocyte glycoproteins CD45 and Thy-1. Glycobiology. 2000;10:559-563.