Morphological alterations induced by loud noise in the myocardium: The role of benzodiazepine receptors

Microscopy Research and Technique

Volumn 59, Issue 2, 2002, Pages 136-146

  Gesi, Marco ^a   Fornai, Francesco ^a   Lenzi, Paola ^a   Ferrucci, Michela ^a   Soldani, Paola ^a   Ruffoli, Riccardo ^a   Paparelli, Antonio ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Electron microscopy; Heart; Mitochondria; Rat; Stress

Indexed keywords

CARDIOVASCULAR SYSTEM; MITOCHONDRIA; NOISE POLLUTION;

BENZODIAZEPINES; EFFECT OF NOISE; ENVIRONMENTAL STRESS; EXPERIMENTAL ANIMALS; MITOCHONDRIAS; MORPHOLOGICAL ALTERATION; NOISE EXPOSURE; STRESS FACTORS; SUB-CELLULAR; SUBCHRONIC EXPOSURE;

LIGANDS;

4' CHLORODIAZEPAM; BENZODIAZEPINE DERIVATIVE; BENZODIAZEPINE RECEPTOR; CLONAZEPAM; DIAZEPAM; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE;

ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR SYSTEM; CONTROLLED STUDY; DRUG RECEPTOR BINDING; EXPOSURE; HEART ATRIUM; HEART MITOCHONDRION; HEART MUSCLE; HEART PROTECTION; HEART VENTRICLE; MORPHOLOGY; NOISE; NONHUMAN; PRIORITY JOURNAL; RAT; STRESS;

ANIMALIA;

EID: 0037108622     PISSN: 1059910X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jemt.10186     Document Type: Article

References (87)

1. Alario P, Gamallo A, Beato MJ, Trancho G. 1987. Body weight gain, food intake and adrenal development in chronic noise stressed rats. Physiol Behav 40:29-32.
2. Althaus-Salzmann M, Carafoli E, Jakob A. 1980. Ca2+, K+ redistribution and alpha-adrenergic activation of glycogenolytic rat livers. Eur J Biochem 106:241-248.
3. Altura BM, Altura BT, Gebrewold A, Ising H, Gunther T. 1992. Noise-induced hypertension and magnesium in rats: relationship to microcirculation and calcium. J Appl Physiol 72:194-202.
4. Andren L, Hansson RL, Eggersten R. 1983. Circulatory effects of noise. Acta Med Scand 213:31-35.
5. Ashraf M, Halverson C. 1978. Ultrastructural modifications of nexuses (gap junctions) during early myocardial ischemia. J Mol Cellular Cardiol 10:263-269.
6. Bach V, Libert JP, Tassi P, Wittersheim G, Johnson LC, Ehrhart J. 1991. Cardiovascular responses and electroencephalogram disturbances to intermittent noise: effects of nocturnal heat and daytime exposure. Eur J Appl Physiol 63:330-337.
7. Banister EW, Tomanek RJ, Cvorkov N. 1971 Ultrastructural modifications in rat heart: responses to exercise and training. Am J Physiol 220:1935-1940.
8. Beardwood CJ, Mundell CA, Utian WH. 1975. Gonadotropin excretion in response to audiostimulation of human subjects. Am J Obstet Gynaecol 121:682-687.
9. Bengtsson B, Marchall JM. 1983. Estrogen inhibition of noradrenaline release in the rabbit oviduct. Acta Physiol Scand 117:321-329.
10. Bischoff MB, Dean WD, Bucci TJ, Frics LA. 1969. Ultrastructural changes in myocardium of animals after five months residence at 14,110 feet. Federation Proc 28:1268-1273.
11. Bowers WD Jr, Burlington RF, Whitten BK, Daum RC, Posiviata MA. 1971. Ultrastructural and metabolic alterations in myocardium from altitude-acclimated rats. Am J Physiol 220:1885-1889.
12. Breschi MC, Scatizzi R, Martinotti E, Pellegrini A, Soldani P, Paparelli A. 1994. Morphofunctional changes in the noradrenergic innervation of the rat cardiovascular system after varying duration of noise stress. Int J Neurosci 75:73-81.
13. Burlington RF, Whitten BK, Sidel CM, Posiviata MA, Salkovits IA. 1970. Effect of hypoxia on glycolysis in perfused heart from rats and ground squirrels (Citellus lateralis). Comp Biochem Physiol 35:403-414.
14. Castillo-Ferrando JR, Perez-Ojeda E, Encina JL, Serrano JS. 1985. Modifications of the inotropic effect of digoxin by diazepam in rat left atria. J Pharm Pharmacol 37:828-832.
15. Caulfield J, Klionsky B. 1959. Myocardial ischemia and early infarction: an electron microscopic study. Am J Pathol 35:389-523.
16. Cohen S, Krantz DS, Evans GW, Stockols D. 1981. Cardiovascular and behavioural effects of community noise. Am Sci 69:528-535.
17. Colletti V, Fiorino FG. 1987. Myocardial activity during noise exposure. Acta Otolaryngol (Stockh) 104:217-224.
18. Collins MG, Vanhoutte PM. 1977. Vascular reactivity of isolated kidneys from male and female spontaneously hypertensive rats. Circ Res 41:759-767.
19. Corrodi H, Fuxe K, Lidbrink P, Olson L. 1971. Minor tranquilizers, stress and central catecholamine neurons. Brain Res 29:1-16.
20. 2+ exchange. TiPS 14:408-413.
21. De Boer SF, Slangen JL, Van der Gugten J. 1988. Adaptation of plasma catecholamine and corticosterone responses to short-term repeated noise stress in rats. Physiol Behav 44:273-280.
22. De Boer SF, Van der Gugten J, Slangen JL. 1989. Plasma catecholamine and corticosterone responses to predictable and unpredictable noise stress in rats. Physiol Behav 45:789-795.
23. De Souza EB, Anholt RR, Murphy KM, Snyder SH, Kuhar MJ. 1985. Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis. Endocrinology 116:567-573.
24. Drugan RC. 1996. Peripheral benzodiazepine receptors: molecular pharmacology to possible physiological significance in stress-induced hypertension. Clin Neuropharmacol 19:475-496.
25. Drug Evaluation Annual 1995. Am Med Assoc USA p 219-259.
26. Elgoyhen B, Adler-Graschinsky E. 1989. Diminution by benzodiazepines of the chronotropic responses to noradrenaline in rat isolated atria. Eur J Pharmacol 164:467-478.
27. Erdö SL, Wolff L. 1990. γ-Aminobutyric acid outside the mammalian brain. J Neurochem 54:363-372.
28. Fares F, Weizman A, Zlotogorski D, Gavish M. 1987. Ontogenetic development of peripheral benzodiazepine binding sites in rat brain, heart and lung. Brain Res 408:381-384.
29. Ferrarese C, Mennini T, Pecora N, Pierpaoli C, Frigo M, Marzorati C, Gobbi M, Bizzi A, Codegoni A, Garattini S, Frattola L. 1991. Diazepam binding inhibitor (DBI) increases after acute stress in rat. Neuropharmacology 30:1445-1452.
30. Forbes MS, Sperelakis N. 1985. Intercalated discs of mammalian heart: a review of structure and function. Tissue Cell 17:605-648.
31. Gamallo A, Alario P, Villanua MA, Nava MP. 1988. Effect of chronic stress in the blood pressure in the rat: ACTH administration. Horm Metab Res 20:336-338.
32. Gesi M, Riva A, Soldani P, Fornai F, Natale G, Lenzi P, Pellegrini A, Paparelli A. 1999a. Central and peripheral benzodiazepine ligands prevent mitochondrial damage induced by noise exposure in the rat myocardium: an ultrastructural study. Anat Rec 255:334-341.
33. Gesi M, Soldani P, Lenzi P, Fornai F, Pellegrini A, Natale G, Paparelli A. 1999b. Morphological and biochemical events in the rat myocardium after noise stress exposure. It J Anat Embryol 104:187.
34. Gesi M, Fornai F, Lenzi P, Soldani P, Ferrucci M, Paparelli A. 2000. Ultrastructural localization of calcium deposits in rat myocardium after loud noise exposure. J Submicrosc Cytol Pathol 32:585-590.
35. Gloag D. 1980. Noise: hearing loss and psychological effects. Br Med J 281:1325-1327.
36. Goldstein DS, Dionne R, Sweet J, Gracely R, Brewer HB, Gregg R, Keiser HR. 1982. Circulatory, plasma catecholamine, cortisol, lipid, and psycological responses to a real-life stress (third molar extractions): effects of diazepam sedation and of inclusion of epinephrine with the local anesthetic. Psychosom Med 44:259-272.
37. Grundemar L, Hakanson R. 1994. Neuropeptide Y effector systems: perspectives for drug development. Trends Pharmacol Sci 15:153-159.
38. Gunter TE, Pfeiffer DR. 1990. Mechanisms by which mitochondria transport calcium. Am J Physiol 258:C755-C786.
39. Gunter TE, Gunter KK, Sheu S, Gavin CE. 1994. Mitochondrial calcium transport: physiological and pathological relevance. Am J Physiol 267:C313-C339.
40. Halestrap AP, Kerr PM, Javadov S, Woodfield KY. 1998. Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart. Biochim Biophys Acta 1366:79-94.
41. Hirsch T, Decaudin D, Susin SA, Marchetti P, Larochette N, Resche-Rigon M, Kroemer G. 1998. PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection. Exp Cell Res 241:426-434.
42. Jennings RB, Herdson PB, Sommers HM. 1969. Structural and functional abnormalities in mitochondria isolated from ischemic dog myocardium. Lab Invest 20:548-558.
43. Jonsson A, Hansson L. 1977. Prolonged exposure to a stressful stimulus (noise) as a cause of raised blood pressure in man. Lancet 1:86-88.
44. Kawecka-Jaszcz K. 1991. Effect of professional work and environmental factors on arterial blood pressure. Med Pract 42:291-296.
45. King DW, Gollnick PD. 1970. Ultrastructure of rat heart and liver after exhaustive exercise. Am J Physiol 218:1150-1155.
46. Komazaki S, Takada M, Clark NB. 1992. Ultrastructural localization of calcium in the chick chorioallantoic membrane as revealed by cytochemistry and X-ray microanalysis. Anat Embryol 186:529-535.
47. Kraicer J, Berand G, Lynwood DW. 1977. Pars intermedia ACTH and MSH contents: effects of adrenalectomy, gonadectomy and a neurotropic (noise) stress. Neuroendocrinology 23:352-367.
48. Kunchandy J, Kulkarni K. 1988. Hypoxic stress-induced convulsion and death: protective effect of α2-adrenoceptor and benzodiazepine receptor agonists and Ro 5-4864. Arch Int Pharmacodyn 292:35-44.
49. Laguens RP, Gomez-Dumm CL. 1967. Fine structure of myocardial mitochondria in rats after exercise for one-half to two hours. Circ Res 21:271-275.
50. Leeuwin RS, Zeegers A, van Wilgenburg H. 1993. Actions of benzodiazepines on the inotropy of the perfused rat heart. Arch Int Pharmacodyn 326:5-12.
51. Leeuwin RS, Zeegers A, van Wilgenburg H. 1996a. PK 11195 antagonizes the positive inotropic response of the isolated rat heart to diazepam but not the negative inotropic response. Eur J Pharmacol 299:149-152.
52. Leeuwin RS, Zeegers A, van Wilgenburg H. 1996b. Flunarizine but not theophylline modulates inotropic responses of the isolated rat heart to diazepam. Eur J Pharmacol 315:153-157.
53. Le Fur G, Guilloux F, Rufat P, Benavides J, Uzan A, Renault C, Dubroeucq MC, Guérémy C. 1983. Peripheral benzodiazepine binding sites: effect of PK 11195, 1-(2-chlorophenyl)-N-methyl-(1-methylpropyl)-3 isoquinolinecarboxamide. Life Sci 32:1849-1856.
54. Lenzi P, Gesi M, Martini F, Natale G, Pellegrini A, Soldani P, Paparelli A. 1998. Ultrastructure of rat atrial tissue after either perfusion- or immersion-fixation both in vivo and in vitro study: comparison of methodological reliability. Eur J Morphol 36:77-82.
55. Linden W, Franckish J, McEachern HM. 1985. The effect of noise interference type of cognitive stressors and order of task on cardiovascular activity. Int J Psychophysiol 3:67-74.
56. Lopes AC, Borotchin L, Sasso WS, DiDio LJA. 1992. Action of propranolol on the atrial cardiomyocytes of rats submitted to cold stress. J Submicrosc Cytol Pathol 24:187-191.
57. Lublin A, Wolfenson D, Berman A. 1995. Sex differences in blood flow distribution of normothermic and heat-stressed rabbits. Am J Physiol 268:66-71.
58. Maschke C, Breinl S, Grimm R, Ising H. 1993. The influence of noctural aircraft noise on sleep and on catecholamine secretion. Schriftenr Ver Wasser Boden Lufthyg 88:395-407.
59. Matlib MA, Lee SW, De Pover A, Schwartz A. 1983. A specific inhibitory action of certain benzothiazepines and benzodiazepines on the sodium-calcium exchange process of heart and brain mitochondria. Eur J Pharmacol 89:327-328.
60. Mestre M, Carriot T, Belin C, Uzan A, Renaud C, Dubroeucq MC, Gueremy C, Le Fur G. 1984. Electrophysiological and pharmacological characterization of peripheral benzodiazepine receptors in guinea-pig heart preparation. Life Sci 35:953-962.
61. 1-Receptor localization in rat heart and kidney using autoradiography. Am J Physiol 249:H512-H519.
62. Ninan PT, Insel TM, Cohen RM, Cook JM, Skolnick P, Paul SM. 1982. Benzodiazepine receptor-mediated experimental "anxiety" in primates. Science 218:1332-1334.
63. Papadopoulos V, Berkovich A, Krueger KE. 1991. The role of diazepam binding inhibitor and its processing products at mitochondrial benzodiazepine receptors: regulation of steroid biosynthesis. Neuropharmacology 30:1417-1423.
64. Papadopoulos V, Widmaier EP, Amri H, Zilz A, Li H, Culty M, Castello R, Philip GH, Sridaran R, Drieu K. 1998. In vivo studies on the role of the peripheral benzodiazepine receptor (PBR) in steroidogenesis. Endocr Res 24:479-487.
65. Paparelli A, Soldani P, Breschi MC, Martinotti E, Scatizzi R, Berrettini S, Pellegrini A. 1992. Effects of subacute exposure to noise on the noradrenergic innervation of the cardiovascular system in young and aged rats: a morphofunctional study. J Neural Transm 88:105-113.
66. Paparelli A, Pellegrini A, Lenzi P, Gesi M, Soldani P. 1995. Ultrastructural changes in atrial tissue of young and aged rats submitted to acute noise stress. J Submicrosc Cytol Pathol 27:137-142.
67. Parrot J, Petiot JC, Lobreau JP, Smolik HJ. 1992. Cardiovascular effects of impulse noise, road traffic noise, and intermittent pink noise at Laeq = 75 dB, as a function of sex, age, and level of anxiety: a comparative study. Heart rate data. Int Arch Occup 63:477-484.
68. Pellegrini A, Gesi M, Soldani P, Lenzi P, Paparelli A. 1995. Influence of diazepam on rat cardiac noradrenergic innervation in response to noise stress. In Vivo 9:211-214.
69. Pellegrini A, Soldani P, Gesi M, Lenzi P, Paparelli A. 1996. The action of diazepam on noise-induced alterations in rat atrial tissue: an ultrastructural study. J Submicrosc Cytol Pathol 28:507-512.
70. Ruiz F, Hernandez J, Perez D. 1989. The effect of diazepam on ventricular automaticity induced by a local injury. Evidence of involvement of "peripheral type" benzodiazepine receptors. J Pharm Pharmacol 41:306-310.
71. Salt PJ. 1972. Inhibition of noradrenaline uptake-2 in the isolated rat heart by steroids, clonidine and methoxylated phenylethylamines. Eur J Pharmacol 20:329-340.
72. Salvetti F, Chelli B, Gesi M, Pellegrini A, Giannaccini G, Lucacchini A, Martini C. 2000. Effect of noise exposure on rat cardiac peripheral benzodiazepine receptors. Life Sci 66:1165-1175.
73. Sawada Y. 1993. Hemodinamic effects of short-term noise exposure: comparison of steady state and intermittent noise at several sound pressure levels. Jpn Circ J 57:862-872.
74. Shany E, Hochhauser E, Halpern P, Vidne B, Gavish M, Geller E, Hasharoni A, Barak Y, Yakirevich V, 1994. Ro 5-4864 has a negative inotropic effect on human atrial muscle strips that is not antagonized by PK 11195. Eur J Pharmacol 253:231-236.
75. Singhal RL, Rastogi RB, Lapierre YD. 1983. Diazepam potentiates the effect of neuroleptics on behavioural activity as well as dopamine and norepinephrine turnover: Do benzodiazepines have antipsycotic potency? J Neural Transm 56:127-138.
76. Soldani P, Pellegrini A, Gesi M, Lenzi P, Cristofani R, Paparelli A. 1997a. SEM/TEM investigation on rat cardiac subcellular alterations induced by changing duration of noise stress. Anat Rec 248:521-532.
77. Soldani P, Pellegrini A, Gesi M, Natale G, Lenzi P, Martini F, Paparelli A. 1997b. Gender difference in noise stress-induced ultrastructural changes in rat myocardium. J Submicrosc Cytol Pathol 29: 527-536.
78. Sridaran R, Philip GH, Li H, Culty M, Liu Z, Stocco DM, Papadopoulos V. 1999. GnRH agonist treatment decreases progesterone synthesis, luteal peripheral benzodiazepine receptor mRNA, ligand binding and steroidogenic acute regulatory protein expression during pregnancy. J Mol Endocrinol 22:45-54.
79. 1-adrenoceptor densities in different mammalian species. Br J Pharmacol 107:185-188.
80. Tallman JF, Paul SM, Skolnick P, Gallager DW. 1980. Receptors for the age of anxiety: pharmacology of the benzodiazepines. Science 207:274-281.
81. 1-adrenoceptors: an overview. Pharmacol Rev 45:147-175.
82. Tomei F, Tomao E, Baccolo TP, Papaleo B, Alfi P. 1992. Vascular effects of noise. Angiology 43:904-912.
83. Tong Y, Rheaume E, Simard J, Pelletier G. 1991. Localization of peripheral benzodiazepine binding sites and diazepam-binding inhibitor (DBI) mRNA in mammary glands and dimethylbenz(a)antracene (DMBA)-induced mammary tumors in the rat. Regul Pept 33:263-273.
84. Weissler A, Kruger F, Baba N, Scarpelli D, Leighton R, Gallimore J. 1968. Role of anaerobic metabolism in the preservation of functional capacity and structure of anoxic myocardium. J Clin Invest 47:403-416.
85. Wiechman BE, Borowitz JL. 1979. Effect of steroid hormones and diethylstilbestrol on adrenomedullary catecholamine secretion. Pharmacology 18:195-210.
86. Zoratti M, Szabo I. 1995. The mitochondrial permeability transition. Biochim Biophys Acta 1241:139-176.
87. Zukowska-Grojec Z, Shen GH, Capraro PA, Vaz CA. 1991. Cardiovascular, neuropeptide Y, and adrenergic responses in stress are sexually differentiated. Physiol Behav 49:771-777.