Characterization of Ca2+/calmodulin-dependent protein kinase I as a myosin II regulatory light chain kinase in vitro and in vivo

Biochemical Journal

Volumn 367, Issue 2, 2002, Pages 335-345

  Suizu, Futoshi ^a   Fukuta, Yasuaki ^a   Ueda, Kozue ^a   Iwasaki, Takahiro ^a   Tokumitsu, Hiroshi ^a   Hosoya, Hiroshi ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Actin filament; Phosphorylation; Stress fibre

Indexed keywords

MAPPING; PROTEINS; SIGNALING; STOICHIOMETRY;

PHOSPHORYLATION;

BIOCHEMISTRY;

1 (5 IODO 1 NAPHTHALENESULFONYL)HEXAHYDRO 1H 1,4 DIAZEPINE; 1 (5 IODONAPHTHALENE 1 SULFONYL)HOMOPIPERAZINE HYDROCHLORIDE; ACTIN; CALCIUM ION; MYOSIN; MYOSIN LIGHT CHAIN KINASE; MYOSIN LIGHT CHAIN KINASE INHIBITOR; PHOSPHOPEPTIDE; PROTEIN KINASE (CALCIUM,CALMODULIN); SERINE; UNCLASSIFIED DRUG; CALMODULIN DEPENDENT PROTEIN KINASE I; CALMODULIN-DEPENDENT PROTEIN KINASE I; MYOSIN II; MYOSIN LIGHT CHAIN;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL ORGANELLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; STOICHIOMETRY; ANIMAL; GENETICS; METABOLISM; MICROFILAMENT; MUTATION; PHOSPHORYLATION; ULTRASTRUCTURE;

ANIMALIA; MAMMALIA;

ACTINS; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; HELA CELLS; HUMANS; MICROFILAMENTS; MUTATION; MYOSIN LIGHT CHAINS; MYOSIN TYPE II; PEPTIDE MAPPING; PHOSPHORYLATION; SERINE;

EID: 0037107342     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020536     Document Type: Article

References (50)

1. McConkey, D. J. and Orrenius, S. (1999) Calcium in Programmed Cell Death (Carafoli, E. and Klee, C. B., eds.), pp. 596-609, Oxford University Press, New York
2. Means, A. R., Karl, C. R., Crenshaw, D. G. and Dayton, J. S. (1999) Traversing the Cell Cycle: The Calcium/Calmodulin Connection (Carafoli, E. and Klee, C. B., eds.) pp. 512-528, Oxford University Press, New York
3. Chin, D. and Means, A. R. (2000) Calmodulin: A prototypical calcium sensor. Trends Cell Biol. 10, 322-328
4. Soderling, T. R. and Stull, J. T. (2001) Structure and regulation of calcium/calmodulin-dependent protein kinases. Chem. Rev. 101, 2341-2352
5. 2+/calmodulin-dependent protein kinase IV. Identification of a brain CaM-kinase IV kinase. J. Biol. Chem. 269, 28640-28647
6. 2+-calmodulin-dependent protein kinase 1a. J. Biol. Chem. 269, 2158-2164
7. 2+/calmodulin-dependent protein kinase type Gr in rat cerebellar cortex. Proc. Natl. Acad. Sci. U.S.A. 88, 2850-2853
8. 2+/calmodulin-dependent protein kinase I from bovine brain. J. Biol. Chem. 262, 7273-7281
9. 2+-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 252, 1427-1430
10. Picciotto, M. R., Cohn, J. A., Bertuzzi, G., Greengard, P. and Nairn, A. C. (1992) Phosphorylation of the cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 267, 12742-12752
11. Lauffenburger, D. A. and Horwitz, A. F. (1996) Cell migration: A physically integrated molecular process. Cell 84, 359-369
12. Sellers, J. R. (2000) Myosins: A diverse superfamily. Biochim. Biophys. Acta 1496, 3-22
13. Tan, J. L., Ravid, S. and Spudich, J. A. (1992) Control of nonmuscle myosins by phosphorylation. Annu. Rev. Biochem. 61, 721-759
14. 2+/calmodulin-dependent protein kinase. Mol. Cell Biochem. 97, 87-98
15. Ebashi, S. (1976) A simple method of preparing actin-free myosin from smooth muscle. J. Biochem. (Tokyo) 79, 229-231
16. Murata-Hori, M., Mural, N., Komatsu, S., Uji, Y. and Hosoya, H. (1998) Concentration of singly phosphorylated myosin II regulatory light chain along the cleavage furrow of dividing HeLa cells. Biomed. Res. 19, 111-115
17. 2+/calmodulin-dependent protein kinase kinase. Role of the arg-pro-rich insert domain. J. Biol. Chem. 274, 15803-15810
18. 2+/calmodulin-dependent protein kinase kinase. J. Biol. Chem. 275, 20090-20095
19. 2+/calmodulin-dependent protein kinase cascade. Molecular cloning and expression of calcium/calmodulin-dependent protein kinase kinase. J. Biol. Chem. 270, 19320-19324
20. 2+/calmodulin-dependent protein kinase cascade in Caenorhabditis elegans. Implication in transcriptional activation. J. Biol. Chem. 274, 22556-22562
21. Tokumitsu, H. and Soderling, T. R. (1996) Requirements for calcium and calmodulin in the calmodulin kinase activation cascade. J. Biol. Chem. 271, 5617-5622
22. Murata-Hori, M., Fukuta, Y., Ueda, K., Iwasaki, T. and Hosoya, H. (2001) HeLa ZIP kinase induces diphosphorylation of myosin II regulatory light chain and reorganization of actin filaments in nonmuscle cells. Oncogene 20, 8175-8183
23. Suizu, F., Ueda, K., Iwasaki, T., Murata-Hori, M. and Hosoya, H. (2000) Activation of actin-activated MgATPase activity of myosin II by phosphorylation with MAPK. Activated protein kinase-1b (RSK-2). J. Biochem. (Tokyo) 128, 435-440
24. Sakurada, K., Seto, M. and Sasaki, Y. (1998) Dynamics of myosin light chain phosphorylation at Ser19 and Thr18/Ser19 in smooth muscle cells in culture. Am. J. Physiol. 274, C1563-C1572
25. 2+-independent phosphorylation of myosin in rat caudal artery and chicken gizzard myofilaments. J. Physiol. 516, 805-824
26. Gerashchenko, B. I., Ueda, K., Hino, M. and Hosoya, H. (2002) Phosphorylation at threonine-18 in addition to phosphorylation at serine-19 on myosin-II regulatory light chain is a mitosis-specific event. Cytometry 47, 150-157
27. Iwasaki, T., Murata-Hori, M., Ishitobi, S. and Hosoya, H. (2001) Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells. Cell Struct. Funct. 26, 677-683
28. Saitoh, M., Ishikawa, T., Matsushima, S., Naka, M. and Hidaka, H. (1987) Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase. J. Biol. Chem. 262, 7796-7801
29. Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J. (1951) Protein measurement with the folin-phenol reagents. J. Biol. Chem. 193, 265-275
30. Ohnishi, S. T. and Barr, J. K. (1978) A simplified method of quantitating protein using the biuret and phenol reagents. Anal. Biochem. 86, 193-200
31. Murata-Hori, M., Suizu, F., Iwasaki, T., Kikuchi, A. and Hosoya, H (1999) ZIP kinase identified as a novel myosin regulatory light chain kinase in HeLa cells. FEBS Lett. 451, 81-84
32. Ikebe, M. and Hartshorne, D. J. (1985) Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase. J. Biol. Chem. 260, 10027-10031
33. Haribabu, B, Hook, S. S., Selbert, M. A, Goldstein, E. G., Tomhave, E. D., Edelman, A. M., Snyderman, R. and Means, A. R. (1995) Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase. EMBO J. 14, 3679-3686
34. 2+/calmodulin-dependent protein kinase kinase. J. Biol. Chem. 273, 21473-21481
35. 2+/calmodulin-dependent protein kinase kinase isoforms. Biochemistry 40, 13925-13932
36. Katoh, K., Kano, Y., Amano, M., Kaibuchi, K. and Fujiwara, K. (2001) Stress fiber organization regulated by MLCK and Rho-kinase in cultured human fibroblasts. Am. J. Physiol. 280, C1669-C1679
37. Totsukawa, G., Yamakita, Y., Yamashiro, S., Hartshorne, D. J., Sasaki, Y. and Matsumura, F. (2000) Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts. J. Cell Biol. 150, 797-806
38. Petrache, I., Verin, A. D., Crow, M. T., Birukova, A., Liu, F. and Garcia, J. G. (2001) Differential effect of MLC kinase in TNF-alpha-induced endothelial cell apoptosis and barrier dysfunction. Am. J. Physiol. 280, L1168-L1178
39. Mansfield, P. J., Shayman, J. A. and Boxer, L. A. (2000) Regulation of polymorphonuclear leukocyte phagocytosis by myosin light chain kinase after activation of mitogen-activated protein kinase. Blood 95, 2407-2412
40. Bresnick, A. R. (1999) Molecular mechanisms of nonmuscle myosin-II regulation. Curr. Opin. Cell Biol. 11, 26-33
41. 2+-calmodulin-dependent kinase with myosin light chain phosphorylating activity. J. Biol. Chem. 261, 5389-5395
42. Chrzanowska-Wodnicka, M. and Burridge, K. (1996) Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J. Cell Biol. 133, 1403-1415
43. Poperechnaya, A., Varlamova, O., Lin, P. J, Stull, J. T. and Bresnick, A. R. (2000) Localization and activity of myosin light chain kinase isoforms during the cell cycle. J. Cell Biol. 151, 697-708
44. Yoneda, Y. (2000) Nucleocytoplasmic protein traffic and its significance to cell function. Genes Cells 5, 777-787
45. Nowak, G., Pestic-Dragovich, L., Hozak, P., Philimonenko, A., Simerly, C., Schatten, G. and de Lanerolle, P. (1997) Evidence for the presence of myosin I in the nucleus. J. Biol. Chem. 272, 17176-17181
46. 2+/calmodulin-dependent protein kinase kinases in the adult rat brain. Eur. J. Neurosci. 12, 89-99
47. Ueda, K., Murata-Hori, M., Tatsuka, M. and Hosoya, H. (2002) Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells. Oncogene 21, 5852-5860
48. Fluck, R. A., Miller, A. L. and Jaffe, L. F. (1991) Slow calcium waves accompany cytokinesis in medaka fish eggs. J. Cell Biol. 115, 1259-1265
49. Chang, D. C. and Meng, C. (1995) A localized elevation of cytosolic free calcium is associated with cytokinesis in the zebrafish embryo. J. Cell Biol. 131, 1539-1545
50. 2+/CaM-dependent protein kinases required for normal nuclear division in Aspergillus nidulans. J. Biol. Chem. 275, 38230-38238