High-frequency Doppler ultrasound monitors the effects of antivascular therapy on tumor blood flow

Cancer Research

Volumn 62, Issue 22, 2002, Pages 6371-6375

  Goertz, David E ^a   Yu, Joanne L ^a   Kerbel, Robert S ^a   Burns, Peter N ^a   Foster, F Stuart ^a  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HOE 33342; N ACETYLCOLCHINOL PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLOOD FLOW VELOCITY; BLOOD VESSEL FUNCTION; DIAGNOSTIC IMAGING; DOPPLER ECHOGRAPHY; DRUG EFFECT; ENDOTHELIUM CELL; GENE TARGETING; MELANOMA CELL; MONITORING; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; TUMOR BLOOD FLOW; TUMOR GROWTH; VOLUMETRY;

ANGIOGENESIS INHIBITORS; ANIMALS; BENZIMIDAZOLES; HUMANS; MELANOMA; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; ORGANOPHOSPHORUS COMPOUNDS; STAINING AND LABELING; TUMOR CELLS, CULTURED; ULTRASONICS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0037112419     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Jain, R, K., Schlenger, K., Hockel, M., and Yuan, F. Quantitative angiogenesis assays: Progress and problems. Nat. Med., 3: 1203-1208, 1997.
2. Anderson, H., Price, P., Blomley, M., Leach, M. O., and Workman, P. Measuring changes in human turnout vasculature in response to therapy using functional imaging techniques. Br. J. Cancer. 85: 1085-1093, 2001.
3. Gee, M. S., Saunders, H. M., Lee, J. C., Sanzo, J. F., Jenkins, W. T., Evans, S. M., Trinchieri, G., Sehgal, C. M., Feldman, M. D., and Lee, W. M. F. Doppler ultrasound changes in tumor perfusion during antivascular, therapy associated with vascular anatomic alterations. Cancer Res., 61: 2974-2982, 2001.
4. Donnelly, E. F., Geng, L., Wojcicki, W. E., and Fleischer, A. C., Hallahan, D. E. Quantified power Doppler US of tumor blood flow correlates with microscopic quantification of tumor blood vessels. Radiology, 219: 166-170, 2001.
5. Kruse. D. Fornaris R., Silverman R., Coleman, D., and Ferrara, K. A swept-scanning mode for estimation of velocities in the microvasculature. IEEE Trans. Ultrason. Ferroelect. Freq. Contr., 45: 1437-1440, 1998.
6. Goertz, D. E., Christopher, D. A., Yu, J. L., Kerbel, R. S., Burns, P. N., and Foster, F. S. High frequency color flow imaging of the microcirculation. Ultrasound Med. Biol., 26: 63-71, 2000.
7. Foster, F. S., Burns, P. N., Simpson, D. H., Wilson, S. R., Christopher, D. A., and Goertz, D. E. Ultrasound for the visualization and quantification of tumor microcirculation. Cancer Metastasis Rev., 19: 131-138, 2000.
8. Chaplin, D. J., and Dougherty, G. J. Tumour vasculature as a target for cancer therapy. Br. J. Cancer, 80: S57-S64, 1999.
9. Smith, K. A., Hill S. A., Begg, A. C., and Denekamp, J. Validation of the fluorescent dye Hoechst 33342 as a vascular space marker in tumors. Br. J. Cancer, 57: 247-253, 1988.
10. Ishikawa, M., Dennis. J. W., Man, S., and Kerbel, R. S. Isolation and characterization of spontaneous wheat-germ agglutinin-resistant human-melanoma mutants displaying remarkably different metastatic profiles in nude-mice. Cancer Res., 48: 665-670, 1988.
11. Ishikawa, M., Fernandez, B., and Kerbel, R. S. Highly pigmented human melanoma variant which metastasizes widely in nude mice including to skin and brain. Cancer Res., 48: 4897-4903, 1988.
12. Cornil, I., Man, S., Fernandez, B., and Kerbel, R. S. Enhanced tumorigenicity, melanogenesis, and metastasis of a human malignant melanoma observed after subdermal implantation in nude mice. J. Natl. Cancer Inst. (Bethesda), 81: 938-944, 1989.
13. D. H. Evans and W. N. McDicken (eds.), Doppler Ultrasound: Physics, Instrumentation and Signal Processing, pp. 229-284. New York: Wiley, 2000.
14. Foster, F. S., Pavlin, C. J., Harasiewicz, K. A., Christopher, D. A., and Turnbull, D. H. Advances in ultrasound biomicroscopy. Ultrasound Med. Biol., 26: 1-27, 2000.
15. Goertz, D. E. High Frequency Ultrasound Imaging of the Microcirculation (Thesis). Toronto, Canada: University of Toronto, 2002.
16. Rubin, J. M., Bude, R. O., Carson, P. L., Bree, R. L., and Adler, R. S. Power Doppler US: A potentially useful alternative to mean frequency based color Doppler. Radiology, 190: 853-856, 1994.
17. Dark, G. D., Hill, S. A., Prise, V. E., Tozer, G. M., Pettit, G. R., and Chaplin, D. J. Combretastatin A-4: An agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res., 57: 1829-1834, 1997.
18. Tozer, G. M., Prise, V. E., Wilson, J., Cemazar, M., Shan, S., Dewhirst, M. W., Barber, P. R., Vojnovic, B., and Chaplin, D. J. Mechanisms associated with tumor vascular shut-down induced by A-4 phosphate: Intravital microscopy and measurement of vascular permeability. Cancer Res., 61: 6413-6422, 2001.
19. Maxwell, R. K., Wilson, J., Prise, V. E., Vojnovic, B., Rustin, G. J., and Lodge, G. M. Evaluation of the anti-vascular effects of combretastatin in rodent tumours by dynamic contrast enhanced MRI. NMR Biomed., 15: 89-98, 2002.
20. Klement, G., Baruchel, S., Rak, J., Man, S., Clark, C., Hickline, D., Bohlen, P., and Kerbel, R. S. Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without ovary toxicity. J. Clin. Investig., 105: R15-R24.
21. Browder, T., Butterfield, C. E., Kraling, B. M., Shi, B., Marshall, B., O'Reilly, M. S., and Folkman, J. Antiangiogenic scheduling of chemotherapy improved efficacy against experimental drug-resistant cancer. Cancer Res., 60: 1878-1886, 2000.