The role of transhepatic bile salt flux in the control of hepatic secretion of triacylglycerol-rich lipoproteins in vivo in rodents

Biochimica et Biophysica Acta - General Subjects

Volumn 1573, Issue 1, 2002, Pages 9-20

  Elzinga, Baukje M ^a   Havinga, Rick ^a   Baller, Julius F W ^a   Wolters, Henk ^a   Bloks, Vincent ^a   Mensenkamp, Arjen R ^a   Kuipers, Folkert ^a   Verkade, Henkjan J ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Cholestyramine; Lipid; Liver; Taurocholate; Very low density lipoprotein

Indexed keywords

BILE SALT; COLESTYRAMINE; TAUROCHOLIC ACID; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BILE FLOW; CONTROLLED STUDY; DIET SUPPLEMENTATION; LIPID COMPOSITION; LIVER FUNCTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; APOLIPOPROTEINS B; BILE ACIDS AND SALTS; BILE DUCTS, INTRAHEPATIC; CARRIER PROTEINS; CHOLESTYRAMINE; DIET; LIPOPROTEINS, VLDL; LIVER; MICE; MICE, INBRED C57BL; RATS; RATS, WISTAR; TAUROCHOLIC ACID; TRIGLYCERIDES;

RODENTIA;

EID: 0037057864     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4165(02)00275-1     Document Type: Article

References (46)

1. Shelness G.S., Sellers J.A. Very-low-density lipoprotein assembly and secretion. Curr. Opin. Lipidol. 12:2001;151-157.
2. Verkade H.J., Vonk R.J., Kuipers F. New insights into the mechanism of bile acid-induced biliary lipid secretion. Hepatology. 21:1995;1174-1189.
3. Lin Y., Havinga R., Verkade H.J., Moshage H., Slooff M.J., Vonk R.J., Kuipers F. Bile acids suppress the secretion of very-low-density lipoprotein by human hepatocytes in primary culture. Hepatology. 23:1996;218-228.
4. Lin Y., Havinga R., Schippers I.J., Verkade H.J., Vonk R.J., Kuipers F. Characterization of the inhibitory effects of bile acids on very-low-density lipoprotein secretion by rat hepatocytes in primary culture. Biochem. J. 316:1996;531-538.
5. Duane W.C. Abnormal bile acid absorption in familial hypertriglyceridemia. J. Lipid Res. 36:1995;96-107.
6. Angelin B., Hershon K.S., Brunzell J.D. Bile acid metabolism in hereditary forms of hypertriglyceridemia: evidence for an increased synthesis rate in monogenic familial hypertriglyceridemia. Proc. Natl. Acad. Sci. U. S. A. 84:1987;5434-5438.
7. Nestel P.J., Grundy S.M. Changes in plasma triglyceride metabolism during withdrawal of bile. Metabolism. 25:1976;1259-1268.
8. Grundy S.M., Ahrens E.H. Jr., Salen G. Interruption of the enterohepatic circulation of bile acids in man: comparative effects of cholestyramine and ileal exclusion on cholesterol metabolism. J. Lab. Clin. Med. 78:1971;94-121.
9. Miller N.E., Clifton-Bligh P., Nestel P.J. Effects of colestipol, a new bile-acid-sequestering resin on cholesterol metabolism in man. J. Lab. Clin. Med. 82:1973;876-890.
10. Miller N.E., Nestel P.J. Triglyceride-lowering effect of chenodeoxycholic acid in patients with endogenous hypertriglyceridaemia. Lancet. 2:1974;929-931.
11. Makishima M., Okamoto A.Y., Repa J.J., Tu H., Learned R.M., Luk A., Hull M.V., Lustig K.D., Mangelsdorf D.J., Shan B. Identification of a nuclear receptor for bile acids. Science. 284:1999;1362-1365.
12. Lu T.T., Makishima M., Repa J.J., Schoonjans K., Kerr T.A., Auwerx J., Mangelsdorf D.J. Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. Mol. Cell. 6:2000;507-515.
13. Chiang J.Y.L., Kimmel R., Weinberger C., Stroup D. Farnesoid X Receptor responds to bile acids and represses cholesterol 7α-hydroxylase Gene (CYP7A1) transcription. J. Biol. Chem. 275:2000;10918-10924.
14. Peet D.J., Turley S.D., Ma W., Janowski B.A., Lobaccaro J.M., Hammer R.E., Mangelsdorf D.J. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell. 93:1998;693-704.
15. Shimano H., Horton J.D., Hammer R.E., Shimomura I., Brown M.S., Goldstein J.L. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J. Clin. Invest. 98:1996;1575-1584.
16. Horton J.D., Shimomura I., Brown M.S., Hammer R.E., Goldstein J.L., Shimano H. Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2. J. Clin. Invest. 101:1998;2331-2339.
17. Miyake J.M., Doung X.-D.T., Strauss W., Moore G.L., Castellani L.W., Curtiss L.K., Taylor J.M., Davis R.A. Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7α-hydroxylase. J. Biol. Chem. 276:2001;23304-23311.
18. Kuipers F., Havinga R., Bosschieter H., Toorop G.P., Hindriks F.R., Vonk R.J. Enterohepatic circulation in the rat. Gastroenterology. 88:1985;403-411.
19. Li X., Catalina F., Grundy S.M., Patel S. Method to measure apolipoprotein B48 and B100 secretion rates in an individual mouse: evidence for a very rapid turnover of VLDL and preferential removal of B48-Relative to B100-containing lipoproteins. J. Lipid Res. 37:1996;210-220.
20. Kuipers F., Lin Y., Havinga R., Bloks V., Verkade H.J., Jong M.C., Hofker M.H., Moshage H., Van Vlijmen B.J.M., Vonk R.J., Havekes L.M. Impaired secretion of very-low-density lipoprotein triglycerides by apolipoprotein E-deficient mouse hepatocytes. J. Clin. Invest. 100:1997;2915-2922.
21. Klaunig J.E., Goldblatt P.J., Hinton D.E., Lipsky M.M., Chacko J., Trump B.F. Mouse liver cell culture: I. Hepatocyte isolation. In Vitro. 17:1981;913-925.
22. Bligh E.G., Dyer W.J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37:1959;911-917.
23. Vance D.E., Weinstein D.B., Steinberg D. Isolation and analysis of lipoproteins secreted by rat liver hepatocytes. Biochim. Biophys. Acta. 792:1984;39-47.
24. Wetterau J.R., Aggerbeck L.P., Bouma M.E., Eisenberg C., Munck A., Hermier M., Schmitz J., Gay G., Rader D.J., Gregg R.E. Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia. Science. 258:1992;999-1001.
25. Ritchie P.J., Decout A., Amy J., Mann C.J., Read J., Rosseneu M., Scott J., Shoulders C.C. Baculovirus expression and biochemical characterization of the human microsomal triglyceride transfer protein. Biochem. J. 338:1999;305-310.
26. Lowry O.H., Rosenbrough N.J., Farr A.L., Randall R.J. Protein measurement with folin reagent. J. Biol. Chem. 193:1951;265-275.
27. Murphy G.M., Billing B.H., Baron D.N. A fluorimetric and enzymatic method for the estimation of serum total bile acids. J. Clin. Pathol. 23:1970;594-598.
28. Verkade H.J., Havinga R., Gerding A., Vonk R.J., Kuipers F. Mechanism of bile acid-induced biliary lipid secretion in the rat: effect of conjugated bilirubin. Am. J. Physiol. 264:1993;G462-G469.
29. Smit M.J., Temmerman A.M., Havinga R., Kuipers F., Vonk R.J. Short- and long-term effects of biliary drainage on hepatic cholesterol metabolism in the rat. Biochem. J. 269:1990;781-788.
30. Komai K., Sabesin S.M., Weidman S.W. Inhibition of hepatic triglyceride secretion and exogenous triglyceride clearance in the cholestatic rat. Atherosclerosis. 64:1987;147-153.
31. Meijer G.W., Beynen A.C. Lipid and carbohydrate metabolism in cholestyramine-fed rats. Artery. 16:1989;286-292.
32. Imai Y., Kawata S., Inada M., Miyoshi S., Minami Y., Matsuzawa Y., Uchida K., Tarui S. Effect of cholestyramine on bile acid metabolism in conventional rats. Lipids. 22:1987;513-516.
33. Younes H., Levrat M.A., Demigne C., Remesy C. Resistant starch is more effective than cholestyramine as a lipid-lowering agent in the rat. Lipids. 30:1995;847-853.
34. Hulzebos C.V., Renfurm L., Bandsma R.H., Verkade H.J., Boer T., Boverhof R., Tanaka H., Mierau I., Sauer P.J.J., Kuipers F., Stellaard F. Measurements of parameters of cholic acid kinetics in plasma using a micro scale stable isotope dilution technique: application to rodents and man. J. Lipid Res. 42:2001;1923-1929.
35. Repa J.J., Lund E.G., Horton J.D., Leitersdorf E., Russell D.W., Dietschy J.M., Turley S.D. Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding. J. Biol. Chem. 275:2000;39685-39692.
36. Pullinger C.R., North J.D., Teng B.B., Rifici V.A., Ronhild de Brito A.E., Scott J. The apolipoprotein B gene is constitutively expressed in HepG2 cells: regulation of secretion by oleic acid, albumin, and insulin, and measurement of the mRNA half-life. J. Lipid Res. 30:1989;1065-1077.
37. Gordon D.A., Jamil H. Progress toward understanding the role of microsomal triglyceride transfer protein in apolipoprotein-B lipoprotein assembly. Biochim. Biophys. Acta. 1486:2000;72-83.
38. Brown A., Wiggins D., Gibbons G.F. Manipulation of cholesterol and cholesteryl ester synthesis has multiple effects on the metabolism of apolipoprotein B and the secretion of very-low-density lipoprotein by primary hepatocyte cultures. Biochim. Biophys. Acta. 1440:1999;253-265.
39. Tanaka M., Jingami H., Otani H., Cho M., Ueda Y., Arai H., Nagano Y., Doi T., Yokode M., Kita T. Regulation of apolipoprotein B production and secretion in response to the change of intracellular cholesteryl ester contents in rabbit hepatocytes. J. Biol. Chem. 268:1993;12713-12718.
40. Buhman K.K., Accad M., Novak S., Choi R.S., Wong J.S., Hamilton R.L., Turley S.D., Farese R.V.J. Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice. Nat. Med. 6:2000;1341-1347.
41. Joyce C., Skinner K., Anderson R.A., Rudel L.L. Acyl-coenzyme A: cholesteryl acyltransferase 2. Curr. Opin. Lipidol. 10:1999;89-95.
42. Yao Z.M., Vance D.E. Reduction in VLDL, but not HDL, in plasma of rats deficient in choline. Biochem. Cell Biol. 68:1990;552-558.
43. Reihner E., Angelin B., Rudling M., Ewerth S., Bjorkhem I., Einarsson K. Regulation of hepatic cholesterol metabolism in humans: stimulatory effects of cholestyramine on HMG-CoA reductase activity and low-density lipoprotein receptor expression in gallstone patients. J. Lipid Res. 31:1990;2219-2226.
44. Kang S., Davis R.A. Cholesterol and hepatic lipoprotein assembly and secretion. Biochim. Biophys. Acta. 1529:2000;223-230.
45. Sinal C.J., Tohkin M., Miyata M., Ward J.M., Lambert G., Gonzalez F.J. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell. 102:2000;731-744.
46. Zeniya M., Reuben A. Triton WR-1339-induced changes in serum lipids and biliary lipid secretion. Am. J. Physiol. 254:1988;G346-G354.