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Volumn 277, Issue 24, 2002, Pages 21906-21912

Kinetic and structural basis of reactivity of pentaerythritol tetranitrate reductase with NADPH, 2-cyclohexenone, nitroesters, and nitroaromatic explosives

(8) Khan, Huma a,b,c Harris, Richard J a,b,c Barna, Terez a,b,c Craig, Daniel H a,b,c Bruce, Neil C a,b,c Munro, Andrew W a,b,c Moody, Peter C E a,b,c Scrutton, Nigel S a,b,c

a UNIVERSITY OF LEICESTER (United Kingdom)

b UNIVERSITY OF CAMBRIDGE (United Kingdom)

c UNIVERSITY OF EDINBURGH (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME ACTIVITY; REDOX POTENTIOMETRY;

COENZYMES; ESTERS; EXPLOSIVES; KETONES; REDOX REACTIONS; SPECTROPHOTOMETRY; X RAY CRYSTALLOGRAPHY;

ENZYME KINETICS;

2 CYCLOHEXENONE; 2,4 DINITROPHENOL; AROMATIC NITRO COMPOUND; NITROESTER; PENTAERYTHRITOL TETRANITRATE REDUCTASE; PENTAERYTHRITYL TETRANITRATE; PICRIC ACID; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRINITROTOLUENE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; ENZYME ACTIVITY; ENZYME STRUCTURE; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; REDUCTION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

CARBON; CYCLOHEXANONES; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; ESTERS; KINETICS; LIGANDS; MODELS, CHEMICAL; MODELS, MOLECULAR; NADP; NITROGEN; OXIDATION-REDUCTION; OXIDOREDUCTASES; PICRATES; PROTEIN BINDING; SPECTROPHOTOMETRY; TIME FACTORS; TRINITROTOLUENE;

EID: 0037077313 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M200637200 Document Type: Article

Times cited : (74)

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