The catalytic role of the copper ligand H172 of peptidylglycine α-hydroxylating monooxygenase (PHM): A spectroscopic study of the H172A mutant

Biochemistry

Volumn 41, Issue 44, 2002, Pages 13274-13282

  Jaron, Shulamit ^a   Mains, Richard E ^b   Eipper, Betty A ^b   Blackburn, Ninian J ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLUE SHIFT;

CARBON MONOXIDE; COPPER; ENZYMES; SUBSTRATES;

BIOCHEMISTRY;

ALPHA AMIDATING ENZYME; COPPER; LIGAND; MUTANT PROTEIN;

ABSORPTION SPECTROSCOPY; ANIMAL CELL; ARTICLE; BINDING SITE; CATALYSIS; CHO CELL; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME SUBSTRATE; FOURIER TRANSFORMATION; GENE MUTATION; INFRARED SPECTROSCOPY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; STOICHIOMETRY;

ALANINE; ANIMALS; BINDING SITES; CARBON MONOXIDE; CATALYSIS; CHO CELLS; COPPER; CRICETINAE; ENZYME ACTIVATION; HISTIDINE; IMIDAZOLES; LIGANDS; MIXED FUNCTION OXYGENASES; MULTIENZYME COMPLEXES; OLIGOPEPTIDES; OXIDATION-REDUCTION; RECOMBINANT PROTEINS; SPECTROMETRY, X-RAY EMISSION; SPECTROPHOTOMETRY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SPECTRUM ANALYSIS; SUBSTRATE SPECIFICITY; X-RAYS;

ANIMALIA;

EID: 0037027322     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi020404z     Document Type: Article

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