Spx1, a novel X-linked homeobox gene expressed during spermatogenesis

Mechanisms of Development

Volumn 65, Issue 1-2, 1997, Pages 87-98

  Branford, William W ^a   Zhao, Guang Quan ^b   Valerius, M Todd ^a   Weinstein, Michael ^c   Birkenmeier, Edward H ^d   Rowe, Lucy B ^d   Potter, S Steven ^a  

^a CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d JACKSON LABORATORY   (United States)

Author keywords

Homeobox gene; Mouse Spermatogenesis; Testis; X chromosome

Indexed keywords

HOMEODOMAIN PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; EMBRYO; GENE EXPRESSION; HOMEOBOX; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; SPERMATID; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOGONIUM; TESTIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; HOMEODOMAIN PROTEINS; LINKAGE (GENETICS); MALE; MICE; MOLECULAR SEQUENCE DATA; PROTO-ONCOGENE PROTEINS; SPERMATOGENESIS; TRANSCRIPTION FACTORS; X CHROMOSOME;

ANIMALIA;

EID: 0031194261     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(97)00058-0     Document Type: Article

References (64)

1. Andersen, B., Pearse, R.V. II, Schlegel, P.N., Cichon, Z., Schonemann, M.D., Bardin, C.W. and Rosenfeld, M.G. (1993) Sperm 1: a POU-domain gene transiently expressed immediately before meiosis I in the male germ cell. Proc. Natl. Acad. Sci. USA 90, 11084-11088.
2. Bellvé, A.R., Cavicchia, J.C., Millette, C.F., O'Brien, D.A., Bhatnagar, Y.M. and Dym, M. (1977) Spermatogenic cells of the prepubertal mouse. Isolation and morphological characterization. J. Cell Biol. 74, 68-85.
3. Bradley, A., Evans, M., Kaufman, M.H. and Robertson, E. (1984) Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature 309, 255-256.
4. Braun, R.E., Behringer, R.R., Peschon, J.J., Brinster, R.L. and Palmiter, R.D. (1989) Genetically haploid spermatids are phenotypically diploid. Nature 337, 373-376.
5. Bürglin, T.R. (1994) A comprehensive classification of homeobox genes. In Duboule, D. (ed.), Guidebook to the Homeobox Genes, Oxford University Press, New York, pp. 25-72.
6. Caldwell, K.A. and Handel, M.A. (1991) Protamine transcript sharing among postmeiotic spermatids. Proc. Natl. Acad. Sci. USA 88, 2407-2411.
7. Chomczynski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol -chloroform extraction. Anal. Biochem. 162, 156-159.
8. Cserjesi, P., Lilly, B., Bryson, L., Wang, Y., Sassoon, D.A. and Olson, E.N. (1992) MHox: a mesodermally restricted homeodomain protein that binds an essential site in the muscle creatine kinase enhancer. Development 115, 1087-1101.
9. Dollé, P. and Duboule, D. (1989) Two gene members of the murine HOX-5 complex show regional and cell-type specific expression in developing limbs and gonads. EMBO J. 8, 1507-1515.
10. Frigerio, G., Burri, M., Bopp, D., Baumgartner, S. and Noll, M. (1986) Structure of the segmentation gene paired and the Drosophila PRD gene set as part of a gene network. Cell 47, 735-746.
11. Gehring, W.J. (1994) A history of the homeobox. In Duboule, D. (ed.), Guidebook to the Homeobox Genes, Oxford University Press, New York, pp. 1-10.
12. Gilbert, S.F. (1994) Developmental Biology. Sinauer Associates, Sunderland.
13. Gordon, D.F., Wagner, J., Atkinson, B.L., Chiono, M., Berry, R., Sikela, J. and Gutierrez-Hartmann, A. (1996) Human Cart-1: structural organization, chromosomal localization, and functional analysis of a cartilage-specific homeodomain cDNA. DNA Cell Biol. 15, 531-541.
14. Goulding, M.D., Chalepakis, G., Deutsch, U., Erselius, J.R. and Gruss, P. (1991) Pax-3, a novel murine DNA binding protein expressed during early neurogenesis. EMBO J. 10, 1135-1147.
15. Griswold, M.D. (1995) Interactions between germ cells and Sertoli cells in the testis. Biol. Reprod. 52, 211-216.
16. Han, K. and Manley, J.L. (1993) Transcriptional repression by the Drosophila Even-skipped protein: definition of a minimal repression domain. Genes Dev. 7, 491-503.
17. Handel, M.A. and Hunt, P.A. (1992) Sex-chromosome pairing and activity during mammalian meiosis. Bioessays 14, 817-822.
18. Hecht, N.B. (1993) Gene expression during male germ cell development. In Desjardins, C. and Ewing, L.L. (eds.), Cell and Molecular Biology of the Testis, Oxford University Press, New York, pp. 400-432.
19. Hendriksen, P.J.M., Hoogerbrugge, J.W., Themmen, A.P.N., Koken, M.H.M., Hoeijmakers, J.H.J., Oostra, B.A., Van Der Lende, T. and Grootegoed, J.A. (1995) Postmeiotic transcription of X and Y chromosomal genes during spermatogenesis in the mouse. Dev. Biol. 170, 730-733.
20. Jostes, B., Walther, C. and Gruss, P. (1990) The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system. Mech. Dev. 33, 27-37.
21. Kappen, C., Schughart, K. and Ruddle, F.H. (1989) Two steps in the evolution of Antennapedia-class vertebrate homeobox genes. Proc. Natl. Acad. Sci. USA 86, 5459-5463.
22. Kappen, C., Schughart, K. and Ruddle, F.H. (1993) Early evolutionary origin of major homeodomain sequence classes. Genomics 18, 54-70.
23. Kern, M.J., Witte, D.P., Valerius, M.T., Aronow, B.J. and Potter, S.S. (1992) A novel murine homeobox gene isolated by a tissue specific PCR cloning strategy. Nucleic Acids Res. 20, 5189-5195.
24. Kozak, M. (1987) An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15, 8125-8148.
25. Krumlauf, R. (1994) Box genes in vertebrate development. Cell 78, 191-201.
26. Kumari, M., Stroud, J.C., Anji, A., and McCarrey, J.R. (1996) Differential appearance of DNase I-hypersensitive sites correlates with differential transcription of Pgk genes during spermatogenesis in the mouse. J. Biol. Chem. 271, 14390-14397.
27. Li, H., Witte, D.P., Branford, W.W., Aronow, B.J., Weinstein, M., Kaur, S., Wert, S., Singh, G., Schreiner, C.M., Whitsett, J.A., Scott, W.J. Jr., and Potter, S.S. (1994) Gsh-4 encodes a LIM-type homeodomain, is expressed in the developing central nervous system and is required for early postnatal survival. EMBO J. 13, 2876-2885.
28. Lindsey, J.S. and Wilkinson, M.F. (1996a) Pem: A testosterone- and LH-regulated homeobox gene expressed in mouse Sertoli cells and epididymis. Dev. Biol. 179, 471-484.
29. Lindsey, S. and Wilkinson, M.F. (1996b) Homeobox genes and male reproductive development. J. Assist. Reprod. Genet. 13, 182-192.
30. Manly, K.F. (1993) A Macintosh program for storage and analysis of experimental genetic mapping data. Mamm. Genome 4, 303-313.
31. Matsui, Y., Zsebo, K.M. and Hogan, B.L. (1990) Embryonic expression of a haematopoietic growth factor encoded by the Sl locus and the ligand for c-kit. Nature 347, 667-669.
32. McCarrey, J.R. (1993) Development of the germ cell. In Desjardins, C. and Ewing, L.L. (eds.), Cell and Molecular Biology of the Testis, Oxford University Press, New York, pp. 58-89.
33. McGinnis, W. and Krumlauf, R. (1992) Homeobox genes and axial patterning. Cell 68, 283-302.
34. McKee, B.D. and Handel, M.A. (1993) Sex chromosomes, recombination, and chromatin conformation. Chromosoma 102, 71-80.
35. Meijlink, F., de Laaf, R., Verrijzer, P., Destrée, O., Kroezen, V., Hilkens, J. and Deschamps, J. (1987) A mouse homeobox containing gene on chromosome 11: sequence and tissue-specific expression. Nucleic Acids Res. 15, 6773-6786.
36. Mitchell, P.J. and Tjian, R. (1989) Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 245, 371-378.
37. Moss, S.B., VanScoy, H. and Gerton, G.L. (1997) Mapping of a haploid transcribed and translated sperm-specific gene to the mouse X chromosome. Mamm. Genome 8, 37-38.
38. Motro, B., van der Kooy, D., Rossant, J., Reith, A. and Bernstein, A. (1991) Contiguous patterns of c-kit and steel expression: analysis of mutations at the W and Sl loci. Development 113, 1207-1221.
39. Oakberg, E.F. (1956) A description of spermiogenesis in the mouse and its use in analysis of the cycle of the seminiferous epithelium and germ cell renewal. Am. J. Anat. 99, 391-413.
40. Odorisio, T., Mahadevaiah, S.K., McCarrey, J.R. and Burgoyne, P.S. (1996) Transcriptional analysis of the candidate spermatogenesis gene Ube1y and of the closely related Ube1x shows that they are coexpressed in spermatogonia and spermatids but are repressed in pachytene spermatocytes. Dev. Biol. 180, 336-343.
41. Opstelten, D.J.E., Vogels, R., Robert, B., Kalkhoven, E., Zwartkruis, F., de Laaf, L., Destrée, O.H., Deschamps, J., Lawson, K.A. and Meijlink, F. (1991) The mouse homeobox gene, S8, is expressed during embryogenesis predominantly in mesenchyme. Mech. Dev. 34, 29-41.
42. Peterson, R.L., Jacobs, D.F. and Awgulewitsch, A. (1992) Hox-3.6: isolation and characterization of a new murine homeobox gene located in the 5′ region of the Hox-3 cluster. Mech. Dev. 37, 151-166.
43. Poccia, D. (1994) Molecular Aspects of Spermatogenesis. R.G. Landes, Austin, Molecular Biology Intelligence Unit.
44. Ptashne, M. (1988) How eukaryotic transcriptional activators work. Nature 335, 683-689.
45. Rowe, L.B., Nadeau, J.H., Turner, R., Frankel, W.N., Letts, V.A., Eppig, J.T., Ko, M.S.H., Thurston, S.J. and Birkenmeier, E.H. (1994) Maps from two interspecific backcross DNA panels available as a community genetic mapping resource. Mamm. Genome 5, 253-274.
46. Russell, L.D., Ettlin, R.A., Hikim, A.P.S. and Clegg, E.D. (1990) Histological and Histopathological Evaluation of the Testis. Cache River Press, Clearwater.
47. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Plainview.
48. Schneitz, K., Spielmann, P. and Noll, M. (1993) Molecular genetics of aristaless, a prd-type homeo box gene involved in the morphogenesis of proximal and distal pattern elements in a subset of appendages in Drosophila. Genes Dev. 7, 114-129.
49. Shannon, M. and Handel, M.A. (1993) Expression of the Hprt gene during spermatogenesis: implications for sex-chromosome inactivation. Biol. Reprod. 49, 770-778.
50. Sharpe, P.T., Miller, J.R., Evans, E.P., Burtenshaw, M.D. and Gaunt, S.J. (1988) Isolation and expression of a new mouse homeobox gene. Development 102, 397-407.
51. Simeone, A., D'Apice, M.R., Nigro, V., Casanova, J., Graziani, F., Acampora, D. and Avantaggiato, V. (1994) Orthopedia, a novel homeobox-containing gene expressed in the developing CNS of both mouse and Drosophila. Neuron 13, 83-101.
52. Stein, S., Fritsch, R., Lemaire, L. and Kessel, M. (1996) Checklist: vertebrate homeobox genes. Mech. Dev. 55, 91-108.
53. Taylor, B.A. and Rowe, L. (1989) A mouse linkage testing stock possessing multiple copies of the endogenous ecotropic murine leukemia virus genome. Genomics 5, 221-232.
54. Treisman, J., Harris, E., Wilson, D. and Desplan, C. (1992) The homeodomain: a new face for the helix-turn-helix? Bioessays 14, 145-150.
55. Tres, L.L. (1977) Extensive pairing of the XY bivalent in mouse spermatocytes as visualized by whole-mount electron microscopy. J. Cell Sci. 25, 1-15.
56. Valarché, I., Tissier-Seta, J.P., Hirsch, M.R., Martinez, S., Goridis, C. and Brunet, J.F. (1993) The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype. Development 119, 881-896.
57. Vanden Heuvel, G.B., Quaggin, S.E. and Igarashi, P. (1996) A unique variant of a homeobox gene related to Drosophila cut is expressed in mouse testis. Biol. Reprod. 55, 731-739.
58. Walther, C. and Gruss, P. (1991) Pax-6, a murine paired box gene, is expressed in the developing CNS. Development 113, 1435-1449.
59. Watrin, F. and Wolgemuth, D.J. (1993) Conservation and divergence of patterns of expression and lineage-specific transcripts in orthologues and paralogues of the mouse Hox-1.4 gene. Dev. Biol. 156, 136-145.
60. Welch, J.E., Schatte, E.C., O'Brien, D.A. and Eddy, E.M. (1992) Expression of a glyceraldehyde 3-phosphate dehydrogenase gene specific to mouse spermatogenic cells. Biol. Reprod. 46, 869-878.
61. Wright, W.W. (1993) Cellular interactions in the seminiferous epithelium. In Desjardins, C. and Ewing, L.L. (eels.), Cell and Molecular Biology of the Testis, Oxford University Press, New York, pp. 377-399.
62. Zhao, G.Q. and Hogan, B.L. (1996) Evidence that mouse Bmp8a (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development. Mech. Dev. 57, 159-168.
63. Zhao, G.Q., Zhou, X., Eberspaecher, H., Solursh, M. and de Crombrugghe, B. (1993) Cartilage homeoprotein 1, a homeoprotein selectively expressed in chondrocytes. Proc. Natl. Acad. Sci. USA 90, 8633-8637.
64. Zhao, G.Q., Deng, K., Labosky, P.A., Liaw, L. and Hogan, B.L. (1996) The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse. Genes Dev. 10, 1657-1669.