A genetic investigation of the essential role of glutathione. Mutations in the proline biosynthesis pathway are the only suppressors of glutathione auxotrophy in yeast

Journal of Biological Chemistry

Volumn 276, Issue 10, 2001, Pages 7011-7016

  Spector, Daniel ^a,c   Labarre, Jean ^a   Toledano, Michel B ^a,b,c  

^a DIF   (France)

^b RUTGERS UNIVERSITY   (United States)

^c UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; DNA; ENZYMES; GENETIC ENGINEERING; MUTAGENESIS;

CHRONIC STRESS CONDITIONS;

BIOCHEMISTRY;

DNA; GLUTATHIONE; PROLINE; DRUG DERIVATIVE; GAMMA GLUTAMYLPHOSPHATE; GAMMA-GLUTAMYL PHOSPHATE; GLUTAMINE; HYDROGEN PEROXIDE; MESYLIC ACID ETHYL ESTER; MUTAGENIC AGENT;

ARTICLE; AUXOTROPHY; BIOSYNTHESIS; CONTROLLED STUDY; DNA SYNTHESIS; GENE MUTATION; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SUPPRESSOR GENE; ALLELE; DOSE RESPONSE; GENE DELETION; GENE LIBRARY; GENE REPRESSION; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; THIN LAYER CHROMATOGRAPHY;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

ALLELES; CHROMATOGRAPHY, THIN LAYER; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHYL METHANESULFONATE; GENE DELETION; GENE LIBRARY; GLUTAMINE; GLUTATHIONE; HYDROGEN PEROXIDE; MUTAGENS; MUTATION; OXIDATIVE STRESS; PHENOTYPE; PROLINE; SACCHAROMYCES CEREVISIAE; SUPPRESSION, GENETIC;

EID: 0035831449     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009814200     Document Type: Article

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