Clinical and screening implications of the I1307K adenomatous polyposis coli gene variant in Israeli Ashkenazi Jews with familial colorectal neoplasia: Evidence for a founder effect

Cancer

Volumn 94, Issue 10, 2002, Pages 2561-2568

  Rozen, Paul ^a,b   Naiman, Tova ^a   Strul, Hana ^a,b   Taussky, Philipp ^a   Karminsky, Nataly ^a   Shomrat, Ruth ^a   Samuel, Ziona ^a   Yaron, Yuval ^a,b   Orr Urtreger, Avi ^a,b  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

APC variant; Ashkenazi; Colorectal carcinoma; Founder effect; I1307K; Israeli Jews; Screening; Sephardi

Indexed keywords

ADENOMATOUS POLYP; ARTICLE; CANCER GENETICS; CANCER RISK; CANCER SCREENING; COLORECTAL CARCINOMA; ETHNOLOGY; HIGH RISK POPULATION; HUMAN; ISRAEL; MAJOR CLINICAL STUDY; PENETRANCE; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; FEMALE; FOUNDER EFFECT; GENES, APC; HUMANS; ISRAEL; JEWS; MALE; MIDDLE AGED; VARIATION (GENETICS);

EID: 0037093967     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.10529     Document Type: Article

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