Diabetes impairs the enzymatic disposal of 4-hydroxynonenal in rat liver

Free Radical Biology and Medicine

Volumn 32, Issue 4, 2002, Pages 350-359

  Traverso, Nicola ^a,c   Menini, Stefano ^a   Odetti, Patrizio ^b   Pronzato, M Adelaide ^a   Cottalasso, Damiano ^a   Marinari, Umberto M ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c Department of Experimental Medicine   (Italy)

Author keywords

4 Hydroxynonenal (HNE); Alcohol dehydrogenase (ADH); Aldehyde dehydrogenase (ALDH); Diabetes; Free radicals; Glutathione S transferase (GST); Lipid peroxidation; Lipohydroperoxides; Microsomes; Mitochondria

Indexed keywords

4 HYDROXYNONENAL; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; ENZYME INHIBITOR; GLUTATHIONE TRANSFERASE; LIPID HYDROPEROXIDE; REACTIVE OXYGEN METABOLITE; 4-HYDROXY-2-NONENAL; ALDEHYDE; HYDROGEN PEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME METABOLISM; HYPERGLYCEMIA; HYPOXIA; LIPID LIVER LEVEL; LIPID PEROXIDATION; LIPID STORAGE; LIVER INJURY; LIVER MICROSOME; LIVER MITOCHONDRION; LIVER TOXICITY; MALE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; ANIMAL; DISEASE MODEL; DRUG DETOXIFICATION; GLUCOSE BLOOD LEVEL; LIVER; METABOLISM; MITOCHONDRION; SPECTROPHOTOMETRY;

ALDEHYDES; ANIMAL; BLOOD GLUCOSE; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; LIPID PEROXIDATION; LIVER; MALE; METABOLIC DETOXICATION, DRUG; MICROSOMES, LIVER; MITOCHONDRIA; RATS; SPECTROPHOTOMETRY; SUPPORT, NON-U.S. GOV'T; ANIMALS;

EID: 0037082353     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00811-5     Document Type: Article

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