Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 7, 2002, Pages 1109-1112

  Wouters, Johan ^a   Huygens, Marjorie ^a   Pochet, Lionel ^a   Pirotte, Bernard ^b   Durant, François ^a   Masereel, Bernard ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMOTRYPSIN A; COUMARIN DERIVATIVE;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG MECHANISM; DRUG POTENCY; ELECTRIC POTENTIAL; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME INHIBITION; PHARMACOPHORE; X RAY CRYSTALLOGRAPHY;

ANTICOAGULANTS; BINDING SITES; CHYMOTRYPSIN; COUMARINS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MODELS, STRUCTURAL;

EID: 0037041189     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00073-2     Document Type: Article

References (10)