A route to 5-substituted dibenzofurans by anionic cycloaromatization of 2-(6-substituted 3-hexen-1,5-diynyl)phenyl tert-butyldimethyl ethers and related molecules

Angewandte Chemie - International Edition

Volumn 41, Issue 21, 2002, Pages 4077-4079

  Wu, Ming Jung ^a   Lee, Chia Ying ^a   Lin, Chi Fong ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cyclization; Enediyne; Fused ring systems; Heterocycles

Indexed keywords

ETHERS; SODIUM COMPOUNDS; SYNTHESIS (CHEMICAL);

CYCLOAROMATIZATION REACTION;

AROMATIC COMPOUNDS;

DIBENZOFURAN DERIVATIVE; DIMETHYL ETHER; SILANE DERIVATIVE; TERT BUTYLDIMETHYLSILYL ETHER DERIVATIVE; UNCLASSIFIED DRUG;

AROMATIZATION; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE;

EID: 0037021087     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3773(20021104)41:21<4077::AID-ANIE4077>3.0.CO;2-Z     Document Type: Article

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25. abstract
26. 4) gave 2-iodo-4-tert-butylphenol in 31% yield. Compound 12k was treated with tert-butyldimethylsilyl chloride using imidazole as a base to give 13k in 91% yield. Finally, compound 13k was coupled with 7a using palladium as a catalyts to give 11k (TBS= tert-butyldimethylsilyl in 38% yield.