Incision of a 1,3-intrastrand d(GpTpG)-cisplatin adduct by nucleotide excision repair proteins from yeast

DNA Repair

Volumn 1, Issue 9, 2002, Pages 731-741

  Kong, Stephanie E ^a   Svejstrup, Jesper Q ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

DNA lesions; Nucleotide excision repair; Repairosome; Saccharomyces cerevisiae

Indexed keywords

CISPLATIN; DEOXYRIBONUCLEOPROTEIN; FUNGAL PROTEIN; NUCLEOTIDE; OLIGONUCLEOTIDE; CELL EXTRACT; CIRCULAR DNA; CISPLATIN DNA ADDUCT; CISPLATIN-DNA ADDUCT; DEOXYRIBONUCLEASE; DNA BINDING PROTEIN; ENDONUCLEASE; RAD1 PROTEIN, S CEREVISIAE; RAD10 PROTEIN, S CEREVISIAE; RAD2 PROTEIN, S CEREVISIAE; RNA POLYMERASE II; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; EXCISION REPAIR; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN MODIFICATION; PROTEIN PURIFICATION; YEAST; DNA REPAIR; DRUG EFFECT; ENZYMOLOGY; ESCHERICHIA COLI; HELA CELL; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE;

MAMMALIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

CELL EXTRACTS; CISPLATIN; DNA ADDUCTS; DNA REPAIR; DNA, CIRCULAR; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; ENDONUCLEASES; ESCHERICHIA COLI; FUNGAL PROTEINS; HELA CELLS; HUMANS; RNA POLYMERASE II; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0037019599     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1568-7864(02)00080-0     Document Type: Article

References (33)

1. Nucleotide excision repair in mammalian cells
2. Stable binding of human XPC complex to irradiated DNA confers strong discrimination for damaged sites
3. Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair
4. Sequential assembly of the nucleotide excision repair factors in vivo
5. Reconstitution of TFIIH and requirement of its DNA helicase subunits, Rad3 and Rad25, in the incision step of nucleotide excision repair
6. Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein
7. Mechanism of open complex and dual incision formation by human nucleotide excision repair factors
8. TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair
9. Yeast DNA-repair gene RAD14 encodes a zinc metalloprotein with affinity for ultraviolet-damaged DNA
10. An affinity of human replication protein A for ultraviolet-damaged DNA: Implications for damage recognition in nucleotide excision repair
11. Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA
12. Enhancement of damage-specific DNA binding of XPA by interaction with the ERCC1 DNA repair protein
13. Isolation of human complexes proficient in nucleotide excision repair
14. Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease
15. XPG endonuclease makes the 3′ incision in human DNA nucleotide excision repair
16. A conserved 5′ to 3′ exonuclease activity in the yeast and human nucleotide excision repair proteins RAD2 and XPG
17. Analysis of incision sites produced by human cell extracts and purified proteins during nucleotide excision repair of a 1,3-intrastrand d(GpTpG)-cisplatin adduct
18. Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5′ and the 6th phosphodiester bond 3′ to the photodimer
19. DNA repair by eukaryotic nucleotide excision nuclease: Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevis oocytes
20. Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome
21. Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a pre-assembled repairosome
22. DNA repair and transcription
23. The multiple roles of transcription/repair factor TFIIH
24. Affinity purification and partial characterization of a yeast multiprotein complex for nucleotide excision repair using histidine-tagged Rad14 protein
25. Nucleotide excision repair in yeast is mediated by sequential assembly of repair factors and not by a pre-assembled repairosome
26. Specific initiation by RNA polymerase I in a whole cell extract from yeast
27. In vitro transcription: Whole cell extract
28. Assay for nucleotide excision repair protein activity using fractionated cell extracts and UV-damaged plasmid DNA
29. Purification and properties of Saccharomyces cerevisiae RNA polymerase II general initiation factor α
30. Assessing the requirements for nucleotide excision repair proteins of Saccharomyces cerevisiae in an in vitro system
31. Nucleotide excision repair of DNA in cell-free extracts of the yeast Saccharomyces cerevisiae
32. The RAD7, RAD16, and RAD23 genes of Saccharomyces cerevisiae: Requirement for transcription-independent nucleotide excision repair in vitro and interactions between the gene products