Organization of the multifunctional enzyme type 1: Interaction between N- and C-terminal domains is required for the hydratase-1/isomerase activity

Biochemical Journal

Volumn 367, Issue 2, 2002, Pages 433-441

  Kiema, Tiila Riikka ^a   Taskinen, Jukka P ^a   Pirilä, Päivi L ^a   Koivuranta, Kari T ^a   Wierenga, Rik K ^a   Hiltunen, J Kalervo ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

oxidation; Lipid metabolism; Peroxisome; Protein engineering; Structure function

Indexed keywords

DATABASE SYSTEMS; DEHYDROGENATION; DIMERIZATION; ENZYMES; GENES; OXIDATION; PROTEINS;

GENE DUPLICATION;

BIOCHEMISTRY;

DINUCLEOTIDE; HYDROLYASE; HYDROXYACYL COENZYME A DEHYDROGENASE; ISOMERASE; MITOCHONDRIAL ENZYME; OXIDOREDUCTASE; PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; DATA BASE; DIMERIZATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STABILITY; FATTY ACID OXIDATION; GENE DELETION; GENE DUPLICATION; GENETIC ENGINEERING; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HYDROGENATION; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; RAT;

3-HYDROXYACYL COA DEHYDROGENASES; AMINO ACID SEQUENCE; ANIMALS; ENOYL-COA HYDRATASE; ESCHERICHIA COLI; ISOMERASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 0037108898     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020292     Document Type: Article

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