Novel estradiol derivatives labeled with Ru, W, and Co complexes. Influence on hormone-receptor affinity of several organometallic groups at the 17α position

Chemistry - A European Journal

Volumn 8, Issue 22, 2002, Pages 5241-5249

  Top, Siden ^a   El Hafa, Hassane ^a   Vessières, Anne ^a   Huché, Michel ^a   Vaissermann, Jacqueline ^b   Jaouen, Gérard ^a  

^a PSL RESEARCH UNIVERSITY   (France)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

Bioorganometallic chemistry; Cobalt; Molecular modeling; Ruthenium; Steroids; Tungsten

Indexed keywords

ADDITION REACTIONS; COBALT; HORMONES; RUTHENIUM; TUNGSTEN;

MOLECULAR-MODELING; RELATIVE-BINDING AFFINITY (RBA);

ORGANOMETALLICS;

COBALT; COBALT COMPLEX; DRUG DERIVATIVE; ESTRADIOL; ESTRADIOL DERIVATIVE; ESTRADIOL RECEPTOR; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; RUTHENIUM; RUTHENIUM COMPLEX; TUNGSTEN; TUNGSTEN DERIVATIVE;

ANIMAL; ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPLEX FORMATION; CRYSTAL STRUCTURE; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; RECEPTOR AFFINITY; SHEEP; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; COBALT; CRYSTALLOGRAPHY, X-RAY; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN CONFORMATION; RECEPTORS, ESTROGEN; RUTHENIUM; SHEEP; TUNGSTEN;

EID: 0037112620     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3765(20021115)8:22<5241::AID-CHEM5241>3.0.CO;2-M     Document Type: Article

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