Suppression of bone resorption by madindoline a, a novel nonpeptide antagonist to gp130

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 23, 2002, Pages 14728-14733

  Hayashi, Masahiko ^a,c   Rho, Mun Chual ^b,c   Enomoto, Akiko ^c   Fukami, Akiko ^a,c   Kim, Yong Pil ^c   Kikuchi, Yuji ^a,c   Sunazuka, Toshiaki ^a   Hirose, Tomoyasu ^a   Komiyama, Kanki ^c   Omura, Satoshi ^a,c  

^a KITASATO UNIVERSITY   (Japan)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c KITASATO INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 11; INTERLEUKIN 6; JANUS KINASE; MADINDOLINE A; MADINDOLINE B; PROTEIN INHIBITOR; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DIMERIZATION; DOSE RESPONSE; DRUG PROTEIN BINDING; DRUG STRUCTURE; FEMALE; MALE; MOUSE; MULTIPLE MYELOMA; NONHUMAN; OSTEOLYSIS; PATHOGENESIS; POSTMENOPAUSE OSTEOPOROSIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR GROWTH;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BONE RESORPTION; CELL LINE; CYTOKINES; DNA-BINDING PROTEINS; FEMALE; GROWTH INHIBITORS; HUMANS; INDOLES; INTERLEUKIN-2; INTERLEUKIN-3; INTERLEUKIN-4; INTERLEUKIN-6; INTERLEUKIN-8; LEUKEMIA INHIBITORY FACTOR; LYMPHOKINES; MACROPHAGES; MICE; MICE, INBRED C3H; MICE, INBRED STRAINS; NERVE GROWTH FACTOR; RECEPTORS, CYTOKINE; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STEREOISOMERISM; TRANS-ACTIVATORS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; JANUS;

EID: 0037069343     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.232562799     Document Type: Article

References (38)

1. Kishimoto, T., Akira, S. & Taga, T. (1992) Science 258, 593-597.
2. Strassmann, G., Masui, Y., Chizzonite, R. & Fong, M. (1993) J. Immunol. 150, 2341-2345.
3. Yoshizaki, K., Matsuda, T., Nishimoto, N., Kuritani, T., Taeho, L., Aozasa, K., Nakahata, T., Kawai, H., Tagoh, H., Komori, T., et al. (1989) Blood 74, 1360-1367.
4. Takagi, N., Mihara, M., Moriya, Y., Nishimoto, N., Yoshizaki, K., Kishimoto, T., Takeda, Y. & Ohsugi, Y. (1998) Arthritis Rheum. 41, 2117-2121.
5. de la Mata, J., Uy, H. L., Guise, T. A., Story, B., Boyce, B. F., Mundy, G. R. & Roodman, G. D. (1995) J. Clin. Invest. 95, 2846-2852.
6. Zhang, X. G., Bataille, R., Jourdan, M., Saeland, S., Banchereau, J., Mannoni, P. & Klein, B. (1990) Blood 76, 2599-2605.
7. Lutticken, C., Wegenka, U. M., Yuan, J., Buschmann, J., Schindler, C., Ziemiecki, A., Harpur, A. G., Wilks, A. F., Yasukawa, K., Taga, T., et al. (1994) Science 263, 89-92.
8. Hayashi, M., Kim, Y. P., Hiraoka, H., Natori, M., Takamatsu, S., Kawakubo, T., Masuma, R., Komiyama, K. & Omura, S. (1995) J. Antibiot. (Tokyo) 48, 1435-1439.
9. Fukami, A., Iijima, K., Hayashi, M., Komiyama, K. & Omura, S. (2002) Biochem. Biophys. Res. Commun. 291, 1065-1070.
10. Hayashi, M., Kim, Y. P., Takamatsu, S., Enomoto, A., Shinose, M., Takahashi, Y., Tanaka, H., Komiyama, K. & Omura, S. (1996) J. Antibiot. (Tokyo) 49, 1091-1095
11. Sunazuka, T., Hirose, T., Shirahata, T., Harigaya, Y., Hayashi, M., Komiyama, K., Omura, S. & Smith, I. A. B. (2000) J. Am. Chem. Soc. 122, 2122-2123.
12. Carmichael, J., Degraff, W. G., Gazdar, A. F., Minna, J. D. & Mitchell, J. B. (1987) Cancer Res. 47, 936-942.
13. Atkins, G. J., Haynes, D. R., Geary, S. M., Loric, M., Crotti, T. N. & Findlay, D. M. (2000) Bone 26, 653-661.
14. Meydan, N., Grunberger, T., Dadi, H., Shahar, M., Arpaia, E., Lapidot, Z., Leeder, J. S., Freedman, M., Cohen, A., Gazit, A., et al. (1996) Nature 379, 645-648.
15. Savino, R., Ciapponi, L., Lahm, A., Demartis, A., Cabibbo, A., Toniatti, C., Delmastro, P., Altamura, S. & Ciliberto, G. (1994) EMBO J. 13, 5863-5870.
16. Sporeno, E., Savino, R., Ciapponi, L., Paonessa, G., Cabibbo, A., Lahm, A., Pulkki, K., Sun, R. X., Toniatti, C., Klein, B., et al. (1996) Blood 87, 4510-4519.
17. Ward, L. D., Hammacher, A., Howlett, G. J., Matthews, J. M., Fabri, L., Moritz, R. L., Nice, E. C., Weinstock, J. & Simpson, R. J. (1996) J Biol. Chem. 271, 20138-20144.
18. Sato, K., Ohtomo, T., Hirata, Y., Saito, H., Matsuura, T., Akimoto, T., Akamatsu, K., Koishihara, Y., Ohsugi, Y. & Tsuchiya, M. (1996) Hum. Antibodies Hybridomas 7, 175-183.
19. Sato, K., Tsuchiya, M., Saldanha, J., Koishihara, Y., Ohsugi, Y., Kishimoto, T. & Bendig, M. M. (1994) Mol. Immunol. 31, 371-381.
20. Murakami, M., Hibi, M., Nakagawa N., Nakagawa, T., Yasukawa, K., Yamanishi, K., Taga, T. & Kishimoto, T. (1993) Science 260, 1808-1810.
21. Yin, T., Taga, T., Tsang, M. L., Yasukawa, K., Kishimoto, T. & Yang, Y. C. (1993) J. Immunol. 151, 2555-2561.
22. Gearing, D. P., Comeau, M. R., Friend, D. J., Gimpel, S., D., Thut, C. J., McGourty, J., Brasher, K. K., King, J. A., Gillis, S., Mosley, B., et al. (1992) Science 255, 1434-1437.
23. Pennica, D., King, K. L., Shaw, K. J., Luis, E., Rullamas, J., Luoh, S. M., Darbonne, W. C., Knutzon, D. S., Yen, R., Chien, K. R., et al. (1995) Proc. Natl. Acad. Sci. USA 92, 1142-1146.
24. Davis, S., Aldrich, T. H., Stahl, N., Pan, L., Taga, T., Kishimoto, T., Ip, N. Y. & Yancopoulos, G. D. (1993) Science 260, 1805-1808.
25. Gearing, D. P., Thut, C. J., VandeBos, T., Gimpel, S. D., Delaney, P. B., King, J., Price, V., Cosman, D. & Beckmann, M. P. (1991) EMBO J. 10, 2839-2848.
26. Ciapponi, L., Graziani, R., Paonessa, G., Lahm, A., Ciliberto, G. & Savino, R. (1995) J. Biol. Chem. 270, 31249-31254.
27. Paonessa, G., Graziani, R., De Serio, A., Savino, R., Ciapponi, L., Lahm, A., Salvati, A. L., Toniatti, C. & Ciliberto, G. (1995) EMBO J. 14, 1942-1951.
28. Barton, V. A., Hall, M. A., Hudson, K. R. & Heath, J. K. (2000) J. Biol. Chem. 275, 36197-36203.
29. Barton, V. A., Hudson, K. R. & Heath, J. K. (1999) J. Biol. Chem. 274, 5755-5761.
30. Kurth, I., Horsten, U., Pflanz, S., Dahmen, H., Kuster, A., Grotzinger, J., Heinrich, P. C. & Muller-Newen, G. (1999) J. Immunol. 162, 1480-1487.
31. Yawata, H., Yasukawa, K., Natsuka, S., Murakami, M., Yamasaki, K., Hibi, M., Taga, T. & Kishimoto, T. (1993) EMBO J. 12, 1705-1712.
32. Papadopoulos, N. G., Georganas, K., Skoutellas, V., Konstantellos, E. & Lyritis, G. P. (1997) Clin. Rheumatol. 16, 162-165.
33. Lin, S. C., Yamate, T., Taguchi, Y., Borba, V. Z., Girasole, G., O'Brien, C. A., Bellido, T., Abe, E. & Manolagas, S. C. (1997) J. Clin. Invest. 100, 1980-1990.
34. Christiansen, C., Christensen, M. S. & Transbol, I. 1. (1981) Lancet 1, 459-461.
35. Hoszowski, K. (1995) Pol. Tyg. Lek. 50, 41-42.
36. Burckhardt, P. (1999) Schweiz. Med. Wochenschr. 129, 1926-1930.
37. Yasuda, H., Shima, N., Nakagawa, N., Yamaguchi, K., Kinosaki, M., Mochizuki, S., Tomoyasu, A., Yano, K., Goto, M., Murakami, A., et al. (1998) Proc. Natl. Acad. Sci. USA 95, 3597-3602.
38. Girasole, G., Jilka, R. L., Passeri, G., Boswell, S., Boder, G., Williams, D. C. & Manolagas, S. C. (1992) J. Clin. Invest. 89, 883-891.