메뉴 건너뛰기




Volumn 73, Issue 10, 1996, Pages 1187-1192

Novel anti-tumour activity of 2,3,5-trimethyl-6-(3-pyridylmethyl)-1,4-benzoquinone (CV-6504) against established murine adenocarcinomas (MAC)

Author keywords

Anti tumour; Lipoxygenase inhibitor; Murine adenocarcinoma; Quinone

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; BENZOQUINONE DERIVATIVE; CYTOTOXIC AGENT; DIHYDROLIPOAMIDE DEHYDROGENASE; HYDROQUINONE; LINOLEIC ACID; LIPOXYGENASE INHIBITOR; SCAVENGER; THROMBOXANE SYNTHASE INHIBITOR;

EID: 0030015089     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.229     Document Type: Article
Times cited : (23)

References (24)
  • 1
  • 2
    • 0026768674 scopus 로고
    • Epidermal growth factor enhances a microsomal 12-lipoxygenase activity in A431 cells
    • CHANG , W-C, NING C-C, LIN MT AND HUANG JD. (1992). Epidermal growth factor enhances a microsomal 12-lipoxygenase activity in A431 cells. J. Biol. Chem., 267, 3657-3666.
    • (1992) J. Biol. Chem. , vol.267 , pp. 3657-3666
    • Chang, W.-C.1    Ning, C.-C.2    Lin, M.T.3    Huang, J.D.4
  • 3
    • 0026437301 scopus 로고
    • Fatty acid modulation of tumor cell - Platelet - vessel wall interaction
    • CHEN Y, LIU B, TANG DG AND HONN KV. (1992). Fatty acid modulation of tumor cell - platelet - vessel wall interaction. Cancer Metastasis Rev., 11, 389-410.
    • (1992) Cancer Metastasis Rev. , vol.11 , pp. 389-410
    • Chen, Y.1    Liu, B.2    Tang, D.G.3    Honn, K.V.4
  • 5
    • 0016611512 scopus 로고
    • Transplantation of adenocarcinoma of the colon in mice
    • DOUBLE JA, BALL CR AND COWEN PN. (1975). Transplantation of adenocarcinoma of the colon in mice. J. Natl Cancer Inst., 54, 271-275.
    • (1975) J. Natl Cancer Inst. , vol.54 , pp. 271-275
    • Double, J.A.1    Ball, C.R.2    Cowen, P.N.3
  • 6
    • 0024346207 scopus 로고
    • Therapeutic index: A vital component in selection of anticancer agents for clinical trial
    • DOUBLE JA AND BIBBY MC. (1989). Therapeutic index: a vital component in selection of anticancer agents for clinical trial. J. Natl Cancer Inst., 81, 988-994.
    • (1989) J. Natl Cancer Inst. , vol.81 , pp. 988-994
    • Double, J.A.1    Bibby, M.C.2
  • 7
    • 0025080893 scopus 로고
    • Epidermal growth factor stimulates linoleic acid metabolism in BALB/c 3T3 fibroblasts
    • GLASGOW WC AND ELING TE. (1990). Epidermal growth factor stimulates linoleic acid metabolism in BALB/c 3T3 fibroblasts. Mol. Pharmacol., 38, 503-510.
    • (1990) Mol. Pharmacol. , vol.38 , pp. 503-510
    • Glasgow, W.C.1    Eling, T.E.2
  • 8
    • 0027215979 scopus 로고
    • Kinetics of the inhibition of tumour growth in mice by eicosapentaenoic acid-reversal by linoleic acid
    • HUDSON EA, BECK SA AND TISDALE MJ. (1993). Kinetics of the inhibition of tumour growth in mice by eicosapentaenoic acid-reversal by linoleic acid. Biochem. Pharmacol., 45, 2189-2194.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 2189-2194
    • Hudson, E.A.1    Beck, S.A.2    Tisdale, M.J.3
  • 9
    • 0028357520 scopus 로고
    • Effect of polyunsaturated fatty acids on the growth of murine colon adenocarcinomas in vitro and in vivo
    • HUSSEY HJ AND TISDALE MJ. (1994). Effect of polyunsaturated fatty acids on the growth of murine colon adenocarcinomas in vitro and in vivo. Br. J. Cancer, 70, 6-10.
    • (1994) Br. J. Cancer , vol.70 , pp. 6-10
    • Hussey, H.J.1    Tisdale, M.J.2
  • 10
    • 0027379882 scopus 로고
    • Anti-angiogenic activity of arachidonic acid metabolism inhibitors in angiogenesis model systems involving human microvascular endothelial cells and neovascularization in mice
    • ITO K, ABE T, TOMITA M, MORIMOTO A, KOHNO K, MORI T, ONO M, SUGENOYA A, NISHIHIRA T AND KUWANO M. (1993). Anti-angiogenic activity of arachidonic acid metabolism inhibitors in angiogenesis model systems involving human microvascular endothelial cells and neovascularization in mice. Int. J. Cancer, 55, 660-666.
    • (1993) Int. J. Cancer , vol.55 , pp. 660-666
    • Ito, K.1    Abe, T.2    Tomita, M.3    Morimoto, A.4    Kohno, K.5    Mori, T.6    Ono, M.7    Sugenoya, A.8    Nishihira, T.9    Kuwano, M.10
  • 11
    • 0028215674 scopus 로고
    • Biosynthesis of 12(S)-hydroxyeicosatetraenoic acid by B16 amelanotic melanoma cells is a determinant of their metastatic potential
    • LIU B, MARNETT LJ, CHAUDHARY A, JI C, BLAIR IA, JOHNSON CR, DIGLIO CA AND HONN KV. (1994). Biosynthesis of 12(S)-hydroxyeicosatetraenoic acid by B16 amelanotic melanoma cells is a determinant of their metastatic potential. Lab. Invest., 70, 314-323.
    • (1994) Lab. Invest. , vol.70 , pp. 314-323
    • Liu, B.1    Marnett, L.J.2    Chaudhary, A.3    Ji, C.4    Blair, I.A.5    Johnson, C.R.6    Diglio, C.A.7    Honn, K.V.8
  • 12
    • 0027971519 scopus 로고
    • 12(S)-Hydroxyeicosatetraenoic acid regulates DNA synthesis and protooncogene expression induced by epidermal growth factor and insulin in rat lens epithelium
    • LYSZ TW, ARORA JK, LIN C AND ZELENKA PS. (1994). 12(S)-Hydroxyeicosatetraenoic acid regulates DNA synthesis and protooncogene expression induced by epidermal growth factor and insulin in rat lens epithelium. Cell Growth Different., 5, 1069-1076.
    • (1994) Cell Growth Different. , vol.5 , pp. 1069-1076
    • Lysz, T.W.1    Arora, J.K.2    Lin, C.3    Zelenka, P.S.4
  • 14
    • 0024349903 scopus 로고
    • Decrease of polyunsaturated fatty acids and elevation of the oleic/stearic acid ratio in plasma and red blood cell lipids of malnourished cancer patients
    • MOSCONI C, AGRADI E, GAMBETTA A, BOZZETTI F AND GALLI C. (1989). Decrease of polyunsaturated fatty acids and elevation of the oleic/stearic acid ratio in plasma and red blood cell lipids of malnourished cancer patients. J. Parent. Ent. Nutr., 13, 501-504.
    • (1989) J. Parent. Ent. Nutr. , vol.13 , pp. 501-504
    • Mosconi, C.1    Agradi, E.2    Gambetta, A.3    Bozzetti, F.4    Galli, C.5
  • 15
    • 0026040838 scopus 로고
    • Molecular mechanisms of quinone cytotoxicity
    • O'BRIEN PJ. (1991). Molecular mechanisms of quinone cytotoxicity. Chem. Biol. Interactions, 80, 1-41.
    • (1991) Chem. Biol. Interactions , vol.80 , pp. 1-41
    • O'Brien, P.J.1
  • 16
    • 0026013272 scopus 로고
    • 2 synthase and 5-lipoxygenase with scavenging activity of active oxygen species. Synthesis of a novel series of (3-pyridylmethyl)benzoquinone derivatives
    • 2 synthase and 5-lipoxygenase with scavenging activity of active oxygen species. Synthesis of a novel series of (3-pyridylmethyl)benzoquinone derivatives. J. Med. Chem., 34, 267-276.
    • (1991) J. Med. Chem. , vol.34 , pp. 267-276
    • Ohkawa, S.1    Terao, S.2    Terashita, Z.3    Shibouta, Y.4    Nishikawa, K.5
  • 17
    • 0025905216 scopus 로고
    • Reduction of 2,3,5-Trimethyl-6-(3-pyridylmethyl)-1,4-benzoquinone by PB-3c cells and biological activity of its hydroquinone
    • OHKAWA S, TERAO T, MURAKAMI M, MATSUMOTO T AND GOTO G. (1991b). Reduction of 2,3,5-Trimethyl-6-(3-pyridylmethyl)-1,4-benzoquinone by PB-3c cells and biological activity of its hydroquinone. Chem. Pharm. Bull., 39, 917-921.
    • (1991) Chem. Pharm. Bull. , vol.39 , pp. 917-921
    • Ohkawa, S.1    Terao, T.2    Murakami, M.3    Matsumoto, T.4    Goto, G.5
  • 18
    • 0027931487 scopus 로고
    • Increased activity and expression of NAD(P)H: Quinone acceptor oxidoreductase in confluent cell cultures and within multicellular spheroids
    • PHILLIPS RM, DE LA CRUZ A, TRAVER RD AND GIBSON NW. (1994). Increased activity and expression of NAD(P)H: Quinone acceptor oxidoreductase in confluent cell cultures and within multicellular spheroids. Cancer Res., 54, 3766-3771.
    • (1994) Cancer Res. , vol.54 , pp. 3766-3771
    • Phillips, R.M.1    De La Cruz, A.2    Traver, R.D.3    Gibson, N.W.4
  • 19
    • 0028984873 scopus 로고
    • Over-expression of DT-diaphorase in transfected NIH 3T3 cells does not lead to increased anticancer quinone drug sensitivity: A questionable role for the enzyme as a target for bioreductively activated anticancer drugs
    • POWIS U, GASDASKA PY, GALLEGOS A, SHERRILL K AND GOODMAN D. (1995). Over-expression of DT-diaphorase in transfected NIH 3T3 cells does not lead to increased anticancer quinone drug sensitivity: A questionable role for the enzyme as a target for bioreductively activated anticancer drugs. Anticancer Res., 15, 1141-1146.
    • (1995) Anticancer Res. , vol.15 , pp. 1141-1146
    • Powis, U.1    Gasdaska, P.Y.2    Gallegos, A.3    Sherrill, K.4    Goodman, D.5
  • 20
    • 0025201334 scopus 로고
    • Effects of fatty acids and inhibitors of eicosanoid synthesis on the growth of a human breast cancer cell line in culture
    • ROSE DP AND CONNOLLY JM. (1990). Effects of fatty acids and inhibitors of eicosanoid synthesis on the growth of a human breast cancer cell line in culture. Cancer Res., 50, 7139-7144.
    • (1990) Cancer Res. , vol.50 , pp. 7139-7144
    • Rose, D.P.1    Connolly, J.M.2
  • 21
    • 0023612099 scopus 로고
    • The mitogenic effect of 15- and 12-hydroxyeicosatetraenoic acids on endothelial cells may be mediated via diacylglycerol kinase inhibition
    • SETTY BNY, GRAEBER JE AND STUART MJ. (1987). The mitogenic effect of 15- and 12-hydroxyeicosatetraenoic acids on endothelial cells may be mediated via diacylglycerol kinase inhibition. J. Biol. Chem., 262, 17613-17622.
    • (1987) J. Biol. Chem. , vol.262 , pp. 17613-17622
    • Setty, B.N.Y.1    Graeber, J.E.2    Stuart, M.J.3
  • 23
    • 0025688249 scopus 로고
    • Metabolism of mitomycin C by DT-diaphorase: Role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells
    • SIKGAL D, GIBSON NW, PREUSCH PC AND ROSS D. (1990). Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells. Cancer Res., 50, 7483-7489.
    • (1990) Cancer Res. , vol.50 , pp. 7483-7489
    • Sikgal, D.1    Gibson, N.W.2    Preusch, P.C.3    Ross, D.4
  • 24
    • 0023242184 scopus 로고
    • Enhancement of mammary tumorigenesis by dietary fat: Review of potential mechanisms
    • WELSCH CW. (1987). Enhancement of mammary tumorigenesis by dietary fat: review of potential mechanisms. Am. J. Clin. Nutr., 45, 192-202.
    • (1987) Am. J. Clin. Nutr. , vol.45 , pp. 192-202
    • Welsch, C.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.