Human host defense and cytokines in mycobacterial infectious diseases: Interleukin-18 cannot compensate for genetic defects in the interleukin-12 system [2]

Clinical Infectious Diseases

Volumn 35, Issue 2, 2002, Pages 210-212

  Verreck, Frank A W ^a   De Boer, Tjitske ^a   Hoeve, Marieke ^a   Van Dissel, Jaap T ^b   Sanal, Ozden ^c   Kurimoto, Masashi ^d   Ottenhoff, Tom H M ^a  

^a Building 1   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c HACETTEPE UNIVERSITY   (Turkey)

^d HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 12; INTERLEUKIN 18;

CELL KILLING; CELLULAR IMMUNITY; GENETIC DISORDER; HELPER CELL; HOST RESISTANCE; IMMUNE SYSTEM; LETTER; MACROPHAGE ACTIVATION; MYCOBACTERIOSIS; PRIORITY JOURNAL;

ADULT; CHILD; HUMANS; IMMUNITY, CELLULAR; INTERLEUKIN-12; INTERLEUKIN-18; MUTATION; MYCOBACTERIUM INFECTIONS; TUBERCULOSIS;

EID: 0037100418     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/341314     Document Type: Letter

References (6)

1. Novel human immunodeficiencies reveal the essential role of type-1 cytokines in immunity to intracellular bacteria
2. Interferon-γ and interleukin-12 pathway defects and human disease
3. The role of IL-18 in innate immunity
4. Interleukin-18 regulates both Th1 and Th2 responses
5. Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients
6. Residual type 1 immunity in patients genetically deficient for interleukin 12 receptor β1 (IL-12Rβ1): Evidence for an IL-12Rβ1-independent pathway of IL-12 responsiveness in human T cells