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Volumn 288, Issue 1-2, 2002, Pages 13-21
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Incorporating human interindividual biotransformation variance in health risk assessment
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Author keywords
Concentration; Extrapolation; Metabolism; Pharmacokinetics
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Indexed keywords
BIOLOGICAL ORGANS;
CHEMICALS;
ENZYMES;
EXTRAPOLATION;
METABOLISM;
PHARMACOKINETICS;
PHYSIOLOGICAL MODELS;
RISK ASSESSMENT;
BIOTRANSFORMATION;
HEALTH RISKS;
CYTOCHROME P450;
PROTEIN;
HEALTH RISK;
RISK ASSESSMENT;
ANALYSIS OF VARIANCE;
ANATOMY;
ARTICLE;
BIOCHEMISTRY;
BIOLOGICAL MODEL;
BIOTRANSFORMATION;
CHEMICAL REACTION;
CHEMICAL REACTION KINETICS;
CONCENTRATION (PARAMETERS);
CONTROLLED STUDY;
DETOXIFICATION;
ENDOPLASMIC RETICULUM;
ENVIRONMENTAL FACTOR;
ENZYME ANALYSIS;
ENZYME LOCALIZATION;
EXPOSURE;
HEALTH HAZARD;
HEREDITY;
HUMAN;
IN VITRO STUDY;
ISOLATION PROCEDURE;
LIFESTYLE;
LIVER;
LIVER METABOLISM;
METABOLIC RATE;
MICHAELIS CONSTANT;
MICROSOME;
PHYSIOLOGY;
PREDICTION;
PRIORITY JOURNAL;
PROTECTION;
PROTEIN EXPRESSION;
RISK;
RISK ASSESSMENT;
SAMPLING;
TISSUE HOMOGENATE;
XENOBIOTIC METABOLISM;
BIOTRANSFORMATION;
CELL CULTURE TECHNIQUES;
CYTOCHROME P-450 ENZYME SYSTEM;
ENZYME INDUCTION;
HUMANS;
LIVER;
MICROSOMES, LIVER;
PUBLIC HEALTH;
REPRODUCIBILITY OF RESULTS;
RESEARCH DESIGN;
RISK ASSESSMENT;
XENOBIOTICS;
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EID: 0037041195
PISSN: 00489697
EISSN: None
Source Type: Journal
DOI: 10.1016/S0048-9697(01)01115-9 Document Type: Article |
Times cited : (26)
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References (8)
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