Functional evidence for the ability of angiotensin AT1 receptor antagonists to cross the blood-brain barrier in rats

European Journal of Pharmacology

Volumn 307, Issue 3, 1996, Pages 259-267

  Polidori, Carlo ^a   Ciccocioppo, Roberto ^a   Pompei, Pierluigi ^a   Cirillo, Rocco ^b,c   Massi, Maurizio ^a  

^a UNIVERSITY OF CAMERINO   (Italy)

^b Laboratori Guidotti SpA   (Italy)

^c Menarini Ricerche SpA   (Italy)

Author keywords

Angiotensin AT1 receptor antagonist; Angiotensin II induced drinking; Blood brain barrier; EXP3174; GR117289; Losartan; LR B 081

Indexed keywords

2 BUTYL 4 CHLORO 1 [[2' (1H TETRAZOL 5 YL) 4 BIPHENYLYL]METHYL] 5 IMIDAZOLECARBOXYLIC ACID; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; LOSARTAN; LRB 081; UNCLASSIFIED DRUG; ZOLASARTAN;

ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG PENETRATION; DRUG POTENCY; DRUG TRANSPORT; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MEMBRANE TRANSPORT; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

EID: 0030568704     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00270-1     Document Type: Article

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