AT1 receptor blockade with losartan during gestation in Wistar rats leads to an increase in thirst and sodium appetite in their adult female offspring

Regulatory Peptides

Volumn 105, Issue 1, 2002, Pages 47-57

  Butler, D G ^a   Pak, S H ^a   Midgely, A ^a   Nemati, B ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Gestation; Losartan effects on offspring; Sodium appetite; Thirst; Wistar rats

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ELECTROLYTE; LOSARTAN; SODIUM CHLORIDE; WATER;

ADAPTATION; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ELECTROLYTE BLOOD LEVEL; FEMALE; FLUID INTAKE; GESTATIONAL AGE; HEMATOCRIT; KIDNEY FUNCTION; MALE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROGENY; RAT; RAT STRAIN; RECEPTOR BLOCKING; RECEPTOR UPREGULATION; SODIUM APPETITE; SODIUM INTAKE; THIRST; URINARY EXCRETION;

AGING; ANIMALS; APPETITE; BLOOD PRESSURE; BODY WEIGHT; CAROTID ARTERIES; DRINKING; EATING; ELECTROLYTES; FEMALE; KIDNEY; LOSARTAN; MALE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, ANGIOTENSIN; SODIUM; THIRST; TIME FACTORS;

RATTUS NORVEGICUS; SIGANUS;

EID: 0037089791     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(01)00380-9     Document Type: Article

References (48)

1. Comparison of the transplacental transfer of enalapril, captopril and losartan in sheep
2. Toxikinetic analysis of losartan during gestation and lactation in the rat
3. Angiotensin as dipsogen
4. Peptides, thirst and sodium appetite
5. Angiotensin, thirst and sodium appetite
6. Angiotensin-induced drinking: A model of peptidergic control of behaviour
7. 1 receptor antagonist losartan inhibits thirst but not sodium appetite in cattle
8. Role of aldosterone in sodium retention of pregnancy in the rat
9. Water homeostasis and vasopressin secretion during gestation
10. Circulatory adaptation to pregnancy-serial studies of hemodynamics, blood volume, renin and aldosterone in the baboon (Papio hamadryas)
11. Increased sodium chloride appetite during pregnancy in the rat
12. Angiotensin II inhibition on blood pressure and renal hemodynamics in pregnant rats
13. Renal hemodynamics and volume homeostasis in pregnancy
14. Evidence that systemic relaxin promotes moderate water consumption in late pregnancy in rats
15. Study of aldosterone levels in plasma during pregnancy
16. Sequential changes in the renin-angiotensin-aldosterone system and plasma progesterone concentration in normal and abnormal human pregnancy
17. Studies of the renin-angiotensin-aldosterone system, cortisol, DOC and ADH in normal and hypertensive pregnancy
18. Ovarian steroid regulation of angiotensin II-induced water intake in the rat
19. Production and physiological effects of progesterone metabolites in pregnant and pseudo pregnant rats
20. Sodium balance during pregnancy in the rat
21. 4
22. Role of central mineralocorticoid receptors in cardiovascular disease
23. Increased salt appetite in adrenalectomized rats
24. Role of renin-angiotensin system in blood pressure regulation in pregnancy
25. Maternal hypertension and progeny blood pressure: Role of aldosterone and 11 beta-HSD
26. Relationship between plasma renin, renin-substrate, angiotensin II, aldosterone, and electrolytes in normal pregnancy
27. Angiotensin II induces cellular hypertrophy in cultured urine proximal tubular cells
28. The renin-angiotensin-aldosterone system in mother and fetus at term
29. Effects of systemic treatment with irbesartan and losartan on central responses to angiotensin II in conscious normotensive rats
30. Blockade of central angiotensin II type 1 and type 2 receptors suppresses adrenalectomy-induced NaCl intake in rats
31. 1 receptor antagonists to cross the blood-brain barrier in rats
32. 2 receptors in the pregnant and non-pregnant sheep uterus
33. Reduced sensitivity of the renal circulation to angiotensin II in pregnant rats
34. Angiotensin II receptor alterations during pregnancy in rabbits
35. Angiotensin II receptor subtypes in the adrenals of pregnant rats
36. 1-selective angiotensin II receptor antagonist losartan in rats
37. 1-selective angiotensin II receptor antagonist losartan in rats
38. Increased sodium appetite in the rat induced by intracranial administration of components of the renin-angiotensin system
39. Dose-response analysis of angiotensin- and renin-induced drinking in the cat
40. Arousal of a specific and persistent sodium appetite in the rat with continuous intracerebro-ventricular infusion of angiotensin II
41. Exaggerated salt appetite of spontaneously hypertensive rats is decreased by central angiotensin-converting enzyme blocks
42. The effects of a converting enzyme inhibitor (captopril) and angiotensin II on fetal renal circulation
43. The effect of captopril (SQ14, 225) upon mother and foetus in the chronically cannulated ewe and in the pregnant rabbit
44. 1 receptor in the rat
45. Renin-angiotensin system in neonatal rats: Induction of a renal abnormality in response to ACE inhibition or angiotensin II antagonism
46. Peripheral angiotensin causes salt appetite in rats