In vitro induction of cytochrome P450 2B1- and 3A1-mRNA and enzyme immunostaining in cryopreserved precision-cut rat liver slices

Toxicology

Volumn 176, Issue 3, 2002, Pages 187-193

  Glockner R ^a   Steinmetzer, P ^a   Lupp, A ^a   Danz, M ^a   Muller D ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Cryopreserved rat liver slices; Cytochrome P450; Induction; Phenobarbital; Pregnenolone 16 carbonitrile

Indexed keywords

16ALPHA CYANOPREGNENOLONE; CYTOCHROME P450; CYTOCHROME P450 2B1; CYTOCHROME P450 3A1; MESSENGER RNA; PHENOBARBITAL;

ANIMAL TISSUE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CRYOPRESERVATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIVER SLICE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CRYOPRESERVATION; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; IMMUNOHISTOCHEMISTRY; LIVER; MALE; MICROTOMY; MIXED FUNCTION OXYGENASES; PHENOBARBITAL; PREGNENOLONE CARBONITRILE; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 0037100093     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(02)00136-1     Document Type: Article

References (14)

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5. Cultures with cryopreserved hepatocytes: Applicability for studies of enzyme induction
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7. Monooxygenation, cytochrome P450-mRNA expression and other functions in precision-cut rat liver slices
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