Immunogenicity and protective efficacy of three DNA vaccines encoding pre-erythrocytic- and erythrocytic-stage antigens of Plasmodium cynomolgi in rhesus monkeys

FEMS Immunology and Medical Microbiology

Volumn 34, Issue 1, 2002, Pages 33-43

  Bhardwaj, Devesh ^a   Hora, Bhavna ^a   Singh, Naresh ^a   Puri, Sunil Kumar ^b   Lalitha, Punchayil ^a   Rupa, Prithy ^a   Chauhan, Virander Singh ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

DNA vaccine; Malaria; Plasmodium cynomolgi; Sporozoite

Indexed keywords

APICAL MEMBRANE ANTIGEN 1; DNA VACCINE; MEROZOITE SURFACE PROTEIN 1; THROMBOSPONDIN RELATED ADHESIVE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG TARGETING; FEMALE; GENETIC CODE; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; MALE; MONKEY; MONONUCLEAR CELL; MOUSE; NONHUMAN; PARASITEMIA; PARASITOSIS; PLASMID; PLASMODIUM CYNOMOLGI; PRIORITY JOURNAL; PROTOZOAL INFECTION; RHESUS MONKEY; SPOROZOITE;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; BASE SEQUENCE; DNA, PROTOZOAN; ERYTHROCYTES; FEMALE; IMMUNITY, CELLULAR; IMMUNIZATION; MACACA MULATTA; MALARIA; MALARIA VACCINES; MALE; MICE; MICE, INBRED BALB C; PARASITEMIA; PLASMIDS; PLASMODIUM CYNOMOLGI; VACCINES, DNA;

EID: 0037031591     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-8244(02)00341-3     Document Type: Article

References (34)

1. Clyde D.F. Immunity to falciparum and vivax malaria induced by irradiated sporozoites: a review of the University of Maryland studies, 1971-1975. Bull. WHO. 68:(suppl.):1990;9-12.
2. Rickman K.H. Human immunization with attenuated sporozoites. Bull. WHO. 68:(Suppl.):1990;13-16.
3. Anders R.F., Crewther P.E., Edwards S., Margetts M., Matthew M.L.S.M., Pollock B., Pye D. Immunization with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi. Vaccine. 16:1998;240-247.
4. Perera K.L.R.L., Handunetti S.M., Holm I., Longacre S., Mendis K. Baculovirus merozoite surface protein 1 C-terminal recombinant antigens are highly protective in a natural primate model for human Plasmodium vivax malaria. Infect. Immun. 66:1998;1500-1506.
5. Aidoo M., Lalvani A., Allsopp H.P., Plebanski M., Meisner S.J., Krausa P., Browning M., Morris-Jones S., McAdam S., Gotch F., Fidock D.A., Takiguchi M., Robson K.J.H., Greenwood B.M., Druihle P., Whittle H.C., Hill A.V.S. Identification of conserved antigenic components for a cytotoxic T lymphocyte-inducing vaccine against malaria. Lancet. 345:1995;1003-1009.
6. Robson K.J.H., Frevert U., Reckman I., Cowan G., Beier J., Scragg I.G., Takehara K., Bishop D.H.L., Pradel G., Sinden R., Saccheo S., Muller H.M., Crisanti A. Thrombospondin related adhesive protein (TRAP) of Plasmodium falciparum expression during sporozoite ontogeny and binding to human hepatocytes. EMBO J. 14:1995;3883-3889.
7. Chauhan V.S. Progress towards malaria vaccine. Curr. Sci. 71:1996;967-971.
8. Donnelly J.J., Ulmer J.B., Shiver J.W., Liu M.A. DNA vaccines. Annu. Rev. Immunol. 15:1997;617-648.
9. Gurunathan S., Klinman D.M., Seder R.A. DNA vaccines: immunology, application and optimisation. Annu. Rev. Immunol. 18:2000;927-974.
10. Tang D.C., De Vit M., Johnston S.A. Genetic immunization is a simple method for eliciting an immune response. Nature. 356:1992;152-154.
11. Wolff J.A., Malone R.W., Williams P., Chong W., Acsadi G., Jani A., Felgner P.L. Direct gene transfer into mouse muscle in vivo. Science. 247:1990;1465-1468.
12. Schneider J., Gilbert S.C., Blanchard T.J., Hanke T., Robson K.J., Hannan C.M., Becker M., Sinden R., Smith G.L., Hill A.V. Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara. Nat. Med. 4:1998;397-402.
13. Sedegah M., Hedstrom R., Hobart P., Hoffman S.L. Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein. Proc. Natl. Acad. Sci. USA. 91:1994;9866-9870.
14. Becker S.I., Wang R., Hedstrom R.C., Aguiar J.C., Jones T.R., Hoffman S.L., Gardner M.J. Protection of mice against Plasmodium yoelii sporozoite challenge with P. yoelii merozoite surface protein 1 DNA vaccines. Infect. Immun. 66:1998;3457-3461.
15. Kang Y., Calvo P.A., Daly T.M., Long C.A. Comparison of humoral immune responses elicited by DNA and protein vaccines based on merozoite surface protein-1 from Plasmodium yoelii, a rodent malaria parasite. J. Immunol. 161:1998;4211-4219.
16. Weiss W.R., Ishii K.J., Hedstrom R.C., Sedegah M., Ichino M., Barnhart K., Klinman D.M., Hoffman S.L. A plasmid encoding murine granulocyte-macrophage colony-stimulating factor increases protection conferred by a malaria DNA vaccine. J. Immunol. 161:1998;2325-2332.
17. Sedegah M., Jones T.R., Kaur M., Hedstrom R., Hobart P., Tine J.A., Hoffman S.L. Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine. Proc. Natl. Acad. Sci. USA. 95:1998;7648-7653.
18. Wang R., Doolan D.L., Charoenvit Y., Hedstrom R.C., Gardner M.J., Hobart P., Tine J., Sedegah M., Fallarme V., Sacci J.B.Jr., Kaur M., Klinman D.M., Hoffman S.L., Weiss W.R. Simultaneous induction of multiple antigen-specific cytotoxic T lymphocytes in nonhuman primates by immunization with a mixture of four Plasmodium falciparum DNA plasmids. Infect. Immun. 66:1998;4193-4202.
19. Wang R., Doolan D.L., Le T.P., Hedstrom R.C., Coonan K.M., Charoenvit Y., Jones T.R., Hobart P., Margalith M., Ng J., Weiss W.R., Sedegah M., de Taisne C., Norman J.A., Hoffman S.L. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science. 282:1998;476-480.
20. Mendis K.N. Simian malaria models for research on human disease. Ceylon Med. J. Sci. 38:1995;31-35.
21. Escalante A.A., Ayala F.J. Phylogeny of the malarial genus Plasmodium, derived from rRNA sequences. Proc. Natl. Acad. Sci. USA. 91:1994;11373-11377.
22. Sijwali P.S., Malhotra P., Puri S.K., Chauhan V.S. Cloning and sequence analysis of the thrombospondin-related adhesive protein (TRAP) gene of Plasmodium cynomolgi bastianelli. Mol. Biochem. Parasitol. 90:1997;371-376.
23. Dutta S., Malhotra P., Chauhan V.S. Sequence analysis of apical membrane antigen 1 (AMA-1) of Plasmodium cynomolgi bastianelli. Mol. Biochem. Parasitol. 73:1995;267-270.
24. Longacre S. The Plasmodium cynomolgi merozoite surface protein 1 C-terminal sequence and its homologies with other Plasmodium species. Mol. Biochem. Parasitol. 64:1995;191-205.
25. Luke C.J., Carner K., Liang X., Barbour A.G. An OspA-based DNA vaccine protects mice against infection with Borrelia burgdorferi. J. Infect. Dis. 175:1997;91-97.
26. Sato Y., Roman M., Tighe H., Lee D., Corr M., Nguyen M.D., Silverman G.J., Lotz M., Carson D.A., Raz E. Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science. 273:1996;352-354.
27. Kushwaha A., Rao P.P., Suresh R.P., Chauhan V.S. Immunogenicity of recombinant fragments of Plasmodium falciparum acidic basic repeat antigen produced in E. coli. Parasite Immunol. 23:2001;435-444.
28. Rogers W.O., Baird K.J., Kumar A., Tine J.A., Weiss W., Aguiar J.C., Gowda K., Gwadz R., Kumar S., Gold M., Hoffman S.L. Multistage multiantigen heterologous prime boost vaccine for Plasmodium knowlesi malaria provides partial protection in rhesus macaques. Infect. Immun. 69:2001;5565-5572.
29. Rogers W.O., Gowda K., Hoffman S.L. Construction and immunogenicity of DNA vaccine plasmids encoding four Plasmodium vivax candidate vaccine antigens. Vaccine. 17:1999;3136-3144.
30. Gramzinski R.A., Maris D.C., Doolan D., Charoenvit Y., Obaldia N., Rossan R., Sedegah M., Wang R., Hobart P., Margalith M., Hoffman S.L. Malaria DNA vaccines in Aotus monkeys. Vaccine. 15:1997;913-915.
31. Davis H.L., McCluskie M.J., Gerin J.L., Purcell R.H. DNA vaccine for hepatitis B: evidence for immunogenicity in chimpanzees and comparison with other vaccines. Proc. Natl. Acad. Sci. USA. 93:1996;7213-7218.
32. Prince A.M., Whalen R., Brotman B. Successful nucleic acid based immunization of newborn chimpanzees against hepatitis B virus. Vaccine. 15:1997;916-919.
33. Schmidt L.H., Fradkin R., Genther C.S., Rossan R.N., Squires W. Plasmodium cynomolgi infections in the rhesus monkeys. Am. J. Trop. Med. Hyg. 31:(suppl.):1982;612-645.
34. Puri S.K., Singh N. Azithromycin: antimalarial profile against blood- and sporozoite-induced infections in mice and monkeys. Exp. Parasitol. 94:2000;8-14.