Discovery of imidazole glycerol phosphate dehydratase inhibitors through 3-D database searching

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 13, 2002, Pages 1743-1746

  Schweitzer, Barbara A ^a   Loida, Paul J ^a   CaJacob, Claire A ^a   Chott, Robert C ^a   Collantes, Elizabeth M ^a   Hegde, Shridhar G ^a   Mosier, Philip D ^a   Profeta, Salvatore ^a  

^a MONSANTO COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; HERBICIDE; ALDEHYDE; HYDROLYASE; IMIDAZOLEGLYCEROLPHOSPHATE DEHYDRATASE; PYRROLE DERIVATIVE; TRIAZOLE DERIVATIVE;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; PHARMACOPHORE; SYNTHESIS; CHEMICAL MODEL; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; FACTUAL DATABASE; IC 50;

ALDEHYDES; BINDING SITES; DATABASES, FACTUAL; ENZYME INHIBITORS; HERBICIDES; HYDRO-LYASES; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; MOLECULAR CONFORMATION; PYRROLES; TRIAZOLES;

MAMMALIA;

EID: 0037042771     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00283-4     Document Type: Article

References (23)