The induction of systemic and mucosal immunity to protein vaccines delivered through skin sites exposed to UVB

Vaccine

Volumn 20, Issue 16, 2002, Pages 2116-2130

  Enioutina, Elena Y ^a   Visic, Dino M ^a   Daynes, Raymond A ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Antibody formation; Immunity; Mucosal immunity

Indexed keywords

CYCLIC AMP; HAEMOPHILUS INFLUENZAE TYPE B VACCINE; VITAMIN D;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; FEMALE; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; INJECTION SITE; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; RADIATION EXPOSURE; ULTRAVIOLET B RADIATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIBODY FORMATION; CYTOKINES; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FEMALE; IMMUNITY, MUCOSAL; IMMUNIZATION; IMMUNOGLOBULIN G; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; SKIN; VACCINES;

EID: 0037093633     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(02)00060-9     Document Type: Article

References (73)

1. Cell-mediated immunosuppressive mechanisms induced by UV radiation
2. Susceptibility to immunosuppression by ultraviolet B radiation in the mouse
3. Studies on the mechanism of systemic suppression of contact hypersensitivity by ultraviolet B radiation
4. Dose-responses for UV-induced suppression of various immune responses
5. Effects of UV radiation on tumor immunity
6. Phenotypic and physical characteristics of the lymphoid cells involved in the immunity to syngeneic UV-induced tumors
7. Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB
8. Analysis of the mechanism of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiation
9. Suppression of delayed and contact hypersensitivity responses in mice have different UV dose responses
10. Alteration of the immune response to Mycobacterium bovis BCG in mice exposed chronically to low doses of UV radiation
11. Suppression of antibody responses to topically applied antigens by ultraviolet light irradiation: Induction of phototolerance
12. Mechanisms in the suppression of tumor rejection produced in mice by repeated UV irradiation
13. Studies into the transplantation biology of ultraviolet light-induced tumors
14. Modification of immunological potential by ultraviolet radiation. Part II. Generation of suppresser cells in short-term UV-irradiated mice
15. Impact of UVB radiation on the epidermal cytokine network
16. Regulation of murine lymphokine production in vivo: Ultraviolet radiation exposure depresses IL-2 and enhances IL-4 production by T-cells through an IL-1-dependent mechanism
17. Induction of IL-10 gene expression in human keratinocytes by UVB exposure in vivo and in vitro
18. UVB irradiation modulates systemic immune responses by affecting cytokine production of antigen-presenting cells
19. Ultraviolet B radiation-induced production of interleukin 1α and interleukin 6 in a human squamous carcinoma cell line is wavelength-dependent and can be inhibited by pharmacological agents
20. + macrophages that infiltrate human epidermis after in vivo ultraviolet exposure potently produce IL-10 and represent the major secretory source of epidermal IL-10 protein
21. In human skin, UVB initiates early induction of IL-10 over IL-12 preferentially in the expanding dermal monocytic/macrophagic population
22. Differential modulation of human epidermal Langerhans cell maturation by ultraviolet B radiation
23. Reduction in number and morphologic alterations of Langerhans cells after UVB radiation in vivo are accompanied by an influx of monocytoid cells into the epidermis
24. Effects of UV on the migration and function of epidermal antigen-presenting cells
25. The effect of ultraviolet B irradiation and urocanic acid isomers on dendritic cell migration
26. Differential effects of UVA1 and UVB radiation on Langerhans cell migration in mice
27. Effects of ultraviolet radiation on murine epidermal Langerhans cells: Doses of ultraviolet radiation that modulate ICAM-1 (CD54) expression and inhibit Langerhans cell function cause delayed cytotoxicity in vitro
28. Further characterization of UVB radiation effects on Langerhans cells: Altered expression of the co-stimulatory molecules B7-1 and B7-2
29. Differential sensitivity of freshly isolated and cultured murine Langerhans cells to ultraviolet B radiation and chemical fixation
30. Ultraviolet light and dendritic cells
31. Effects of phototherapy on the production of cytokines by peripheral blood mononuclear cells and on systemic antibody responses in patients with psoriasis
32. Travel to sunny countries is associated with changes in immunological parameters
33. Modulation of immunity to Borrelia burgdorferi by ultraviolet irradiation: Differential effect on Th1 and Th2 immune responses
34. Induction of common mucosal immunity by hormonally immunomodulated peripheral immunization
35. Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow
36. Immunotherapeutic potential of tumor antigen-pulsed and unpulsed dendritic cells generated from murine bone marrow
37. Visualization of peptide-specific T-cell immunity and peripheral tolerance induction in vivo
38. In vivo behavior of peptide-specific T-cells during mucosal tolerance induction: Antigen introduced through the mucosa of the conjunctiva elicits prolonged antigen-specific T-cell priming followed by anergy
39. Haemophilus influenzae invasive disease in the United States, 1994-1995: Near disappearance of a vaccine-preventable childhood disease
40. Six years' follow-up after hepatitis A vaccination
41. Measles, mumps, and rubella - Vaccine use and strategies for elimination of measles, and congenital rubella syndrome and control of mumps: Recommendations of the Advisory Committee on Immunization Practices (ACIP)
42. The health and economic benefits associated with pneumococcal vaccination of elderly persons with chronic lung disease
43. The induction of systemic and mucosal immune responses following the subcutaneous immunization of mature adult mice: Characterization of the antibodies in mucosal secretions of animals immunized with antigen formulations containing a vitamin D3 adjuvant
44. Antigen-bearing langerhans cells in skin, dermal lymphatics and in lymph nodes
45. Exposure of UVB-sensitive mice to immunosuppressive doses of UVB in vivo fails to affect the accessory function or the phenotype of draining lymph node dendritic cells
46. Role of tumour necrosis factor-alpha in ultraviolet B light-induced dendritic cell migration and suppression of contact hypersensitivity
47. The induction of systemic and mucosal immune responses to antigen-adjuvant compositions administered into the skin: Alterations in the migratory properties of dendritic cells appears to be important for stimulating mucosal immunity
48. Vitamin D 1-α-hydroxylase
49. Identification and immune regulation of 25-hydroxyvitamin D-1-α-hydroxylase in murine macrophages
50. TGF-β1 regulation of dendritic cells
51. Review article: Local and systemic regulation of mucosal immunity
52. Exposure to low-dose ultraviolet radiation suppresses delayed-type hypersensitivity to herpes simplex virus in mice
53. Mechanisms of UVB-induced suppression of the immune response to Mycobacterium bovis Bacillus Calmette-Guerin: Role of cytokines on macrophage function
54. Keratinocyte-derived cytokines and UVB-induced immunosuppression
55. Studies of delayed systemic effects of ultraviolet B radiation (UVR) on the induction of contact hypersensitivity. Part 2. Evidence that interleukin-10 from UVR-treated epidermis is the critical mediator
56. Studies on delayed systemic effects of ultraviolet B radiation on the induction of contact hypersensitivity. Part 3. Dendritic cells from secondary lymphoid organs are deficient in interleukin-12 production and capacity to promote activation and differentiation of T helper type 1 cells
57. UV radiation and mouse models of herpes simplex virus infection
58. In vivo exposure to ultraviolet radiation enhances pathogenic effects of murine leukemia virus, LP-BM5, in murine acquired immunodeficiency syndrome
59. A rat cytomegalovirus infection model as a tool for immunotoxicity testing
60. Effects of ultraviolet radiation on the pathogenesis of Mycobacterium lepraemurium infection in mice
61. Effects of ultraviolet-B exposure on the resistance to Listeria monocytogenes in the rat
62. The effect of UV irradiation on infection of mice with Borrelia burgdorferi
63. UVB exposure-induced systemic modulation of Th1- and Th2-mediated immune responses
64. In vivo evidence that ultraviolet B-induced suppression of allergic contact sensitivity is associated with functional inactivation of Th1 cells
65. Ultraviolet B-irradiated antigen-presenting cells display altered accessory signaling for T-cell activation: Relevance to immune responses initiated in skin
66. Deficient Th1-type immune responses via impaired CD28 signaling in ultraviolet B-induced systemic immunosuppression and the restorative effect of IL-12
67. Reduced IL-12 production by monocytes upon ultraviolet-B irradiation selectively limits activation of T helper-1 cells
68. Neutrophils, differentiated macrophages and monocyte/macrophage antigen-presenting cells infiltrate murine epidermis after UV injury
69. The role of chemokines in the regulation of dendritic cell trafficking
70. Dendritic cell biology and regulation of dendritic cell trafficking by chemokines
71. Regulation of dendritic cell trafficking: A process that involves the participation of selective chemokines
72. Interleukin-10 does not affect phagocytosis of particulate antigen by bone marrow-derived dendritic cells but does impair antigen-presentation
73. 1,25-Dihydroxyvitamin D3 stimulates transforming growth factor-β1 synthesis by mouse renal proximal tubular cells