Total Syntheses of (-)-Fumiquinazolines C, E, and H

Organic Letters

Volumn 4, Issue 7, 2002, Pages 1087-1090

  Snider, Barry B ^a   Zeng, Hongbo ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; FUMIQUINAZOLINE C; FUMIQUINAZOLINE E; FUMIQUINAZOLINE H; QUINAZOLINE DERIVATIVE;

ARTICLE; ASPERGILLUS FUMIGATUS; CHEMISTRY; CYCLIZATION; STEREOISOMERISM; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ANTIBIOTICS, ANTINEOPLASTIC; ASPERGILLUS FUMIGATUS; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; INDICATORS AND REAGENTS; QUINAZOLINES; STEREOISOMERISM;

EID: 0037018453     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol017215d     Document Type: Article

References (24)

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19. 1
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21. In fumiquinazoline C (5), 14, 22, and 23 there is an NOE between H-2 and H-27. In fumiquinazoline H (6) there is an NOE between H-2 and H-18. In Cbz-fumiquinazoline C (14) and 22, the Cbz benzyl protons are shifted upfield to δ 4.40-4.25 as a result of shielding by the quinazolinone ring.
22. 3CN without HOAc.
23. 16
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