The action of diazepam on noise-induced alterations in rat atrial tissue: An ultrastructural study

Journal of Submicroscopic Cytology and Pathology

Volumn 28, Issue 4, 1996, Pages 507-512

  Pellegrini, A ^a   Soldani, P ^a   Gesi, M ^a   Lenzi, P ^a   Paparelli, Antonio ^a,b  

^a UNIVERSITY OF PISA   (Italy)

^b Istituto di Anatomia Umana Normale   (Italy)

Author keywords

Atrium; Diazepam; Mitochondria; Noise stress; Rat; Ultrastructure

Indexed keywords

DIAZEPAM;

ANIMAL; ARTICLE; CYTOLOGY; DRUG EFFECT; HEART ATRIUM; MALE; MITOCHONDRION; MUSCLE FIBRIL; NOISE; PATHOLOGY; RAT; ULTRASTRUCTURE; WISTAR RAT;

ANIMALS; DIAZEPAM; HEART ATRIA; MALE; MITOCHONDRIA; MYOFIBRILS; NOISE; RATS; RATS, WISTAR;

EID: 0030253398     PISSN: 11229497     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. ALTURA B.M., ALTURA B.T., GEBREWOLD A., ISING H. and GUNTHER T., 1992. Noise-induced hypertension and magnesium in rats: relationship to microcirculation and calcium J. Appl. Physiol. 72, 194-202.
2. ANDREWS N., ZHARKOVSKY A. and FILE S.E., 1992. Acute handling stress downregulates benzodiazepine receptors: reversal by diazepam. Eur. J. Pharmacol., 210, 247-251.
3. ANHOLT R.R.H., 1986. Mitochondrial benzodiazepine receptors as potential modulators of intermediary metabolism. Trends Pharmacol. Sci., 8, 506-511.
4. BIGGIO G., CONCAS A., SERRA M., SALIS M., CORDA M.G., NARCHI V., CRISPON C. and GESSA G.L., 1984. Stress and β-carbolines decrease the density of low affinity GABA binding sites; an effect reversed by diazepam. Brain Res., 305, 13-18.
5. BRESCHI M.C., SCATIZZI R., MARTINOTTI E., PELLEGRINI A., SOLDANI P. and PAPARELLI A., 1994. Morphofunctional changes in the noradrenergic innervation of the rat cardiovascular system after varying duration of noise stress. Int. J. Neurosci., 75, 73-81.
6. BRESCHI M.C., MARTINI C., SCATIZZI R., CRISTOFANI R., GIANNACCINI G., MARTINOTTI E. and LUCACCHINI A., 1995. Benzodiazepine agonists reverse the effects of noise exposure on central benzodiazepine receptors and cardiac responsiveness. Life Sci., 557, 1131-1140.
7. DANIELL H.B., 1975. Cardiovascular effects of diazepam and chlordiazepoxide. Eur. J. Pharmacol., 32, 58-63.
8. DE SOUZA E.B., ANHOLT R.R.H., MURPHY K.M.M., SNYDER S.H. and KUHAR M.J., 1985. Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal and testis. Endocrinology, 116, 567-573.
9. DI MICCO J.A., 1987. Evidence for control of cardiac vagal tone by benzodiazepine receptors. Neuropharmacology, 26, 553-558.
10. ELGOYHEN B. and ADLER-GRASCHINSKY E., 1989. Diminution by benzodiazepines of the chronotropic responses to noradrenaline in rat isolated atria. Eur. J. Pharmacol., 164, 467-478.
11. FARES F., WEIZMAN A., ZLOTOGORSKI D. and GAVISH M., 1987. Ontogenetic development of peripheral benzodiazepine binding sites in rat brain, heart and lung. Brain Res., 408, 381-384.
12. GAMALLO A., ALARIO P., VILLANUA M.A. and NAVA M.P., 1988. Effect of chronic stress in the blood pressure in the rat: ACTH administration. Horm. Metab. Res., 20, 336-338.
13. GUE M., FIORAMONTI J., FREXINOS J., ALVINERIE M. and BUENO L., 1987. Influence of acoustic stress by noise on gastrointestinal motility in dogs. Dig Dis. Sci., 32, 1411-1417.
14. HAEFELY W., POLC P., PIERI L., SCHAFFNER R. and LAURENT J.P., 1983. Neuropharmacology of benzodiazepines; synaptic mechanisms and neural basis of action, In: The Benzodiazepines: from Molecular Biology to Clinical Practice'. Costa E. ed., Raven Press, New York, pp. 21-29.
15. LANE J.D., CRENSHAW C.M., GUERIN G.F., CHEKEK D.R. and SMITH J.E., 1982. Changes in biogenic amine and benzodiazepine receptors correlated with conditioned emotional response and its reversal by diazepam, Eur. J. Pharmacol., 83, 183-190.
16. LEAKE C.D., 1970. 'Physiological Effects of Noise'. Welch B.L. and Welch A.S. eds., Plenum Press, New York, pp. 337-340.
17. MATLIB M.A., LEE S.W., DE POVER A. and SCWARTZ A., 1983. A specific inhibitory action of certain benzothiazepines and benzodiazepines on the sodium-calcium exchange process of heart and brain mitochondria. Eur. J. Pharmacol., 89, 327-328.
18. MESTRE M., CARRIOT T., BELIN C., UZAN A., RENAUD C., DUBROEUCQ M.C., GUEREMY C. and LE FUR G., 1984. Electrophysiological and pharmacological characterization of peripheral benzodiazepine receptors in guinea-pig heart preparation. Life Sci., 35, 953-962.
19. NINAN P.T., INSEL T.M., COHEN R.M., COOK J.M., SKOLNICK P. and STEVEN M.P., 1982. Benzodiazepine receptor-mediated experimental anxiety in primates. Science, 218, 1332-1334.
20. PAPARELLI A., SOLDANI P., BRESCHI M.C., MARTINOTTI E., SCATIZZI R., BERRETTINI S. and PELLEGRINI A., 1992. Effects of subacute exposure to noise on the noradrenergic innervation of the cardiovascular system in young and aged rats: a morphofunctional study. J. Neural Tranam., 88, 105-113.
21. PAPARELLI A., PELLEGRINI A., LENZI P., GESI M. and SOLDANI P., 1995. Ultrastructural changes in atrial tissue of young and aged rats submitted to acute noise stress. J. Submicrosc. Cytol. Pathol., 27, 137-142.
22. PELLEGRINI A., GESI M., SOLDANI P., LENZI P. and PAPARELLI A., 1995. Influence of diazepam on rat cardiac noradrenergic innervation in response to noise stress. In Vivo, 9, 211-214.
23. SELYE H., 1979. Stress and cardiovascular disease. Cardoovasc. Med., 4, 183-187.
24. TALLMAN J.F., PAUL S.M., SHOLNICK P. and GALLADER D.W., 1980. Receptors for the age of anxiety: pharmacology of the benzodiazepines. Science, 207, 274-281.
25. TONG Y., TONON M.C., DESY L., NICOLAS P., VAUDRY H. and PELLETIER G., 1990. Localization of the endogenous benzodiazepine receptor ligand octadecaneuropeptide and peripheral type benzodiazepine receptors in the rat pituitary. J. Neuroendocrinol., 2, 189-192.
26. TONG Y., RHEAUME E., SIMARD J. and PELLETIER G., 1991. Localization of peripheral benzodiazepine-binding sites and diazepam-binding inhibitor (DBI) mRNA in mammary glands and dimethylbenz(a)-anthracene (DMBA)-induced mammary tumors in the rat. Regul. Peptides, 33, 263-273.
27. VOGEL W.H. and JENSH R., 1988. Chronic stress and plasma catecholamine and corticosterone levels in male rats. Neurosci. Lett., 87, 183-188.