Synthesis, conformational analysis and bioactivity of Lan-7, a lanthionine analog of TT-232

Journal of Peptide Science

Volumn 6, Issue 1, 2000, Pages 26-35

  Li, Haitao ^a,b   Jiang, Xiaohui ^a,c   Howell, Stephen B ^a   Goodman, Murray ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b AGOURON PHARMACEUTICALS INC   (United States)

^c ACCELRYS INC   (United States)

Author keywords

Antitumor; Apoptosis; Conformational analysis; Lanthionine; Sandostatin

Indexed keywords

DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLLYSYLCYSTEINYLTHREONINAMIDE 2,6 DISULFIDE; LAN 7; LANTHIONINE; OCTREOTIDE; SOMATOSTATIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CONTROLLED STUDY; DISULFIDE BOND; DRUG CONFORMATION; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OVARY CANCER; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELLS, CULTURED; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HEMATOPOIETIC STEM CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PEPTIDES, CYCLIC; SOMATOSTATIN; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

EID: 0033983444     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1387(200001)6:1<26::AID-PSC231>3.0.CO;2-6     Document Type: Article

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