Anticonvulsant preclinical profile of CHF 3381 - Dopaminergic and glutamatergic mechanisms

Pharmacology Biochemistry and Behavior

Volumn 70, Issue 1, 2001, Pages 157-166

  Gandolfi, Ottavio ^a   Bonfante, Veronica ^a   Voltattorni, Manuela ^a   Dall'Olio, Rossella ^a   Poli, Alessandro ^a   Pietra, Claudio ^b   Villetti, Gino ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b CHIESI FARMACEUTICI S P A   (Italy)

Author keywords

Anticonvulsants; Behavior; Dopamine (DA); Neurotoxicity; Primary cell cultures; Radioligand binding assays; Rat

Indexed keywords

3 (2 CARBOXY 2 PHENYLETHENYL) 4,6 DICHLORO 1H INDOLE 2 CARBOXYLIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; ANTICONVULSIVE AGENT; CHF 3381; DIZOCILPINE; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; GLUTAMIC ACID; GLYCINE; GLYCINE RECEPTOR; LIGAND; N (2 INDANYL)GLYCINAMIDE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POLYAMINE; SODIUM CHLORIDE; SPERMIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; BINDING SITE; BRAIN CELL; BRAIN SLICE; BRAIN SYNAPTOSOME; CELL CULTURE; CONTROLLED STUDY; DOPAMINE UPTAKE; DOPAMINERGIC ACTIVITY; DRUG EFFECT; ELECTRIC SHOCK; KINETICS; LIGAND BINDING; MALE; MOLECULAR INTERACTION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC MEMBRANE;

ANIMALS; ANTICONVULSANTS; BEHAVIOR, ANIMAL; CELLS, CULTURED; CEREBRAL CORTEX; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ELECTRIC STIMULATION; GLUTAMIC ACID; GLYCINE; INDANS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 0034862212     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(01)00591-3     Document Type: Article

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