Enantio-dependent binding and transactivation of optically active phenylpropanoic acid derivatives at human peroxisome proliferator-activated receptor alpha

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 3, 2002, Pages 333-335

  Miyachi, Hiroyuki ^a   Nomura, Masahiro ^a   Tanase, Takahiro ^a   Suzuki, Masahiro ^a   Murakami, Koji ^a   Awano, Katsuya ^a  

^a KYORIN PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROPIONIC ACID DERIVATIVE;

ARTICLE; BINDING ASSAY; CHEMICAL REACTION; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; ENANTIOMER; ISOMER; OPTICAL ROTATION; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; TRANSACTIVATION;

CRYSTALLOGRAPHY, X-RAY; HUMANS; MOLECULAR CONFORMATION; PHENYLPROPIONATES; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

EID: 0037059928     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00732-6     Document Type: Article

References (24)