A modular, general and enantiospecific strategy for the synthesis of CVS 1778 analogs: Inhibitors of factor Xa

Tetrahedron Letters

Volumn 43, Issue 45, 2002, Pages 8177-8180

  Organ, Michael G ^a   Xu, Juan ^a   N’Zemba, Blaise ^a  

^a YORK UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10A INHIBITOR; CVS 1778; LACTAM DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG SYNTHESIS; ENANTIOMER; MOLECULAR SIZE; REACTION ANALYSIS;

EID: 0037020578     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)01924-X     Document Type: Article

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19. Other sulfonamides prepared include ethyl, tosyl and camphorsulfonyl, all of which coupled in excess of 70% yield.
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