Increased frequency of the uncommon tumor necrosis factor-857T allele in british and dutch patients with sarcoidosis

American Journal of Respiratory and Critical Care Medicine

Volumn 165, Issue 8, 2002, Pages 1119-1124

  Grutters, Jan C ^a,b,c   Sato, Hiroe ^a,b,c   Pantelidis, Panagiotis ^a,b,c   Lagan, Anna L ^a,b,c   McGrath, Deirdre S ^a,b,c   Lammers, Jan Willem J ^a,b,c   Van Den Bosch, Jules M M ^a,b,c   Wells, Athol U ^a,b,c   Du Bois, Roland M ^a,b,c   Welsh, Kenneth I ^a,b,c,d  

^a ST ANTONIUS HOSPITAL   (Netherlands)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Cytokine; Polymorphism (genetics); Sarcoidosis; Tumour necrosis factor

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

ALLELE; ARTICLE; CAUCASIAN; CONTROLLED STUDY; GENE FREQUENCY; GENE FUNCTION; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIABILITY; HUMAN; LOFGREN SYNDROME; LUNG DISEASE; LUNG SARCOIDOSIS; MAJOR CLINICAL STUDY; NETHERLANDS; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PRIORITY JOURNAL; PROMOTER REGION; SINGLE STRAND CONFORMATION POLYMORPHISM; UNITED KINGDOM;

EID: 0037090431     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.165.8.200110-0320     Document Type: Article

References (32)

1. Diffuse lung disease: Product of genetic susceptibility and environmental encounters
2. Sarcoidosis: Genes and microbes - Soil or seed?
3. Sarcoidosis: Do our genes really matter?
4. Cytokines in sarcoidosis
5. Sarcoidosis immunopathogenetic concepts and their clinical application
6. Tumour necrosis factor alpha restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice
7. The inducing role of tumour necrosis factor in the development of bactericidal granulomas during BCG infection
8. Th1 cytokine pattern in sarcoidosis is expressed by bronchoalveolar CD4+ and CD8+ T cells
9. Sarcoidosis: TNF-alpha release from alveolar macrophages and serum level of sIL-2R are prognostic markers
10. Alveolar macrophage TNF-α release and BAL cell phenotypes in sarcoidosis
11. Functional consequences of a polymorphism affecting NF-kappaB p50-p50 binding to the TNF promoter region
12. Tumour necrosis factor (TNF) gene polymorphism influences TNF-alpha production in lipopolysaccharide (LPS)-stimulated whole blood cell culture in healthy humans
13. Polymorphism of the human TNF-alpha promoter-random variation or functional diversity?
14. Identification of three new single nucleotide polymorphisms in the human tumour necrosis factor-alpha gene promoter
15. Single base polymorphism in the human tumour necrosis factor alpha (TNF alpha) gene detectable by NcoI restriction of PCR product
16. The -308 tumour necrosis factor-alfa promoter polymorphism effects transcription
17. Effects of a polymorphism in the human tumour necrosis factor alpha promoter on transcriptional activation
18. Polymorphism in tumour necrosis factor genes associated with mucocutaneous leishmaniasis
19. Tumour necrosis factor promoter polymorphism and susceptibility to lepromatous leprosy
20. Scarring trachoma is associated with polymorphism in the tumour necrosis factor alpha (TNF-alpha) gene promoter and with elevated TNF-alpha levels in tear fluid
21. Polymorphisms at position -308 in the promoter region of the TNF-α and in the first intron of the TNF-β genes and spontaneous and lipopolysaccharide-induced TNF-α release in sarcoidosis
22. Tumour necrosis factor alpha promoter gene polymorphism in sarcoidosis
23. Tumour necrosis factor-α promoter polymorphism in erythema nodosum
24. Polymorphism of the 5′-flanking region of the human tumour necrosis factor (TNF)-alpha gene in Japanese
25. TNF-238A promoter polymorphism contributes to susceptibility to ankylosing spondylitis in HLA-B27 negative patients
26. Statement on sarcoidosis. Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999
27. Polymerase chain reaction haplotyping using 3′ mismatches in the forward and reverse primers: Application to the biallelic polymorphisms of tumour necrosis factor and lymphotoxin α
28. Phototyping: Comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 & DQB1 by PCR with 144 primer mixes utilizing sequence-specific primers (PCR-SSP)
29. Interstitial lung diseases: An epidemiological overview
30. HLA-DR predicts the prognosis in Scandinavian patients with pulmonary sarcoidosis
31. An allelic polymorphism within the human tumour necrosis factor alpha promoter region is strongly associated with HLA A1, B8, and DR3 alleles