Dorsal and ventral hippocampal cholinergic systems modulate anxiety in the plus-maze and shock-probe tests

Brain Research

Volumn 949, Issue 1-2, 2002, Pages 60-70

  Degroot, Aldemar ^a   Treit, Dallas ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Acetylcholine; Dorsal hippocampus; Fear; Plus maze; Shock probe; Ventral hippocampus

Indexed keywords

CHOLINESTERASE INHIBITOR; PHYSOSTIGMINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; CHOLINERGIC STIMULATION; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DRUG EFFECT; HIPPOCAMPUS; MALE; MAZE TEST; NONHUMAN; PAIN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; RAT; STIMULUS RESPONSE; TASK PERFORMANCE;

ACETYLCHOLINE; ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; CHOLINERGIC FIBERS; CHOLINESTERASE INHIBITORS; FEAR; HIPPOCAMPUS; MALE; MAZE LEARNING; PHYSOSTIGMINE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0037072512     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)02965-7     Document Type: Article

References (63)

1. Amaral D.G., Witter M.P. Hippocampal formation. Paxinos G., The Rat Nervous System. 1995;443-493 Academic Press, San Diego, CA.
2. Argyropoulos S.V., Sanford J.J., Nutt D.J. The psychobiology of anxiolytic drugs. Part 2: pharmacological treatments of anxiety. Pharmacol. Ther. 88:2000;213-227.
3. Azmitia E.C., Segal M. An autoradiographic analysis of the differential ascending projections of the dorsal and raphe nuclei in the rat. J. Comp. Neurol. 179:1978;641-668.
4. Bhatnagar S., Costall B., Smythe J.W. Hippocampal cholinergic blockade enhances hypothalamic-pituitary-adrenal responses to stress. Brain Res. 766:1997;244-248.
5. Bourin M., Hascoet M. Drug mechanisms in anxiety. Curr. Opin. Invest. Drugs. 2:2001;259-265.
6. Brioni J.D., O'Neill A.B., Kim D.J.B., Buckley M.J., Decker M.W., Americ S.P. Nicotinic receptor agonists exhibit anxiolytic-like effects on the elevated plus-maze test. Eur. J. Pharmacol. 238:1993;1-8.
7. Cummings J.L., Kaufer D. Neuropsychiatric aspects of Alzheimer's disease: the cholinergic hypothesis revisited. Neurology. 47:1996;876-883.
8. De Boer S.F., Slangen J.L., Van der Gugten J. Plasma catecholamine and corticosterone levels during active and passive shock probe avoidance in rats: Effects of chlordiazepoxide. Pharmacol. Biochem. Behav. 47:1990;1089-1098.
9. Decker M.W., Brioni J.D., Sullivan J.P., Buckley M.J., Radek R.J., Raszkiewicz J.L., Kang D.J.B., Giardina W.J., Wasicak J.T., Garvey D.S., Williams M., Americ S. (S)-3-Methyl-5(1-methyl-2-pyrrolidynyl)isoxazole (ABT 418): a novel cholinergic ligand with cognition enhancing and anxiolytic activities: II. In vivo characterisation. J. Pharmacol. Exp. Ther. 270:1994;319-328.
10. Degroot A., Kashluba S., Treit D. Septal GABAergic and hippocampal cholinergic systems modulate anxiety in the plus-maze and shock-probe tests. Pharmacol. Biochem. Behav. 69:2001;391-399.
11. Drugan R.C., Skolnick P., Paul S.M., Crawley J.N. Low doses of muscimol produce anticonflict actions in the lateral septum of the rat. Neuropharmacology. 25:1986;203-205.
12. Fadda F., Cocco S., Stancampiano R. Hippocampal acetylcholine release correlates with spatial learning performance in freely moving rats. Neuroreport. 11:2000;2265-2269.
13. Faraday M.M., Scheufele P.M., Rahman M.A., Grunberg N.E. Effects of chronic nicotine administration on locomotion depend on rat sex and housing condition. Nicotine Tob. Res. 1:1999;143-151.
14. Farr S.A., Flood J.F., Morley J.E. The effect of cholinergic, GABAergic, serotonergic, and glutamatergic receptor modulation on posttrial memory processing in the hippocampus. Neurobiol. Learn. Mem. 73:2000;150-167.
15. Felix R., Levin E.D. Nicotinic antagonist administration into the ventral hippocampus and spatial working memory in rats. Neuroscience. 81:1997;1009-1017.
16. File S.E., Gonzalez L.E., Andrews N. Comparative study of pre- and postsynaptic 5-HT1A receptor modulation of anxiety in two ethological animal tests. J. Neurosci. 16:1996;4810-4815.
17. File S.E., Gonzalez L.E. Anxiolytic effects in the plus maze of 5-HT1A receptor ligands in dorsal raphe and ventral hippocampus. Pharmacol. Biochem. Behav. 54:1996;123-128.
18. File S.E., Kenny P.J., Ougazzal A.M. Bimodal modulation by nicotine of anxiety in the social interaction test; role of the dorsal hippocampus. Behav. Neurosci. 112:1998;1423-1429.
19. File S.E., Gonzalez L.E., Andrews N. Endogenous acetylcholine in the dorsal hippocampus reduces anxiety through actions on nicotinic and muscarinic receptors. Behav. Neurosci. 112:1998;352-359.
20. Hess C., Blozovski D. Hippocampal muscarinic cholinergic mediation of spontaneous alternation and fear in the developing rat. Behav. Brain Res. 24:1987;203-214.
21. Hogg S., Andrews N., File S.E. Contrasting behavioural effects of 8-OH DPAT in the dorsal raphe nucleus and ventral hippocampus. Neuropharmacology. 33:1994;343-348.
22. Irvine E.E., Cheeta S., File S.E. Time course of changes in the social interaction test of anxiety following acute and chronic administration of nicotine. Behav. Pharmacol. 10:1999;691-697.
23. Jarvik M.E., Caskey N.H., Rose J.E., Herskovic J.E., Sadeghpour M. Anxiolytic effects of smoking associated with four stressors. Addict. Behav. 14:1989;379-386.
24. Johnston A.L., File S.E. Yohimbine's anxiogenic action: evidence for noradrenergic and dopaminergic sites. Pharmacol. Biochem. Behav. 32:1989;151-156.
25. Kopf S.R., Buchholzer M.L., Hilgert M., Loffelholz K., Klein J. Glucose plus choline improve passive avoidance behaviour and increase hippocampal acetylcholine release in mice. Neuroscience. 103:2001;365-371.
26. Lehmann O., Jeltsch H., Lehnardt O., Pain L., Lazarus C., Cassell J.C. Combined lesions of cholinergic and serotonergic neurons in the rat brain using 192 IgG-saporin and 5,7-dihydroxytryptamine: neurochemical and behavioral characterization. Eur. J. Neurosci. 12:2000;67-79.
27. Levy M.L., Cummings J.L., Kahn-Rose R. Neuropsychiatric symptoms and cholinergic therapy for Alzheimer's disease. Gerontology. 45:1999;15-22.
28. McDonald M.P., Gleason T.C., Robinson J.K., Crawley J.N. Galanin inhibits performance on rodent memory tasks. Ann. NY Acad. Sci. 863:1998;305-322.
29. Mckenna J.T., P Vertes R. Collateral projections from the median raphe nucleus to the medial septum and hippocampus. Brain Res. Bull. 54:2001;619-630.
30. Menard J., Treit D. Does tolerance develop to the anxiolytic effects of septal lesions? Physiol. Behav. 59:1996;311-318.
31. Menard J., Treit D. Intra-septal infusions of excitatory amino acid receptor antagonists have differential effects in two animal models of anxiety. Behav. Pharmacol. 11:2000;99-108.
32. Ouagazzal A.M., Kenny P.J., File S.E. Modulation of behavior on trials 1 and 2 in the elevated plus-maze test of anxiety after systemic and hippocampal administration of nicotine. Psychopharmacology. 144:1999;54-60.
33. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 1986;Academic Press, New York.
34. Pellow S. Anxiolytic and anxiogenic drug effects in a novel test of anxiety: are exploratory models of anxiety in rodents valid? Methods Find. Exp. Clin. Pharmacol. 8:1986;557-565.
35. Pellow S., Chopin P., File S.E., Briley M. Validation of open:closed arm entries in an elevated plus maze as a measure of anxiety in the rat. J. Neurosci. Methods. 14:1985;149-167.
36. Pellow S., File S.E. Anxiolytic and anxiogenic drug effects on exploratory activity in the elevated plus maze: A novel test of anxiety in the rat. Pharmacol. Biochem. Behav. 24:1986;525-529.
37. Pesold C., Treit D. Excitotoxic lesions of the septum produce anxiolytic effects in the elevated plus-maze and shock-probe burying tests. Physiol. Behav. 52:1992;37-47.
38. Pesold C., Treit D. The septum and the amygdala differentially mediate the anxiolytic effects of benzodiazepines. Brain Res. 638:1994;295-301.
39. Pesold C., Treit D. The central and basolateral amygdala differentially mediate the anxiolytic effects of benzodiazepines. Brain Res. 671:1995;213-221.
40. Pesold C., Treit D. The neuroanatomical specificity of the anxiolytic effects of intra-septal infusions of midazolam. Brain Res. 710:1996;161-168.
41. Pikkarainen M., Ronkko S., Savander V., Insausti R., Pitkanen A. Projections from the lateral, basal, and accessory basal nuclei of the amygdala to the hippocampal formation in rat. J. Comp. Neurol. 403:1999;229-260.
42. Pinel J.P.J., Treit D. Burying as a defensive response in rats. J. Comp. Physiol. Psychol. 92:1978;708-712.
43. Pomerleau O.F., Turk D.C., Fertig J.B. The effects of cigarette smoking on pain and anxiety. Addict. Behav. 9:1984;265-271.
44. Rodgers R.J., Cole J. Effects of scopolamine and its quaternary analogue in the murine elevated plus-maze test of anxiety. Behav. Pharmacol. 6:1995;283-289.
45. Rodgers R.J., Johnson N.J. Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety. Pharmacol. Biochem. Behav. 52:1995;297-303.
46. Sienkiewicz-Jarosz H., Czlonkowska A.I., Siemiatkowski M., Maciejak P., Szyndler J., Plaznik A. The effects of physostigmine and cholinergic receptor ligands on novelty induced neophobia. J. Neural. Transm. 107:2000;1403-1410.
47. Smythe J.W., Murphy D., Bhatnagar S., Timothy C., Costall B. Muscarinic antagonists are anxiogenic in rats tested in the black-white box. Pharmacol. Biochem. Behav. 54:1996;57-63.
48. Smythe J.W., Murphy D., Bhatnagar S., Timothy C., Costall B. The effects of intrahippocampal scopolamine infusions on anxiety in rats as measured by the black-white box test. Brain Res. Bull. 45:1998;89-93.
49. Stancampiano R., Cocco S., Cugusi C., Sarais L., Fadda F. Serotonin and acetylcholine release response in the rat hippocampus during a spatial memory task. Neuroscience. 89:1999;1135-1143.
50. Szyndler J., Sienkiewicz-Jarosz H., Maciejal P., Siemiatkowski M., Rokicki D., Czlonkowska A.I., Plaznik A. The anxiolytic-like effect of nicotine undergoes rapid tolerance in a model of contextual fear conditioning in rats. Pharmacol. Biochem. Behav. 69:2001;511-518.
51. Tateishi N., Takano Y., Honda K., Yamada K., Kamiya Y., Kamiya H. Effects of intrahippocampal injections of the cholinergic neurotoxin AF64A on presynaptic cholinergic markers and on passive avoidance response in the rat. Clin. Exp. Pharmacol. Physiol. 14:1987;611-618.
52. Treit D., Pesold C. Septal lesions inhibit fear reactions in two animal models of anxiolytic drug action. Physiol. Behav. 47:1990;365-371.
53. Treit D. The inhibitory effects of diazepam on defensive burying: anxiolytic vs. analgesic effects. Pharmacol. Biochem. Behav. 22:1985;47-52.
54. Treit D. A comparison of anxiolytic and nonanxiolytic agents in the shock-probe burying test for anxiolytics. Pharmacol. Biochem. Behav. 36:1990;203-205.
55. Treit D., Pinel J.P.J., Fibiger H.C. Conditioned defensive burying: a new paradigm for the study of anxiolytic agents. Pharmacol. Biochem. Behav. 15:1981;619-626.
56. Treit D., Pesold C., Rotzinger S. Dissociating the anti-fear effects of septal and amygdaloid lesions using two pharmacologically validated models of rat anxiety. Behav. Neurosci. 107:1993;770-785.
57. Treit D., Menard J., Pesold C. The shock probe burying test. Neurosci. Protoc. Module. 3:1994;9-17.
58. Treit D., Menard J. Dissociations among the anxiolytic effects of septal, hippocampal, and amygdaloid lesions. Behav. Neurosci. 111:1997;653-658.
59. Tsuda A., Yoshishige I., Tanaka M. The contrasting effects of diazepam and yohimbine on conditioned defensive burying in rats. Psychobiology. 16:1988;213-217.
60. Van Groen T., Wyss J.M. Extrinsic projections from area CA1 of the rat hippocampus: olfactory, cortical, subcortical, and bilateral hippocampal formation projections. J. Comp. Neurol. 302:1990;515-528.
61. Vertes R.P., Fortin W.J., Crane A.M. Projections of the median raphe nucleus in the rat. J. Comp. Neurol. 407:1999;555-582.
62. Walass I., Fonnum F. Biochemical evidence for glutamate as a transmitter in hippocampal efferents to the basal forebrain and hypothalamus in the rat brain. Neuroscience. 5:1980;1691-1698.
63. Weiner M.F., Svetlik D., Risser R.C. What depressive symptoms are reported in Alzheimer's patients? Int. J. Geriatr. Psychiatry. 12:1997;648-652.