Antisense inhibition of myoD expression in regenerating rat soleus muscle is followed by an increase in the mRNA levels of myoD, myf-5 and myogenin and by a retarded regeneration

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1590, Issue 1-3, 2002, Pages 52-63

  Zádor, Erno ^a,c   Bottka, Sándor ^b   Wuytack, Frank ^c  

^a UNIVERSITY OF SZEGED   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Antisense oligonucleotide; Muscle regeneration; myoD

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DESMIN; MESSENGER RNA; MUSCLE PROTEIN; MYOD PROTEIN; MYOGENIC FACTOR 5; MYOGENIN; OLIGOMER; ORGANOPHOSPHATE; PHOSPHOROTHIOIC ACID; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MALE; MUSCLE REGENERATION; MYOTUBE; NERVE ENDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOLEUS MUSCLE; TRANSLATION INITIATION;

ANIMALS; BASE SEQUENCE; BROMODEOXYURIDINE; DESMIN; DNA-BINDING PROTEINS; GENE EXPRESSION; INHIBITOR OF DIFFERENTIATION PROTEIN 1; INHIBITOR OF DIFFERENTIATION PROTEIN 2; MALE; MUSCLE PROTEINS; MUSCLE, SKELETAL; MYOD PROTEIN; MYOGENIC REGULATORY FACTOR 5; MYOGENIN; MYOSIN HEAVY CHAINS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; RATS; RATS, WISTAR; REGENERATION; REPRESSOR PROTEINS; RNA, MESSENGER; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 0037067135     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4889(02)00198-2     Document Type: Article

References (44)

1. Molecular mechanisms regulating myogenic determination and differentiation
2. Inactivation of myoD in mice leads to up-regulation of the myogenic HLH gene myf-5 and results in apparently normal muscle development
3. MyoD is required for myogenic stem cell function in adult muscle
4. Reduced differentiation potential of primary myoD-/- myogenic cells derived from adult skeletal muscle
5. The transition from proliferation to differentiation is delayed in satellite cells from mice lacking myoD
6. MyoD-/- satellite cells in single-fiber culture are differentiation defective and MRF4 deficient
7. Myotube formation is delayed but not prevented in myoD-deficient skeletal muscle: Studies in regenerating whole muscle grafts of adult mice
8. Antisense oligonucleotides: New tools for physiology
9. Highly specific inhibition of IGF-I-stimulated differentiation by an antisense oligodeoxyribonucleotide to myogenin mRNA
10. Uncoordinated inhibition of gene expression for muscle proteins by a troponin T antisense oligodeoxynucleotide
11. Pathological responses of rat skeletal muscle for a single subcutaneous injection of a toxin isolated from the venom of the Australian tiger snake, Notechis scutatus scutatus
12. 2+ ATPase isoforms in the rat soleus muscle regenerating from notexin-induced necrosis
13. MRNA levels of myogenic regulatory factors in rat slow and fast muscles regenerating from notexin-induced necrosis
14. 2+ transport ATPase protein isoforms during regeneration from notexin-induced necrosis of rat soleus muscle
15. Regenerating soleus and extensor digitorum longus muscles of the rat show elevated levels of TNF-α and its receptors, TNFR-60 and TNFR-80
16. Expression of myosin isoforms during notexin induced regeneration of rat soleus muscles
17. Nerve-dependent recovery of metabolic pathways in regenerating soleus muscles
18. The morphology of regeneration of skeletal muscles in the rat
19. Minimally modified oligonucleotides - Combination of end-capping and pyrimidine-protection
20. Tetranucleotide GGGA motif in primary RNA transcripts. Novel target site for antisense design
21. Algorithms and thermodynamics for RNA secondary structure prediction. A Practical Guide in RNA Biochemistry and Biotechnology
22. Dibenzoyl tetrasulfide - A rapid sulfur transfer agent in the synthesis of phosphorothioate analogues of oligonucleotides
23. Use of antisense oligonucleotides to verify the role of the α(1A)-adrenergic receptor in the contractility of the rat uterus post partum
24. The 2′-5′ oligoadenylate/RNase L/RNase L inhibitor pathway regulates both myoD mRNA stability and muscle cell differentiation
25. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
26. Isolation and structural analysis of the rat myoD gene
27. Transcriptional regulation in cardiac muscle: Coordiante expression of Id with a neonatal phenotype during development and following a hypertrophic stimulus in adult rat ventricular myocytes in vitro
28. Activation of helix-loop-helix proteins Id1, Id2 and Id3 during neural differentiation
29. Prolonged passive stretch of rat soleus muscle provokes an increase in the mRNA levels of the muscle regulatory factors distributed along the entire length of the fibers
30. 2+ pump is expressed in platelets, in lymphoid cells and in mast cells
31. Muscle differentiation is inhibited by the helix-loop-helix protein Id3
32. Differential interactions of Id proteins with basic-helix-loop-helix transcriptional factors
33. Neuromuscular transmission at newly formed neuromuscular junctions in the regenerating soleus muscle of the rat
34. Autonomous differentiation in the mouse myogenic cell line, C2, involves a mutual positive control between insulin-like growth factor II and myoD, operating as early as at the myoblast stage
35. Expression of CD34 and myf-5 defines the majority of quiescent adult skeletal muscle satellite cells
36. Degradation of myogenic transcription factor myoD by the ubiquitin pathway in vivo and in vitro: Regulation by specific DNA binding
37. The expression of the myogenic regulatory factors in denervated and normal muscles of different phenotypes
38. The adaptive response of myoD family proteins in overloaded, regenerating and denervated rat soleus muscles
39. The molecular regulation of myogenesis
40. Single-cell analysis of regulatory gene expression in quiescent and activated mouse skeletal muscle cells
41. Chemotaxis of skeletal muscle satellite cells
42. A new look at the origin, function, and "stem-cell" status of muscle satellite cells
43. The fate of desmin and titin during the degeneration and regeneration of the soleus muscles of the rat