Haplotyping and estimation of haplotype frequencies for closely linked biallelic multilocus genetic phenotypes including nuclear family information

Human Mutation

Volumn 17, Issue 4, 2001, Pages 289-295

  Rohde, K ^a   Fuerst, R ^b  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b German Genome Resource Center RZPD   (Germany)

Author keywords

Expectation maximization algorithm; Haplotype frequency estimation; Haplotyping; Nuclear family information; SNP

Indexed keywords

ALLELE; ARTICLE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MAPPING; GENETIC PREDISPOSITION; GENOME; HAPLOTYPE; HUMAN; HUMAN CELL; MULTIGENE FAMILY; POPULATION GENETICS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 0035065489     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/humu.26     Document Type: Article

References (8)

1. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
2. Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data
3. HAPLO: A program using the EM algorithm to estimate frequencies of multi-site haplotypes
4. Parametric and nonparametric linkage analysis: A unified multipoint approach
5. The TDT and other family based tests for linkage disequilibrium and association
6. Testing linkage disequilibrium between a disease and a marker locus
7. Transmission/disequilibrium tests using multiple tightly linked markers