CDK phosphorylation of Drc1 regulates DNA replication in fission yeast

Current Biology

Volumn 12, Issue 7, 2002, Pages 599-605

  Noguchi, Eishi ^a   Shanahan, Paul ^a   Noguchi, Chiaki ^a   Russell, Paul ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTA; MYXOGASTRIA; SCHIZOSACCHAROMYCES POMBE;

CDC18 PROTEIN, S POMBE; CELL CYCLE PROTEIN; CIG2 PROTEIN, S POMBE; CYCLIN B; CYCLIN DEPENDENT KINASE 1; CYCLINE; FUNGAL DNA; FUNGAL PROTEIN; HYBRID PROTEIN; RUM1 PROTEIN, S POMBE; SACCHAROMYCES CEREVISIAE PROTEIN; SCHIZOSACCHAROMYCES POMBE PROTEIN; SLD2 PROTEIN, S CEREVISIAE;

ARTICLE; BIOSYNTHESIS; DNA REPLICATION; GENETICS; METABOLISM; PHOSPHORYLATION; SCHIZOSACCHAROMYCES;

CDC2 PROTEIN KINASE; CELL CYCLE PROTEINS; CYCLIN B; CYCLINS; DNA REPLICATION; DNA, FUNGAL; FUNGAL PROTEINS; PHOSPHORYLATION; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS;

EID: 0037006806     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00739-X     Document Type: Article

References (27)

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2. Regulation of chromosome replication
3. Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms
4. cdk2
5. SId2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication
6. DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae
7. Dpb11, which interacts with DNA polymerase II(ε) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint
8. Dpb11 controls the association between DNA polymerases alpha and ε and the autonomously replicating sequence region of budding yeast
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10. Negative regulation of Cdc18 DNA replication protein by Cdc2
11. Phosphorylation controls timing of Cdc6p destruction: A biochemical analysis
12. The stability of the Cdc6 protein is regulated by cyclin-dependent kinase/cyclin B complexes in Saccharomyces cerevisiae
13. The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle
14. Functions of fission yeast orp2 in DNA replication and checkpoint control
15. + gene product couples S phase to START and mitosis
16. Mitotic DNA damage and replication checkpoints in yeast
17. Cdc18p can block mitosis by two independent mechanisms
18. Chk1 and Cds1: Linchpins of the DNA damage and replication checkpoint pathways
19. Rum1 and Cdc18 link inhibition of cyclin-dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe
20. + gene
21. Regulation of the G1 phase of the cell cycle by periodic stabilization and degradation of th p25rum1 CDK inhibitor
22. cdc2 promotes both S-phase and mitosis in the absence of G1-cyclins
23. Cig2, a B-type cyclin, promotes the onset of S in Schizosaccharomyces pombe
24. cdc10 function
25. +
26. Damage and replication checkpoint control in fission yeast is ensured by interactions of crb2, a protein with BRCT motif, with cut5 and chk1
27. S-Cdk-dependent phosphorylation of SId2 essential for chromosomal DNA replication in budding yeast