Bronchial provocation tests: The rationale for using inhaled mannitol as a test for airway hyperresponsiveness

Swiss Medical Weekly

Volumn 132, Issue 13-14, 2002, Pages 151-158

  Leuppi, Jörg D ^a   Brannan, John D ^a   Anderson, Sandra D ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

Asthma; Bronchialprovocationtests; Exercise; Histamine; Mannitol; Methacholine; Osmoticaerosols

Indexed keywords

HISTAMINE; MANNITOL; METHACHOLINE; SODIUM CHLORIDE; STEROID;

ASTHMA; BRONCHUS HYPERREACTIVITY; DISEASE SEVERITY; EXERCISE; EXERCISE INDUCED ASTHMA; HUMAN; HYPERPNEA; POWDER; PROVOCATION TEST; RISK ASSESSMENT; SHORT SURVEY; TITRIMETRY;

EID: 0037029462     PISSN: 14247860     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (82)

1. Lung volumes and forced ventilatory flows
2. Airway responsiveness: Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults
3. The interrelationship among bronchial hyperresponsiveness, the diagnosis of asthma, and asthma symptoms
4. Relationships of bronchial responsiveness assessed by methacholine to serum IgE, lung function, symptoms, and diagnosis in 11 year old New Zealand children
5. The relationship of nonspecific bronchial responsiveness to respiratory symptoms in a random population sample
6. Prevalence of bronchial hyperresponsiveness and asthma in a rural adult population
7. Descriptive epidemiology, of bronchial reactivity in an adult population: Results from a community study
8. Factors influencing the occurrence of airway hyperreactivity in the general population: The importance of atopy and airway calibre
9. High prevalence of asthma in cross country skiers
10. High prevalence of bronchial hyperresponsiveness and asthma in ice hockey players
11. Lung function growth and its relation to airway hyperresponsiveness and recent wheeze. Results from a longitudinal population study
12. Exhaled nitric oxide levels in atopic children: Relation to specific allergic sensitisation, AHR and respiratory symptoms
13. Characteristics of bronchial hyperresponsiveness in "COPD" and "ASTHMA"
14. Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment
15. Airway responsiveness in asthma: Bronchial challenge with histamine and 4.5% sodium chloride before and after budesonide
16. Acute effect of sodium cromoglycate on airxvay narrowing induced by 4.5 percent saline aerosol. Outcome before and during treatment with aerosol corticosteroids in patients with asthma
17. Predictive markers of asthma exacerbations during stepwise dose-reduction of inhaled corticosteroids
18. The action of histamine on the respiratory tract in normal and asthmatic subjects
19. 20 determination in a random selection of young college students
20. Exercise but not methacholine differentiates asthma from chronic lung disease in children
21. Cold air inhalation and exercise-induced bronchoconstriction in relationship to methacholine bronchial responsiveness: Different patterns in asthmatic children and children with other chronic lung diseases
22. Changes in bronchial responsiveness to inhaled histamine over four years in middle aged male smokers and ex-smokers
23. Testing airway hyperresponsiveness using inhaled methacholine or histamine
24. Bronchial hyperresponsiveness in two populations of Australian schoolchildren. I. Relation to respiratory symptoms and diagnosed asthma
25. Human mast cells and airway smooth muscle cell interactions: Implications for asthma
26. Adenosine, methacholine, and exercise challenges in children with asthma or paediatric chronic obstructive pulmonary disease
27. Exercise, methacholine, and adenosine 5′-monophosphate callenges in children with asthma: Relation to severity of disease
28. Sensitivity and specificity of bronchial provocation testing. An evaluation of four techniques in exercise-induced bronchospasm
29. Asthma, asthmalike symptoms, chronic bronchitis, and the degree of bronchial hyperresponsiveness in epidemiologic surveys
30. Hypertonic saline challenge in an epidemiological survey of asthma in children
31. Hypertonic saline challenge in an adult epidemiological field survey
32. The effect of an inhaled corticosteroid (budesonide) on exercise-induced asthma in children
33. Place of physical exercise and bronchodilator drugs in the assessment of the asthmatic child
34. Standardization of exercise tests in asthmatic children
35. Exercise induced asthma. A Review
36. Time course of effect of disodium cromoglycate on exercise-induced asthma
37. Heat and water loss from the airways and exercise-induced asthma
38. Influence of heat and humidity on the airway obstruction induced by exercise in asthma
39. Role of respiratory heat exchange in production of exercise induced asthma
40. Sensitivity to heat and water loss at rest and during exercise in asthmatic patients
41. A reinterpretation of the effect of temperature and water content of the inspired air in exercise-induced asthma
42. Laboratory protocol for exercise asthma to evaluate salbutamol given by two devices
43. Hyperpnea: The common stimulus for bronchospasm in asthma during exercise and voluntary isocapnic hyperventilation
44. Eucapnic voluntary hyperventilation of compressed gas mixture. A simple system for bronchial challenge by respiratory heat loss
45. Eucapnic voluntary hyperventilation as a bronchoprovocation technique. Development of a standardized dosing schedule in asthmatics
46. Provocation by eucapnic voluntary hyperpnoea to identify exercise-induced bronchoconstriction
47. Bronchial hyperreactivity in response to inhalation of ultrasonically nebulised solutions of distilled water and saline
48. Hyperosmolar triggering of histamine release from human basophils
49. Evaluation of ultrasonically nebulised solutions as a provocation in patients with asthma
50. Inhalation provocation tests using non-isotonic aerosols
51. Inhalational challenge using hypertonic saline in asthmatic subjects: A comparison with responses to hyperpnoea, methacholine, and water
52. Hyperosmolarity as the stimulus to asthma induced by hyperventilation?
53. A comparison between the airway response to isocapnic hyperventilation and hypertonic saline in subjects with asthma
54. Inhaled steroids modify bronchial responses to hyperosmolar saline
55. Nedocromil sodium inhibits the airway response to hyperosmolar challenge in patients with asthma
56. The hyperosmolar release of histamine from bronchoalveolar mast cells and its inhibition by sodium cromoglycate
57. Histamine release from mast cells and basophils
58. The protective effect of nedocromil sodium and other drugs on airway narrowing provoked by hyperosmolar stimuli: A role for the airway epithelium
59. Asthma prophylaxis agents alter the function of an airway epithelial chloride channel
60. Prevalence of bronchial hyperresponsiveness to 4.5% saline and its relation to asthma and allergy symptoms in Austrian children
61. Lung function and bronchial provocation tests for intending divers with a history of asthma
62. Epidemiological association of airway inflammation with asthma symptoms and airway hyperresponsiveness in childhood
63. Airway mast cells and eosinophils correlate with clinical severity and airway hyperresponsiveness in corticosteroid-treated asthma
64. A new method for bronchial provocation testing in asthmatic subjects using a dry powder of mannitol
65. Inhaled mannitol identifies responsiveness to eucapnic hyperventilation
66. Inhaled mannitol identifies methacholine-responsive children with active asthma
67. Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol
68. Repeatability of bronchial responsiveness to mannitol dry powder in children with asthma
69. Inhaled mannitol does not cause bronchoconstriction in non-asthmatic healthy persons
70. Nedocromil sodium inhibits responsiveness to inhaled mannitol in asthmatic subjects
71. Inhalation of mannitol, used as a model for exercise-induced bronchoconstriction (EIB), causes release of leukotrienes and a mast cell marker in asthmatic subjects
72. Inhalation of dry powder mannitol increases mucociliary clearance
73. The effect of inhaled mannitol on bronchial mucus clearance in cystic fibrosis patients: A pilot study
74. Inhalation of dry powder mannitol improves clearance of mucus in patients with bronchiectasis
75. Responsiveness to mannitol in asthmatic subjects with exercise and hyperventilation-induced asthma
76. Budesonide reduces sensitivity and reactivity to inhaled mannitol in asthmatic subjects
77. Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma
78. Nasal hyperosmolar challenge with a dry powder of mannitol in patients with allergic rhinitis. Evidence for epithelial cell involvement
79. 20 of methacholine
80. PC(20) adenosine 5′monophosphate is more closely associated with airway inflammation in asthma than PC(20) methacholine
81. Markers of airway inflammation and airway hyperresponsiveness in patients with well-controlled asthma