Mutations in the extracellular domain and in the membrane-spanning domains interfere with nicotinic acetylcholine receptor maturation

Biochemistry

Volumn 41, Issue 41, 2002, Pages 12329-12335

  Yassin, Lina ^a   Samson, Abraham O ^b   Halevi, Sarah ^a   Eshel, Margalit ^a   Treinin, Millet ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

MUTATIONS;

BIOLOGICAL MEMBRANES; GENES; PROTEINS;

BIOCHEMISTRY;

MICROORGANISM PROTEIN; NICOTINIC RECEPTOR; PROTEIN DEG 3; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; IMMUNOHISTOCHEMISTRY; MALE; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; SCREENING;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS PROTEINS; EXTRACELLULAR SPACE; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION, MISSENSE; NERVE DEGENERATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTORS, NICOTINIC;

CAENORHABDITIS; CAENORHABDITIS ELEGANS; NEMATODA;

EID: 0037108067     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi020193y     Document Type: Article

References (22)

1. Numa, S., Noda, M., Takahashi, H., Tanabe, T., Toyosato, M., Furutani, Y., and Kikyotani, S. (1983) Cold Spring Harbor Symp. Quant. Biol. 48 (Part 1), 57-69.
2. Garcia-Guzman, M., Sala, F., Sala, S., Campos-Caro, A., and Criado, M. (1994) Biochemistry 33, 15198-15203.
3. Kreienkamp, H. J., Maeda, R. K., Sine, S. M., and Taylor, P. (1995) Neuron 14, 635-644.
4. Eertmoed, A. L., and Green, W. N. (1999) J. Neurosci. 19, 6298-6308.
5. Smith, M. M., Lindstrom, J., and Merlie, J. P. (1987) J. Biol. Chem. 262, 4367-4376.
6. Gu, Y., Forsayeth, J. R., Verrall, S., Yu, X. M., and Hall, Z. W. (1991) J. Cell Biol. 114, 799-807.
7. Keller, S. H., Lindstron, J., Ellisman, M., and Taylor, P. (2001) J. Biol. Chem. 276, 18384-18391.
8. Merlie, J. P., and Lindstrom, J. (1983) Cell 34, 747-757.
9. Treinin, M., and Chalfie, M. (1995) Neuron 14, 871-877.
10. Treinin, M., Gillo, B., Liebman, L., and Chalfie, M. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 15492-15495.
11. Halevi, S., McKay, J., Palfreyman, M., Yassin, L., Jorgensen, E., and Treinin, M. (2002) EMBO J. 21, 1012-1020.
12. Wood, W. B. (1988) The nematode Caenorhabditis elegans, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
13. Yassin, L., Gillo, B., Kahan, T., Halevi, S., Eshel, M., and Treinin, M. (2001) Mol. Cell. Neurosci. 17, 589-599.
14. Thompson, J. D., Higgins, D. G., and Gibson, T. J. (1994) Nucleic Acids Res. 22, 4673-4680.
15. Brejc, K., van Dijk, W. J., Klaassen, R. V., Schurmans, M., van Der Oost, J., Smit, A. B., and Sixma, T. K. (2001) Nature 411, 269-276.
16. Le Novre, N., and Changeux, J.-P. (1995-2000) http://www.pasteur.fr/recherche/banques/LGIC/catphylogen.html.
17. Bertrand, D., Galzi, J.-L., Devillers-Thiery, A., Bertrand, S., and Changeux, J.-P. (1993) Curr. Biol. 5, 688-693.
18. Blanton, M. B., and Cohen, J. B. (1994) Biochemisty 33, 2859-2872.
19. Hall, D. H., Gu, G., Garcia-Anoveros, J., Gong, L., Chalfie, M., and Driscoll, M. (1997) J. Neurosci. 17, 1033-1045.
20. Colley, N. J., Cassill, J. A., Baker, E. K., and Zuker, C. S. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 3070-3074.
21. De Stasio, E., Lephoto, C., Azuma, L., Holst, C., Stanislaus, D., and Uttam, J. (1997) Genetics 147, 597-608.
22. Torre, E. R., and Steward, O. (1996) J. Neurosci. 16, 5967-5978.