The TBP-inhibitory domain of taf145 limits the effects of nonclassical transcriptional activators

Current Biology

Volumn 12, Issue 11, 2002, Pages 934-937

  Cheng, Jason X ^a   Nevado, Julian ^b   Lu, Zhen ^a   Ptashne, Mark ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b HOSPITAL UNIVERSITARIO DE GETAFE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; OLIGONUCLEOTIDE; TATA BINDING PROTEIN; TRANSACTIVATOR PROTEIN;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

BASE SEQUENCE; FUNGAL PROTEINS; OLIGONUCLEOTIDES; TATA-BOX BINDING PROTEIN; TRANS-ACTIVATORS; SUPPORT, U.S. GOV'T, P.H.S.;

BACTERIA (MICROORGANISMS); EUKARYOTA; MYXOGASTRIA;

EID: 0037018851     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00866-7     Document Type: Article

References (22)

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4. Activation of transcription in vitro by recruitment of the yeast RNA polymerase II holoenzyme
5. Stimulation of RNA polymerase II transcription initiation by recruitment of TBP in vivo
6. Activator-mediated recruitment of the RNA polymerase II machinery is the predominant mechanism for transcriptional activation in yeast
7. Transcriptional activation by artificial recruitment in yeast is influenced by promoter architecture and downstream sequences
8. Active site-directed protein regulation
9. Signaling through scaffold, anchoring, and adaptor proteins
10. SH3 domains: Complexity in moderation
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12. The yeast TAF145 inhibitory domain and TFIIA competitively bind to TATA-binding protein
13. Solution structure of a TBP-TAF(II)230 complex: Protein mimicry of the minor groove surface of the TATA box unwound by TBP
14. TBP-associated factors are not generally required for transcriptional activation in yeast
15. Yeast TAF(II)145 functions as a core promoter selectivity factor, not a general coactivator
16. Distinct classes of yeast promoters revealed by differential TAF recruitment
17. Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock
18. c-Jun binds the N terminus of human TAF(II)250 to derepress RNA polymerase II transcription in vitro
19. Acetyl coenzyme A stimulates RNA polymerase II transcription and promoter binding by transcription factor IID in the absence of histones
20. II145 that are functionally interchangeable for inhibiting TBP-DNA interactions in vitro and in promoting yeast cell growth in vivo
21. Selection of peptides that functionally replace a zinc finger in the Sp1 transcription factor by using a yeast combinatorial library