Diffuse lung disease: Product of genetic susceptibility and environmental encounters

Thorax

Volumn 52, Issue 1, 1997, Pages 92-94

  Lympany, P A ^a   Du Bois, R M ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

berylliosis; diffuse lung disease; genetic predisposition; sarcoidosis; scleroderma

Indexed keywords

ARTICLE; GENETIC SUSCEPTIBILITY; GRANULOMA; HUMAN; INTERSTITIAL LUNG DISEASE; LUNG FIBROSIS; LUNG INJURY; MORBIDITY; MORTALITY; PRIORITY JOURNAL;

EID: 0031033609     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.52.1.92     Document Type: Article

References (12)

1. Ghosh S, Collins FS. The geneticist's approach to complex disease. Annu Rev Med 1996;47:333-53.
2. Richeldi L, Sorrentino R, Saltini C. HLA-DPB1 glutamate 69: a genetic marker of beryllium disease. Science 1993; 262:242-4.
3. Martinetti M, Tinelli C, Kolek V, Cuccia M, Salvaneschi L, Pasturenzi, et al. The "sarcoidosis map": a joint survey of clinical and immunogenetic findings in two European countries. Am J Respir Crit Care Med 1995;152:557-64.
4. Lympany PA, Petrek M, Southcott AM, Newman Taylor AJ, Welsh KI, du Bois RM. HLA-DPB polymorphisms: Glu 69 association with sarcoidoisis. Eur J Immunogenet 1996;23:353-9.
5. Grunewald J, Janson CH, Eklund A, Ohrn M, Olerup O, Persson U, et al. Restricted V alpha 2.3 gene usage by CD4+ T lymphocytes in bronchoalveolar lavage fluid from sarcoidosis patients correlates with HLA-DR3. Eur J Immunol 1992;22:129-35.
6. Briggs DC, Vaughan RW, Welsh KI, Myers A, du Bois RM, Black CM. Immunogenetic prediction of pulmonary fibrosis in systemic sclerosis. Lancet 1991;338:661-2.
7. Vargas-Alarcon G, Granados J, Ibanez de Kasep G, Alcocer-Vardela J, Alarcon-Segovia D. Association of HLA-DR5 (DR11) with systemic sclerosis (scleroderma) in Mexican patients. Clin Exp Rheum 1995;13:11-6.
8. McHugh NJ, Whyte J, Artlett C, Briggs DC, Stephens CO, Olsen NJ, et al. Anti-centromere antibodies (ACA) in systemic sclerosis patients and their relatives: a serological and HLA study. Clin Exp Immunol 1994;96:267-74.
9. Kuwana M, Okano Y, Kaburaki J, Inoko H. HLA class II genes associated with anticentromere antibody in Japanese patients with systemic sclerosis (scleroderma). Ann Rheum Dis 1995;54:983-7.
10. Vazquez-Abad D, Rothfield NF. Autoantibodies in systemic sclerosis. Int Rev Immunol 1995;12:145-57.
11. Black CM, Welsh KI. Genetics of scleroderma. Clin Dermatol 1994;12:337-47.
12. Curiel DT, Pilewski JM, Albelda SM. Gene therapy approaches for inherited and acquired lung diseases. Am J Respir Cell Mol Biol 1996;14:1-18.