Drug-resistant human lung cancer cells are more sensitive to selenium cytotoxicity: Effects on thioredoxin reductase and glutathione reductase

Biochemical Pharmacology

Volumn 63, Issue 10, 2002, Pages 1875-1884

  Björkhem Bergman, Linda ^a   Jönsson, Kerstin ^a   Eriksson, Lennart C ^a   Olsson, Jerker M ^a   Lehmann, Sören ^a   Paul, Christer ^a   Björnstedt, Mikael ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cancer; Doxorubicin; Drug resistance; Glutathione reductase; Selenium; Thioredoxin reductase

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; GLUTATHIONE REDUCTASE; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; SELENITE; SELENIUM; THIOREDOXIN REDUCTASE;

ARTICLE; CANCER CELL CULTURE; CELL STRAIN; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG RESISTANCE; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME METABOLISM; HUMAN; HUMAN CELL; LUNG CARCINOMA; LUNG TOXICITY; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION;

BLOTTING, WESTERN; CELL DIVISION; DRUG RESISTANCE, NEOPLASM; GLUTATHIONE REDUCTASE; HUMANS; LUNG NEOPLASMS; SODIUM SELENITE; THIOREDOXIN REDUCTASE (NADPH); TUMOR CELLS, CULTURED;

EID: 0037094345     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)00981-4     Document Type: Article

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