Dicationic dibenzofuran derivatives as anti-Pneumocystis carinii pneumonia agents: Synthesis, DNA binding affinity, and anti-P. carinii activity in an immunosuppressed rat model

European Journal of Medicinal Chemistry

Volumn 34, Issue 3, 1999, Pages 215-224

  Wang, Sihe ^a   Hall, James Edwin ^b,c   Tanious, Farial A ^d   Wilson, W David ^d   Patrick, Donald A ^b   McCurdy, Donald R ^b   Bender, Brenden C ^b   Tidwell, Richard R ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c IL   (United States)

^d GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Amidines; Amidoximes; Dibenzofurans; DNA; Pneumocystis carinii pneumonia

Indexed keywords

2,8 DIAMIDINODIBENZOFURAN; 3,7 DI(2 IMIDAZOLINYL)DIBENZOFURAN; ANTIPROTOZOAL AGENT; PENTAMIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROTOZOAL ACTIVITY; ARTICLE; BINDING AFFINITY; DRUG DNA BINDING; DRUG POTENCY; IMMUNE DEFICIENCY; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PNEUMOCYSTIS CARINII; PNEUMOCYSTIS PNEUMONIA; RAT;

EID: 0032728386     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(99)80054-3     Document Type: Article

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