Kinetic resolution of racemic lactones by conjugate additions of allylic organolithium species: Direct formation of three contiguous centers with high diastereo- and enantioselectivities

Organic Letters

Volumn 4, Issue 16, 2002, Pages 2657-2660

  Lim, Sung H ^a   Beak, Peter ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LACTONE; LITHIUM DERIVATIVE; ORGANOMETALLIC COMPOUND;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; KINETICS; STEREOISOMERISM; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; KINETICS; LACTONES; LITHIUM COMPOUNDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; STEREOISOMERISM;

EID: 0037043494     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0263898     Document Type: Article

References (32)

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26. The selectivity factor, s = ln [1 - C(1 + ee)]/[1 - C(1 - ee)], was calculated using the enantiomeric excess of the conjugate addition product. For each substrate, s was greater than 20.
27. Crystallographic data for structure of 5 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication no. CCDC 18373. Copies of the data can be obtained free of charge upon application to the CCDC, 12 Union Road, Cambridge CB2 1EZ, U.K. (fax (+44) 1223-336033; e-mail deposit@ccdc.cam.ac.uk).
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31. 6,15
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