Apolipoprotein E genotype does not predict decline in intelligence in healthy older adults

Neuroscience Letters

Volumn 324, Issue 1, 2002, Pages 74-76

  Pendleton, Neil ^a   Payton, Anthony ^b   van den Boogerd, Eelke H ^a   Holland, Fiona ^c   Diggle, Peter ^d   Rabbitt, Patrick M A ^b   Horan, Michael A ^a   Worthington, Jane ^e   Ollier, William E R ^b  

^a Clinical Division i   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d LANCASTER UNIVERSITY   (United Kingdom)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Aged; Apolipoprotein E; Genetics; Intelligence

Indexed keywords

APOLIPOPROTEIN E;

ADULT; AGE; AGED; ARTICLE; COGNITION; CONTROLLED STUDY; CORRELATION FUNCTION; FEMALE; GENOTYPE; HUMAN; HUMAN EXPERIMENT; INTELLIGENCE; INTELLIGENCE TEST; LONGITUDINAL STUDY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; APOLIPOPROTEIN E2; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; BRAIN; BRAIN CHEMISTRY; COGNITION DISORDERS; COHORT STUDIES; DNA MUTATIONAL ANALYSIS; FEMALE; GENE FREQUENCY; GENETIC SCREENING; GENOTYPE; HUMANS; INTELLIGENCE; MALE; MIDDLE AGED; MODELS, STATISTICAL; PREDICTIVE VALUE OF TESTS; SEX FACTORS; STATISTICS;

EID: 0037052759     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)00135-0     Document Type: Article

References (12)

1. Early effect of ApoE-epsilon 4 allele on cognitive results in a group of highly performing subjects: The EVA study. Etude sur le Vieillissement Arteriel
2. Apolipoprotein e4 allele and cognitive decline in elderly men
3. Apolipoprotein E and cognitive change in an elderly population
4. Association between apolipoprotein E epsilon4 and the rate of cognitive decline in community-dwelling elderly individuals with and without dementia
5. Memory performance in healthy elderly without Alzheimer's disease: Effects of time and apolipoprotein-E
6. Identifying and separating the effects of practice and of cognitive ageing during a large longitudinal study of elderly community residents
7. Three-year changes in cognitive performance as a function of apolipoprotein E genotype: Evidence from very old adults without dementia
8. Is APOE-epsilon4 a risk factor for cognitive impairment in normal aging?
9. Apolipoprotein E genotype influences cognitive 'phenotype' in patients with Alzheimer's disease but not in healthy control subjects
10. Apolipoprotein E genotypes and cognitive functions in healthy elderly persons
11. Consensus statement apolipoprotein E genotyping in Alzheimer's disease
12. Apolipoprotein E phenotype and cognitive decline in a prospective study of elderly community women