Crystal structure of pentaerythritol tetranitrate reductase: "Flipped" binding geometries for steroid substrates in different redox states of the enzyme

Journal of Molecular Biology

Volumn 310, Issue 2, 2001, Pages 433-447

  Barna, Teréz M ^a   Khan, Huma ^a   Bruce, Neil C ^b   Barsukov, Igor ^a   Scrutton, Nigel S ^a   Moody, Peter C E ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Flavoenzyme; Old yellow enzyme; Pentaerythritol tetranitrate reductase; Steroid binding; barrel

Indexed keywords

ANDROSTANE DERIVATIVE; AROMATIC NITRO COMPOUND; BOLDIONE; DEUTERIUM; EXPLOSIVE; NITRIC ACID DERIVATIVE; OXIDOREDUCTASE; PENTAERYTHRITYL TETRANITRATE; PREDNISONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; STEROID; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STRUCTURE; ESCHERICHIA COLI; GEOMETRY; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 0035816226     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4779     Document Type: Article

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